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What happens when businesses start treating people like resources instead of human beings? In this episode of Unstoppable Brain, Dr. Kyra Bobinet sits down with bestselling author and performance researcher Marcus Buckingham to explore the business case for love.
Drawing from his new book, Design Love In, Marcus explains why love is far more than a soft idea. It is a measurable force that shapes employee engagement, customer loyalty, resilience, productivity, and long-term business value.
Marcus shares why people need “red threads” in their workday, how leaders can create stronger connections with remote teams, and why weekly check-ins can have a major impact on performance. He also examines the growing role of artificial intelligence in the workplace and asks a crucial question: Can AI help humans flourish, or are companies using it in ways that damage the customer experience?
You’ll learn:
• Why love is a serious business metric
• How to identify the work that gives you energy
• Why employees need at least 20% “red threads” in their day
• How leaders can build connection across remote teams
• The five feelings that create loving experiences
• Why AI struggles to replace genuine human care
• How to handle difficult leadership decisions with compassion
Marcus Buckingham is a leading authority on human strengths and performance. He is the bestselling author of First, Break All the Rules, Love + Work, and Design Love In.
Subscribe to Unstoppable Brain for more conversations that turn neuroscience into practical strategies for behavior change and a better life.
00:00 Cold Open
00:45 Introducing Marcus Buckingham
02:07 Why Love Is the Most Powerful Force in Business
05:31 Why Business Leaders Avoid the Word “Love”
06:40 What Marcus Learned After Selling His Company
09:40 Love Is Oxygen
10:14 Finding Your Red Threads at Work
12:39 How Love Changes Your Brain
13:34 Why You Need 20% Red Threads in Your Day
17:10 You Can’t Love What You Can’t See
18:15 The Weekly Check-In Every Manager Should Use
20:45 How Remote Teams Build Real Connection
23:20 The Five Feelings That Create Love
25:03 Control, Harmony, and Significance
28:07 Why People Need the Warmth of Others
29:44 Growth, Learning, and Loyalty
34:49 What Love Really Means
36:44 When Firing Someone Can Be an Act of Love
39:31 Can Humans Love AI?
42:03 Can AI Love Humans?
43:25 Is AI Damaging the Customer Experience?
48:27 Will AI Crush Human Connection?
52:08 The Data Behind the Business Case for Love
57:00 Why Business Schools Overlook Love
58:00 Love, Motivation, and the Habenula
01:07:00 How to Fire Someone Lovingly
01:11:50 Final Takeaways -
Traditional healthcare is struggling to keep up with the needs of patients.
Telemedicine, wearable devices, AI, and digital health tools have created new ways to monitor our health and access care. Yet many patients still face long wait times, confusing systems, and limited access when they need an in-person appointment.
In this episode of Unstoppable Brain, Dr. Kyra Bobinet speaks with Dr. Joseph Kvedar, a professor of dermatology at Harvard Medical School, president of the American Telemedicine Association, and author of The Internet of Healthy Things and The New Mobile Age.
Dr. Kvedar has spent decades studying the future of healthcare. He saw the rise of telemedicine and wearable technology long before either became mainstream. In this conversation, he explains where digital health has delivered on its promise, where the healthcare system has fallen short, and why some problems still require a human doctor in the room.
The discussion covers the limits of AI in healthcare, the growth of telemedicine, the role of wearable devices such as Apple Watch and Oura Ring, the risks of private equity in medicine, and the growing complexity patients face when trying to get care.
Dr. Kvedar also shares his prediction for the next major shift in healthcare: digital twins. A digital version of your body could one day help doctors test treatments, predict your response to medications, and create more personalized care.
In this episode, you’ll learn:
Why traditional healthcare still feels broken
Where telemedicine improves the patient experience
Why AI still has major limits in medicine
How wearable technology gives doctors a fuller picture of your health
Why motivation matters more than tracking alone
How private equity can change the patient experience
Why digital twins could shape the future of personalized medicine
How innovators stay committed when their ideas are years ahead of the market
Subscribe to Unstoppable Brain for practical conversations about neuroscience, behavior change, personal growth, and the tools that can help you build the life you want.
Chapters
00:00 Why traditional healthcare still feels broken
00:15 Welcome to Unstoppable Brain
01:23 Predicting the rise of digital health
03:51 The early vision for a digital health assistant
05:00 The rise of wearables and the Oura Ring
05:40 Why healthcare can’t “move fast and break things”
08:17 The risks of AI tools without clinical research
10:50 Where AI performs well, and where it fails
13:37 Why digital health is having a major moment
14:33 Wearables give a continuous picture of your health
16:23 Has personalized medicine gone too far?
18:03 Longevity trends, hype, and scientific evidence
21:25 Why telemedicine pioneers felt like outsiders
23:02 Has digital health made care harder to navigate?
24:31 How patient portals improve access
26:28 The biggest failure of digital healthcare
30:17 Retail healthcare, Amazon, Ro, Hims, and Hers
32:16 Why patients choose telemedicine
34:15 The risks of private equity in healthcare
38:23 Why patients feel powerless inside the system
41:48 Why in-person healthcare still struggles
44:48 The digital side of healthcare is working
45:42 Why AI still can’t replace a physical exam
48:03 Wearables, motivation, and lasting behavior change
52:00 Advice for people challenging conventional thinking
55:35 The future of digital health
56:11 How digital twins could transform medicine -
Saknas det avsnitt?
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What helps people thrive when everything keeps changing?
In this episode of Unstoppable Brain, Liz Tran joins Dr. Kyra Bobinet for a deep conversation about adaptability, behavior change, and the skill set people need to survive in an unpredictable world.
Liz explains why IQ and EQ no longer tell the full story, and why “AQ” or Agility Quotient may be the defining trait of modern leadership. Drawing from years coaching fast-growing tech CEOs, she breaks down the habits, mindsets, and emotional skills that help people navigate uncertainty without losing themselves.
They discuss the neuroscience behind resistance to change, the importance of anchors and routines, how to recover faster after setbacks, and why discomfort is often the clearest sign of growth.
The conversation also explores how personality shapes adaptability, the danger of perfectionism, why human connection matters more in an AI-driven world, and how learning to operate in uncertainty can transform your work, relationships, and identity.If you’ve felt overwhelmed by constant change, this episode offers a practical framework for staying grounded while continuing to grow.
Topics Covered:What “AQ” means and why it mattersWhy successful founders constantly reinvent themselvesThe difference between IQ, EQ, and AQHow adaptability impacts leadership and performanceThe neuroscience of fear, failure, and resistance to changeThe four pillars of agility: Anchors, Bets, Classroom, and DiscomfortWhy routines and grounding habits matterHow to recover faster after setbacksThe danger of perfectionism and overplanningHuman connection in an AI-driven worldThe four AQ archetypes and how they operateWhy discomfort is a signal of growthHow to build resilience during uncertaintyChapter Timestamps
00:00 Why adaptability matters more than ever
00:45 The founders who kept reinventing themselves
03:00 Why agility became the defining trait of success
05:00 The problem with fixed identities
08:00 Childhood pain, ambition, and achievement
12:00 Beginner’s mind and unlearning old patterns
14:40 Why AQ can grow over time
15:00 The neuroscience of resistance to change
18:00 Why people repeat the same mistakes
19:00 The importance of anchors and stability
21:00 Meditation, routines, and emotional grounding
24:00 Energy audits and managing depletion
29:00 The three types of anchors
31:30 Bets and learning to operate in uncertainty
35:00 Recovery rate vs. success rate
37:00 Why human connection matters more than ever
41:00 The AQ archetypes explained
44:00 The Astronaut vs. the Neurosurgeon
47:00 The Novelist vs. the Firefighter
51:00 Why life should feel like a classroom
55:00 Discomfort as a signal of growth
57:00 Fear, neuroscience, and adaptability -
What if stress isn’t the problem, but how your brain responds to it is?
In this episode of Unstoppable Brain, Dr. Kyra Bobinet sits down with physician and resilience expert Eva Selhub to break down what’s actually happening in your brain when you feel overwhelmed, burned out, or stuck in unhealthy patterns.
Dr. Selhub shares how stress rewires your brain, why resilience is often misunderstood, and how small daily shifts can help you regain control.
You’ll learn:
Why resilience is not about pushing harderHow stress creates addictive behavior loopsWhat your brain is doing when you feel overwhelmedWhy modern life is keeping you stuck in survival modeHow nature, connection, and awareness reset your systemSimple practices to reduce stress and restore balance
This conversation blends neuroscience, behavior change, and real-world experience to give you a clear path forward.
⏱️ Timestamps
00:00 – Why Dr. Eva Selhub almost left medicine
00:18 – Burnout, dopamine, and modern stress
01:33 – Building a career around “non-traditional” medicine
03:00 – The moment that changed everything
05:34 – Save lives vs help people live
06:21 – Compounding trauma and burnout
07:56 – What resilience actually means
11:13 – Why resilience is misunderstood
13:33 – The real definition of resilience
17:27 – Thriving vs surviving
18:25 – Hormesis and stress adaptation
20:13 – Neuroplasticity, good vs bad habits
22:55 – How your brain creates coping behaviors
26:46 – The hidden cost of stress loops
29:04 – Why modern life keeps you overwhelmed
31:11 – Phone addiction and dopamine cycles
35:01 – The missing piece: connection and love
37:54 – Why mindset matters more than biology alone
40:16 – Finding self-love through nature
43:30 – Why modern identity increases stress
46:18 – High achievers and burnout
47:51 – The “love response” explained
52:31 – Nature, healing, and connection
57:37 – Daily habits to build resilience
01:00:08 – Final thoughts and where to find Dr. Selhub -
What if the problem isn’t your discipline… but your approach?
In this episode of Unstoppable Brain, Dr. Kyra Bobinet sits down with neuroscientist and author Anne-Laure Le Cunff to break down a smarter way to change your life.
After a health scare forced her to rethink everything, Anne-Laure walked away from a successful career at Google and rebuilt her life using what she calls the “experimental mindset.”
Instead of chasing big goals, she focuses on small, repeatable experiments that help you learn what actually works for you.
This conversation covers:
Why announcing goals can make you less likely to succeedHow to use “tiny experiments” to create real changeThe danger of tying your self-worth to productivityHow to handle criticism and build resilienceWhy imperfection and learning in public accelerate growthThe difference between legacy and generativity
If you’ve ever felt stuck, overwhelmed, or unsure of your next move, this episode gives you a practical framework to move forward.
⏱️ TIMESTAMPS00:00 – The health scare that changed everything
01:45 – From Google to neuroscience: a non-linear path
03:10 – The “life quake” moment
06:00 – Fear, family, and leaving a stable career
09:30 – Finding community during uncertainty
12:00 – Learning in public and facing criticism
16:30 – Dealing with negative feedback and self-doubt
19:00 – Journaling, relationships, and emotional resilience
23:30 – Why perfection is the wrong goal
27:00 – Separating self-worth from productivity
30:30 – The experimental mindset explained
33:40 – Why goals fail (and what works instead)
36:00 – Tiny experiments vs big goals
40:00 – How to track progress without self-judgment
44:00 – Confidence, language, and reframing failure
49:00 – Legacy vs generativity
52:30 – How to make an impact right now
54:30 – Apprentice → Artisan → Architect framework
58:30 – Scaling your work without burning out
1:02:00 – Letting go of control and trusting your team
1:05:00 – How to improve as a creator (powerful closing insight) -
Why do you keep quitting on your goals, even when you know exactly what to do?
In the first episode of Unstoppable Brain, Dr. Kyra Bobinet sits down with behavioral expert and bestselling author Nir Eyal to break down the real reason people fail, and it has nothing to do with discipline, talent, or outside circumstances.
The problem is belief.
Nir explains why most people never follow through, even after reading the right books, hiring coaches, or learning proven systems. He introduces the Motivation Triangle, a framework that reveals the missing piece behind behavior change, and shows how limiting beliefs quietly sabotage your progress.
You’ll also hear:
Why quitting, not failure, is the real problemHow belief drives consistency more than willpowerThe hidden mental patterns behind weight loss, habits, and performanceWhy pain, discomfort, and resistance don’t mean stopHow to rewire limiting beliefs into ones that drive actionThe science behind attention, motivation, and persistenceThis conversation blends neuroscience, psychology, and real-life experience into a clear system you can apply immediately.
If you’ve ever said: “I know what to do, I just don’t do it”
This episode explains why.
Connect with Nir: https://www.nirandfar.com/
Order Beyond Belief: https://www.amazon.com/Beyond-Belief-Science-Backed-Limiting-Breakthrough/dp/0593852036
⏱️ TIMESTAMPS
00:00 Why people fail their goals
00:24 Meet Nir Eyal
01:30 Why this book matters more than his others
03:30 The real problem with behavior change
06:00 The Motivation Triangle explained
07:00 Why belief is the missing piece
09:00 Emotional eating and behavior patterns
11:00 Why consistency beats the “perfect plan”
13:00 The real reason people quit
14:30 Breaking limiting beliefs
16:00 Pain, avoidance, and behavior loops
18:00 The power of attention and the brain
22:00 Chronic pain and belief systems
26:00 Why suffering is optional
31:00 The rat experiment that changes everything
34:00 How belief drives endurance
37:00 Controlling attention like a superpower
41:00 Reframing relationships and perception
46:00 The Byron Katie method explained
52:00 Labels, identity, and self-limiting beliefs
