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  • Vincent travels to the University of Heidelberg to speak with Volker Lohmann about his career and the research of his laboratory on hepatitis C virus, hepatitis A virus, and norovirus.

    Host: Vincent Racaniello

    Guests: Volker Lohmann

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier HCV human challenge studies (Lancet Gastro Hepatol) Comparison of HCV and HAV infections (J Hepatol) HCV cell culture systems (J Med Chem)

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin deep dives into recent domestic and global measles and mpox outbreaks, before reviewing recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2, discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how much oxygen is necessary for effective treatment of severe disease, how COVID-19 effects the cardiovascular system of children and adolescents with long COVID and how iron metabolism may be altered during long COVID.

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    Links for this episode Measles tracking (CDC) Measles in Cook County (MMWR) Gaps in measles vaccination drives viral surges (Infectious Disease Advisor) Misinformation impacts public health? Seriously? (ID Society) CDC alert for global and domestic measles cases and outbreaks (CDC) Mpox in Kamituga associated with outbreak in DRB (Eurosurviellance) Mpox in US, 2023 (MMWR) Mpox in DRC, 2024 (reliefweb) CDC guidance for respiratory diseases, COVID antiviral & emergence of clade I mpox (ID Society) ~5% of infected dead from mpox (CIDRAP) First cases of mpox in Republic of Congo (AP News) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Multisystem inflammatory syndrome in children 2023 (MMWR) Guidance for COVID-19 in children and adolescents (JPIDS) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) High/low oxygenation target (JAMA) How much oxygen is needed (JAMA) Orthostatic intolerance in long COVID and healthy volunteers (JMV) Autonomic cardiac function in children and adolescents with long COVID (European Journal of Pediatrics) Long COVID iron dysregulation and inflammatory stress erythropoiesis (Nat Imm) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1098 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

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  • Vincent travels to the fifth Giant Virus Meeting in Tegernsee, Germany and speaks with Sheree Yau and Victoria Queiroz about their research on picoeukaryotes (tiny algal cells) and their viruses, pithoviruses, and an educational kit for virology classes.

    Host: Vincent Racaniello

    Guests: Sheree Yau and Victoria Queiroz

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier 8:16 Virophage control of antarctic algal host-virus dynamics (PNAS) Timestamps by Jolene. Thanks! Virus-host coexistence in phytoplankton through the genomic lens (Sci Adv) Two groups of pithoviruses (J Virol) Educational toolkit for virology classes (J Virol)

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin highlights measles outbreaks throughout the continental US, reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing if vaccination protected children from the development of long COVID or cardiovascular diseases associated with virus infection, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, how COVID-19 effects the autonomic nervous system, and if nirmatrelvir-ritonavir protects against adverse cardiovascular effects following SARS-CoV-2 infection.

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    Links for this episode Measles everywhere (CDC) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Estimating niresevimab effectiveness for infants (MMWR) More than 100 children died of influenza (NBS News) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Did the vaccine protect children against Long COVID (Pediatrics) Did COVID-19 vaccination impact cardiovascular diseases? (Nat Comm) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Updated respiratory infection guidelines (CDC) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID trial for autonomic nervous system dysfunction (NIH) Nirmatrelvir-ritonavir impact on myocardial injury and long-term cardiovascular outcomes in COVID-19 hospitalized patients (Cardiovascular Drugs and Therapy) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1096 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews heterosexual transmission of clade I Mpox virus, continued circulation of oropouche virus in South America, herpesviruses in South American fur seals and sea lions, sex-specific differences in physiological responses to SARS-CoV-2 infection, underdetected dispersal and extensive local transmission drove the 2022 mpox epidemic, and a humanized mouse model for adenovirus-associated virus gene therapy.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Angela Mingarelli

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Heterosexual transmission of clade I Mpox virus (Emerg Inf Dis) Continued circulation of oropouche virus (PAHO and WHO) Herpesviruses in fur seals and sea lions (PLoS One) Sex-specific effects of SARS-CoV-2 infection (PLoS One) Drivers of 2022 Mpox virus epidemic (Cell) How AAV gene transfer works (YouTube) Humanized mouse model for AAV gene therapy (Nat Comm) Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – Baden Powell – Manha de Carneval
    Angela – Upcoming Health & Fitness podcast from MicrobeTV
    Rich – Mark Smith Photography
    Alan – OpenVertebrate (and Science article on it)
    Vincent – Veterinary apparel for the veterinary nerd

    Listener Pick

    Anne – Why Reed Jobs is betting on cancer innovations

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, effectiveness of the new SARS-CoV-2 vaccines and the combination of vaccination and antiviral therapy against the development of disease, continues to dispel the myth of viral rebound, how to pay for paxlovid, the lack of evidence supporting ivermectin as an antiviral drug, when to use steroids and the benefits of convalescent plasma, how COVID-19 affects cognitive function and the effect of long COVID and how healthcare works have difficulty making the proper diagnosis for long COVID even using a questionnaire.

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    Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) What to do when you are sick with a respiratory virus (CDC) Basis for respiratory virus guidance (CDC) Effectiveness of updated COVID-19 vaccines (MMWR) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Synergy or additive protection with vaccination and oral antivirals (CID) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Still talking about Ivermectin? (Journal of Infection) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Cognition and memory after COVID-19 (NEJM) Loss of IQ after SARS-CoV-2 infection (CIDRAP) Really, more evidence for long COVID and impaired cognition (NEJM) Memory assessment before and after COVID-19 (NEJM) Please complete this memory questionnaire (Community hyperbaric) Impact of long-term COVID-19 on workers in healthcare settings (PLoS One) Healthcare workers have difficulty assessing long COVID (CIDRAP) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1094 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV discusses effectiveness of this season’s flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery.

    Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Effectiveness of flu vaccine (MMWR, Eurosurveill) Efficacy of Pfizer RSV vaccine (Pfizer) Understanding six types of vaccine technologies (Pfizer) nOPV in US? (CDC) Dengue in Peru (Peruvian State) Measles in Michigan and Indiana Marburg virus control by reservoir bats (Nat Commun) tRNA acquisition by phages (Cell) Viruses of Microbes 2024 Timestamps by Jolene. Thanks! Weekly Picks

    Brianne – The reappearance of Lake Manly
    Kathy – “Practical Playbook for Addressing Health Misinformation”
    Rich – Making It So: A Memoir by Patrick Stewart
    Jolene – Thinking Like a Phage by Merry Youle
    Vincent – The Science of Leap Year

    Listener Picks

    Blog design – Anthony Fauci will reflect on his long government career in ‘On Call,’ to be published in June
    Peter – Republican warns of vaccines being slipped into vegetables: ‘A polio vaccine in there’

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing new vaccine guidelines released by the advisory committee on immunization practices, and reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, the role of IFN-g in long COVID, if the brain-blood-barrier is compromised in long COVID, meaning of persistent community SARS-CoV-2 RNA findings, and the effects of hyperbaric oxygen on post COVID neurocognition.

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    Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) RSV vaccination stats (CIDRAP) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) ACIP COVID vaccination for seniors recommendations (CIDRAP) Additional vaccine doses for older adults (CDC) Evidence based advice from the ACIP (CDC) State mandates did NOT influence primary vaccination rates only boosters (PNAS) No nOPV2? (CDC) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Molunpiravir plus antibody therapy for at-risk outpatients (Nat Comm) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Spontaneous release of IFN-g in Long COVID (Science Advances) Blood-brain-barrier compromise in long COVID associated cognitive impairment (Nat Neuroscience) Persistent community SARS-CoV-2 RNA (Nature) Hyberbaric oxygen therapy improves post COVID neurocognition (Scientific Reports) Medical study questionnaire, the SHORT form (Brandeis) Long term effects of hyperbaric oxygen post COVID (Scientific Reports) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1092 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews resurgence of Lassa fever in West Africa, at least 3 paralytic cases of cVDPV2 in Zimbabwe, CWD from eating prion-laden plants, measles in New Orleans and Broward County Florida, failure of Florida Surgeon General to support vaccination, a measles variant in Switzerland, SARS-CoV-2 persistent infections, leaky blood-brain-barrier for long COVID brain fog, West Nile virus transmitted among mosquitoes by the excreta, and viroid-like colonists of human microbiomes.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit and Kathy Spindler

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Resurgence of Lassa fever (Science) cVDPV2 in Zimbabwe (UNICEF) CWD from eating plants (CIDRAP) Measles in New Orleans (LA Dept Health) SARS-CoV-2 persistent infections (Nature) Leaky BBB for brain fog of long COVID (Nat Neurosci) Measles in Broward County FL (7 News) Failure of FL Surgeon General to support vaccination (X) Measles variant (Eurosurveillance) West Nile virus transmitted among mosquitos by excreta (bioRxiv) Mosquito life cycle (YouTube) Viroid-like colonists of human microbiomes (bioRxiv) Letters read on TWiV 1091 Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – Sustainable energy in America 2024 factbook
    Kathy – Life Magnified USPS stamps
    Rich – “How plants communicate with each other when in danger” by Kasha Patel (Original Nature Communications article)
    Alan – A Sargasso Sea of Space card game.
    Vincent – Tell Me When It’s Over by Paul Offit

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus before discussing uptake of the RSV vaccine Abrysvo or the monoclonal anti-RSV antibody nirsevimab to prevent severe disease following RSV infection in infants 8 months or younger before going over this week’s influenza virus and SARS-CoV-2 virus statistics, including all circulating variants in the US, examines if self-testing is more accurate than clinician administered Binax rapid diagnostic tests for SARS-CoV-2 infection, if N95 masks need a yearly fitting, how SARS-CoV-2 vaccination impacts the prevalence of long COVID, reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, why determining the exact number of long COVID incidences is challenging, how the incidence and predictors for fatiguing illness following SARS-CoV-2 infection may used to reenforce the need for public health actions to prevent virus infection and the risks of respiratory pathologies including lung cancer associate with SARS-C0V-2 infection.

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    Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) RSV vaccination stats (CIDRAP) Abrysvo vaccine stats (Axios) RSV vaccination dashboard (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Who is more accurate the clinician or the self for BinaxNow rapid testing (ASM Spectrum) Annual N95 fitting (Infection Control and Hospital Epidemiology) How vaccination impacts long COVID prevalence (Annals of Epidemiology) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID in adults (MMWR) Estimating and predicting fatiguing illness after SARS-CoV-2 infection (EIS) Long term risks of respiratory disease following SARS-CoV-2 infection (eClinical Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1080 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews a fatal Alaskapox case, MERS in Kenya, diagnostic tests for Nipah and Lassa diseases, HPV vaccination rates in the US, cases of measles in Arizona and Minnesota, hepatitis C virus-derived RNA circles in infected cells, and prevention of respiratory virus transmission by resident memory CD8+ T cells.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Fatal case of Alaskapox (AK Beacon) MERS in Kenya (Emerg Inf Dis) Diagnostic tests for Nipah and Lassa (CEPI) Measles in Arizona and Minnesota HCV-derived circular RNAs (PNAS) Resident memory CD8 T cells prevent respiratory virus transmission (Nature) Letters read on TWiV 1089 1:24:33 Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – Visualizing Science: Illustration and Beyond
    Brianne – Vaccination from the Misinformation Virus and Invisible Corps
    Alan – Preventing needlephobia in kids
    Vincent – Two new Djs I discovered Rosana Nun and Sunset Cartel

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin discusses the use of monoclonal antibody therapy to prevent RSV hospitalization of infants and use of GSK’s RSV vaccine Arexy to prevent severe disease following RSV infection in adults between 50-59 years before he reviews recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if how the influenza vaccine is manufactured can reprogram the antibody response, cardiovascular consequences of influenza infection, mortality of chikungunya virus infection, if an alternative vaccination schedule impacts the anti-SARS-CoV-2 immune response, dispels the myth that increased mortality correlated with the first vaccine dose, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how manage long COVID including prevent burnout and compassion fatigue of caring for long COVID patients, whether the CDC or WHO definition of long COVID is beneficial or the use of directed questions, baselines test and listening to the patient tell their story are beneficial in making a long COVID diagnosis.

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    Links for this episode Nirsevimab immunoprophylaxis to prevent RSV hospitalization (Eurosurveillance.) Arexvy given Priority Review in US for the prevention of RSV disease in adults aged 50-59 (GSK) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Can antibodies be redirected from egg adapted epitopes using recombinant or cell cultured based influenza vaccines (Nat) Can influenza infection lead to cardiovascular events (JID) Risk of death after chikungunya infection and disease (Lancet) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Alternative intervals between vaccine doses (Nat Comm) Early mortality after first vaccination dose (CID) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Burnout compassion fatigue Long COVID (OFID) Scoring PASC (JAMA) What is your definition of the Long COVID (WHO) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1088 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews rhinovirus complications in infants, a new influenza antiviral drug, Oropouche fever in Brazil, measles in Maryland and Ohio, effect of eliminating non-medical vaccine exemptions in NY, foot-and-mouth disease in Europe, severe primary and secondary dengue infections, and therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections.

    Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Angela Mingarelli

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Infant rhinovirus bronchiolitis contribution to hospital bed and vent use (JAMA Net Open) Onradivir new influenza antiviral (Lancet) Oropouche fever in Brazil (PAHO) Maryland and Ohio measles Repealing school vaccination exemptions (JAMA New Open) Increases risk of FMDV entry into Europe (pig333) Severe primary and secondary dengue (Nat Med) Mitigation of measles immune amnesia and exacerbated disease (Nat Comm) Letters read on TWiV 1087 Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – For Your Processing Pleasure: The Sharpest Pictures of Jupiter’s Volcanic Moon Io in a Generation
    Angela – Whale Scientists
    Rich – Benefit-risk assessment of vaccines; The Brighton collaboration standardized module for vaccine benefit-risk assessment; Vaccine adverse events: causal or coincidental?; Austin area Singing Valentines
    Vincent – International Day of Women and Girls in Science, 11 February

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market and why people conceal their infectious diseases before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if susceptibility and disease severity are inheritable traits, if vaccination during pregnancy protects neonates or leads to adverse effects, the effectiveness of a monovalent XBB.1.5 against disease resulting from infection with Omicron variants, whether vaccination in the same or opposite arms effect antibody protection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how SARS-CoV-2 infection may alter one’s sleep patterns, what the health and economic burdens of mild disease are, and if there are predictors for recovery from fatigue and cognitive deficits following SARS-CoV-2 infection.

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode Do you want a job in healthcare? (JAMA) Why people don’t tell the truth about infectious diseases (Psychological Science) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Is susceptibility and severity of COVID-19 inheritabile (Nat Comm) Neonates of vaccinated mothers (JAMA) How is the monovalent XBB.1.5 vaccine effectiveness against symptomatic infection Sept 2023-Jan 2024 (MMWR) Second dose in the opposite arm improves antibody response (JCI) Virus specific immune repsonses following contralateral or ipsilateral immunication (eBioMedicine) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) How COVID-19 affected your sleep (Frontiers in Public Health) Health and economic burden of COVID-19 after illness (BMC Medicine) Predicting recovery from fatigue and cognitive deficits after COVID-19 (eClinical Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1086 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews measles outbreaks in England and Europe, 2 fatal Nipah virus cases in Bangladesh, yellow fever outbreak in Sudan, and discuss how the type of immunodeficiency influences the outcome of SARS-CoV-2 infection, and programming of alveolar macrophages by intestinal bacteria that influences severity of respiratory viral infection.

    Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Pig virus imperils food security in Borneo (Science) Measles outbreaks in UK and Europe (Nature) Fatal Nipah virus infections in Bangladesh (CIDRAP) Yellow fever outbreak in Sudan (Crisis24) COVID-19 influenced by type of immunodeficiency (Sci Transl Med) Intestinal microbiota programming of alveolar macrophages (Cell Host Microbe) Letters read on TWiV 1085 Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – JWST details of 19 spiral galactic centers
    Rich – Great White Shark Attack And Breach
    Vincent – Black History Month and Lost Photographs of Black America

    Listener Picks

    Louise – The Mystery Of The Village That Beat The Black Death
    Pierre – Three things airlines don’t want you to know
    Brandon – Professor Dave explains

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses the safety of the prefusion RSV vaccine, if high or moderate dose of the quadrivalent influenza vaccine is better for protection against hospitalization, summarizes the new WHO COVID guidelines, revisits how to prevent pathogen transmission in healthcare setting, the under use of COVID oral antiviral and what occurs in persistently SARS-CoV-2 infected cells in culture after antiviral treatment, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how inflammatory markers change correlate with death when in ICU and if cognitive slowing is part of long COVID-19.

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode Do you want a job in healthcare? (JAMA) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Efficacy and safety of RSV vaccine after 2 seasons (CID) High vs moderate dose of quadrivalent influenza vaccine (CMI) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) WHO COVID guidance (WHO) Thoughts on COVID guidance (CIDRAP) Update on how to prevent pathogen transmission in healthcare settings (CDC) Underuse of antiviral drugs against COVID-19 (MMWR) Revisiting tissue culture cells persistently infected following antiviral therapy (bioRxiv) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Changes in inflammatory markers and death correlation when in ICU (Cytokine) Long COVID & cognitive slowing? (eClinicalMedicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1084 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]

  • TWiV reviews global measles outbreaks, toilet-generated aerosols that spread viruses, highly effective prevention of invasive cervical cancer by HPV vaccination, and design of improved adenovirus-associated viral vectors using machine learning.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Jay Nelson obituary Measles outbreak in Europe and Central Asia (UNICEF) Closing the toilet lid doesn’t reduce virus aerosols (Am J Inf Control) NASA’s ingenuity helicopter mission ends (NASA) HPV vaccine prevents invasive cervical cancer (J NCI) Designing AAV vectors with machine learning (Sci Adv) Letters read on TWiV 1083 Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – Asian girl building a life building a fence to protect a bamboo house
    Rich – Gator Country: Deception, Danger, and Alligators in the Everglades by Rebecca Renner
    Alan – Strange Bedfellows, by Ina Park
    Vincent – Star and Sphere kit – try the main page too

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, before discussing viral transmission to adults in healthcare setting, the recently EUA approved protein based COBREVAX vaccine, reviews quarantine guidelines, the use of simnotrelivr for mild to moderate COVID-19, how viral RNA may persist in your cell culture dish following antiviral therapy, continues to dispel the myth of viral rebound, how to pay for Paxlovid, , when to use steroids and the benefits of convalescent plasma, how Paxlovid may prevent long COVID and how complement dysfunction may lead to thromboinflammation during long COVID.

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    Links for this episode Articles and graphs cited in TWIV CU 1080 Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Transmission in healthcare setting (CID) COBREVAX EUA (Texas Children’s Hospital) Quarantine/isolation guidelines (CDC) Simnotrelvir for mild to moderate disease in adults (NEJM) Are your tissue culture cells persistently infected following antiviral therapy (bioRxiv) Structural biology of antivirals for SARS-CoV-2 (Signal Tranduction and Targeted Therapy) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Remdesivir for immunocompromised during variant waves (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Patients, experts, Congress…..long COVID oh my! (CIDRAP) Does paxlovid prevent long COVID? (CIDRAP) Persistent complement with thromboinflammation in long COVID (Science) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1082 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

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  • TWiV reviews the latest virology news, how infection with a plant virus causes insect to grow long wings, and reverse zoonoses of 2009 H1N1 pandemic influenza viruses in US swine.

    Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Brianne Barker, and Angela Mingarelli

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    Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Midwife gave children pellets instead of vaccines (NY Times) Vaccine derived poliovirus circulation in Indonesia (WHO) 9th case of measles in Philadelphia (City of Philadelphia) Measles exposure warning northern Virginia (Virginia DOH) China lab sequenced SARS-CoV-2 genome 2 weeks before release (WSJ) Wisconsin bill to restrict gain of function experiments (Science) Virus infection of insects causes long wings (PNAS) Reverse zoonoses of influenza H1N1 virus in swine (PLoS Path) Timestamps by Jolene. Thanks! Weekly Picks

    Dickson – Concerto for Horn and Hardart, P. Schickele
    Angela – ChatGPT4
    Brianne – How mRNA Vaccine Works, Why We Need Two Doses of mRNA Vaccine
    Rich – Evolutionary basis for the human diet: consequences for human health by P. Andrews, R.J. Johnson
    Vincent – Virology Lectures 2024

    Listener Picks

    Geoff and Anonymous – Dickson Despommier wants our cities to be like forests

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to [email protected]

  • In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing vaccine effectiveness in children and adolescents, how the pandemic impacted the socioemotional development of infants and toddlers, continues to dispel the myth of viral rebound, how to pay for Paxlovid, reviews quarantine guidelines, when to use steroids and the benefits of convalescent plasma, examines the role of immune aberrations in long COVID and how vaccination may protect against developing long COVID.

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    Become a patron of TWiV!

    Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend(CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Remember when COVID was bad? (Wired) Children and adolescents hospitalized with SARI (Pediatrics) COVID-19 vaccines are effective for adolescents (Pediatrics) Vaccine effectiveness against long COVID in children (Pediatrics) Infant and toddler socioemotional development in the pandemic (JAMA) Quarantine/isolation guidelines (CDC) Should I take Paxlovid? (NY Times) What is this about Paxlovid rebound? (CDC) Rebound is NOT the early inflammatory phase (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) T cell dysregulation inflammation and uncoordinated adaptive immune response, Long COVID oh my (Nat Imm) Vaccine effectiveness against long COVID (CIDRAP) Prevention of long COVID by vaccines (Antimicrobial-stewardship and healthcare) Sex and gender relationship with long COVID (Eurosurveillance) Are all vaccines equal in preventing Long COVID? (Lancet) Vaccine naïve individuals, Long COVID and vaccination (medRxiv) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1080 Dr. Griffin’s COVID treatment summary (pdf) Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your questions for Dr. Griffin to [email protected]