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While memory loss is generally thought of as the hallmark of dementia, behavioral and psychological symptoms of dementia like agitation, aggression, anxiety, and hallucinations are nearly universal, affecting almost all patients with advanced dementia. These behavioral disturbances are often the trigger for nursing home placement, and they can be highly distressing for both patients and their care partners. In today’s episode, Matt and Lauren speak with Dr. Ellen McCreedy, a researcher from the Brown School of Public Health who has conducted a study of personalized music intervention called Music & Memory for people living with dementia in nursing homes. Dr. McCreedy is a gerontologist and health services researcher who focuses on evaluation of non-pharmacologic interventions for managing behavioral disturbances of people living with dementia.
Ellen McCreedy, PhD, MPH Faculty Profile
Articles from Episode:
Sisti A, Gutman R, Mor V, Dionne L, Rudolph JL, Baier RR, McCreedy EM. Using Structured Observations to Evaluate the Effects of a Personalized Music Intervention on Agitated Behaviors and Mood in Nursing Home Residents With Dementia: Results From an Embedded, Pragmatic Randomized Controlled Trial. Am J Geriatr Psychiatry. 2024 Mar;32(3):300-311. doi: 10.1016/j.jagp.2023.10.016. Epub 2023 Nov 2. PMID: 37973488; PMCID: PMC10922136.
McCreedy EM, Gutman R, Baier R, Rudolph JL, Thomas KS, Dvorchak F, Uth R, Ogarek J, Mor V. Measuring the effects of a personalized music intervention on agitated behaviors among nursing home residents with dementia: design features for cluster-randomized adaptive trial. Trials. 2021 Oct 7;22(1):681. doi: 10.1186/s13063-021-05620-y. PMID: 34620193; PMCID: PMC8496617.
The transcript for this episode can be found here.
You can subscribe to Minding Memory on Apple Podcasts, Spotify, or wherever you listen to podcasts.
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In this episode, Matt & Lauren speak with Dr. Lianlian Lei, an Assistant Professor in the Department of Psychiatry at the University of Michigan. Dr. Lei discusses a recent study that looks at the impact of partner’s plan choice on the likelihood of Medicare Advantage disenrollment and how that may impact older adults living with dementia. Unlike traditional Medicare that's administered by the federal government, Medicare Advantage are healthcare plans that are administered by private health insurance companies. These plans can vary a lot and typically cover additional services not covered by traditional Medicare. Navigating the various plan options can be a challenge for older adults, and it's not uncommon for individuals to change plans depending on their current needs.
Dr. Lianlian Lei Faculty Profile
Article from Episode: Lei L, Levy H, Ankuda C, Hoffman GJ, Kim HM, Strominger J, Maust DT. Partner Plan Choices and Medicare Advantage Enrollment Decisions Among Older Adults. JAMA. 2024 Mar 20:e241773. doi: 10.1001/jama.2024.1773. Epub ahead of print. PMID: 38506841; PMCID: PMC10955388.
The transcript for this episode can be found here.
You can subscribe to Minding Memory on Apple Podcasts, Spotify, or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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Saknas det avsnitt?
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In this episode, Lauren and Matt talk with Leah Richmond-Rakerd, PhD who is an Assistant Professor in the Department of Psychology at the University of Michigan. Her research focuses on emotional and behavioral dysregulation across the life course. Here, Dr. Richmond-Rakerd will discuss her recent study on “The Associations of Hospital-Treated Infections with Subsequent Dementia: Nationwide 30-year Analysis” that was published in Nature Aging.
Articles Discussed in Episode:
Richmond-Rakerd LS, Iyer MT, D'Souza S, Khalifeh L, Caspi A, Moffitt TE, Milne BJ. Associations of hospital-treated infections with subsequent dementia: nationwide 30-year analysis. Nat Aging. 2024 Jun;4(6):783-790. doi: 10.1038/s43587-024-00621-3. Epub 2024 May 7. PMID: 38714911.
Milne BJ, Atkinson J, Blakely T, Day H, Douwes J, Gibb S, Nicolson M, Shackleton N, Sporle A, Teng A. Data Resource Profile: The New Zealand Integrated Data Infrastructure (IDI). Int J Epidemiol. 2019 Jun 1;48(3):677-677e. doi: 10.1093/ije/dyz014. Erratum in: Int J Epidemiol. 2019 Jun 1;48(3):1027. doi: 10.1093/ije/dyz054. PMID: 30793742.
NZ Integrated Data Infrastructure: https://www.stats.govt.nz/integrated-data/integrated-data-infrastructure/
Visit the Center to Accelerate Population Research in Alzheimer's (CAPRA) website to learn more.
The transcript for this episode can be found here.
You can subscribe to Minding Memory on Apple Podcasts, Spotify, or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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Welcome to Season 4 of Minding Memory, where we are welcoming a new co-host, Lauren Gerlach to the Minding Memory team. Lauren is a Geriatric Psychiatrist at the University of Michigan and a member of the CAPRA leadership team. In this episode, Lauren shares a little background on her research interests, what it’s like to be a geriatric psychiatrist, and some lessons learned about using “uncool” emoticons or emojis when texting.
The transcript for this episode can be found here.
You can subscribe to Minding Memory on Apple Podcasts, Spotify, or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode, Matt and Donovan talk with Dr. Jason H. Moore, Director of the Center for Artificial Intelligence Research and Education (CAIRE) and Chair of the Department of Computational Biomedicine at Cedars-Sinai Medical Center. Jason discusses the coming impact of artificial intelligence on a spectrum of Alzheimer’s disease and related dementia (ADRD) issues. We discuss how tools such as AI-powered chatbots may improve quality of life for people living with dementia (and their caregivers) and how AI may contribute in the future to diagnosis and treatment.
Faculty Bio: https://researchers.cedars-sinai.edu/Jason.Moore
Center for Artificial Intelligence Research and Education (CAIRE): https://www.cedars-sinai.edu/research/areas/caire.html
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Minding Memory, Matt & Donovan speak with Dr. Joanne Spetz, the Brenda and Jeffrey L. Kang Presidential Chair in Healthcare Finance and Director of the Philip R. Lee Institute for Health Policy Studies at the University of California, San Francisco (UCSF). Joanne talks with Matt & Donovan about who makes up the professional workforce of people who provide dementia care and how these individuals play a critical role in the delivery of services. Joanne also discusses how different professional roles interact across setting of care. Lastly, Joanne introduces a new study she is working on with Donovan called the National Dementia Workforce Study (NDWS) that will be surveying a large group of clinicians who provide care for people living with dementia.
Faculty Bio: https://profiles.ucsf.edu/joanne.spetz
Article Referenced in Podcast:
Candon M, Bergman A, Rose A, Song H, David G, Spetz J. The Relationship Between Scope of Practice Laws for Task Delegation and Nurse Turnover in Home Health. J Am Med Dir Assoc. 2023 Nov;24(11):1773-1778.e2. doi: 10.1016/j.jamda.2023.07.023. Epub 2023 Aug 24. PMID: 37634547; PMCID: PMC10735229.
Previous Minding Memory Episodes on Dementia & Family Caregiving:
S1Ep9: Caregiving for individuals with Dementia (with Amanda Leggett)
S1Ep10: What is it like to be a Caregiver for a Person Living with Dementia? (with Peggy Arden)
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Minding Memory, Matt & Donovan speak with Dr. Lisa Barnes, the Alla V. and Solomon Jesmer Professor of Gerontology and Geriatric Medicine, Department of Neurological Sciences and Associate-Director of the Rush Alzheimer’s Disease Center at Rush University. Dr. Barnes talks with Matt & Donovan about racial disparities in Alzheimer’s disease dementia and several obstacles that have impeded our understanding of race and dementia.
Faculty Profile: https://www.rushu.rush.edu/faculty/lisa-barnes-phd
RADC Resource Sharing Hub: https://www.radc.rush.edu/
Article Referenced in Podcast:
Barnes LL. Alzheimer disease in African American individuals: increased incidence or not enough data? Nat Rev Neurol. 2022 Jan;18(1):56-62. doi: 10.1038/s41582-021-00589-3. Epub 2021 Dec 6. PMID: 34873310; PMCID: PMC8647782.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In 2009, the Health Information Technology for Economic and Clinical Health Act, wow, that's a mouthful, more commonly known as the HITECH Act, spent billions to promote the uptake of electronic health records by US hospitals. Fast forward more than a decade later, and now approximately four out of five healthcare institutions have electronic health record systems in place that integrate clinical notes, test results, medications, diagnostic images, et cetera. The adoption of EHR systems into healthcare introduces new and exciting opportunities to extract information that can be used to augment other types of data for research. As you might imagine though, it can be tricky to pull out meaningful information from the text of clinical notes. In this episode, we'll speak with a University of Michigan researcher, Dr. Vinod Vydiswaran, who's been developing methods to identify dementia from EHR data.
Faculty Profile: https://medicine.umich.edu/dept/lhs/vg-vinod-vydiswaran-phd
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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The population of older adults living with dementia is expected to swell to nearly 14 million by 2050 and is estimated to cost the US economy more than 500 billion each year. In the absence of a cure for Alzheimer's disease, the primary cause of dementia, there's interest in understanding modifiable risk factors. In theory, getting a handle on the modifiable risk factors for dementia, would enable public health efforts to reduce cognitive decline in dementia at the population level. We've come a long way in understanding the risk factors for Alzheimer's disease and other related dementias. However, there's still work to be done. In this episode, we'll speak with Dr. Josh Ehrlich, a researcher at the University of Michigan, who has examined vision impairment as a risk factor for dementia.
Joshua Ehrlich Faculty Profile: https://medicine.umich.edu/dept/ophthalmology/joshua-r-ehrlich-md-mph
Articles Referenced in the Podcast:
Ehrlich JR, Goldstein J, Swenor BK, Whitson H, Langa KM, Veliz P. Addition of Vision Impairment to a Life-Course Model of Potentially Modifiable Dementia Risk Factors in the US. JAMA Neurol. 2022 Jun 1;79(6):623-626. doi: 10.1001/jamaneurol.2022.0723. Erratum in: JAMA Neurol. 2022 Jun 1;79(6):634. PMID: 35467745; PMCID: PMC9039828.
New York Times Article, July 2022: New Dementia Prevention Method May Be Behavioral, Not Prescribed
Lancet Commission on Dementia Prevention, Intervention, and Care (2020)
Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG, Dias A, Fox N, Gitlin LN, Howard R, Kales HC, Kivimäki M, Larson EB, Ogunniyi A, Orgeta V, Ritchie K, Rockwood K, Sampson EL, Samus Q, Schneider LS, Selbæk G, Teri L, Mukadam N. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020 Aug 8;396(10248):413-446. doi: 10.1016/S0140-6736(20)30367-6. Epub 2020 Jul 30. Erratum in: Lancet. 2023 Sep 30;402(10408):1132. PMID: 32738937; PMCID: PMC7392084.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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According to an estimate published in 2015, the global prevalence of dementia was projected to nearly triple between 2015 and 2050, growing from 46 million to over 130 million people globally. And of that worldwide share, 70% of those with dementia will be in low- and middle-income countries. Tackling and ideally preventing dementia requires a global perspective. In this episode, Matt & Donovan speak with Dr. Lindsay Kobayashi, a faculty member in the Department of Epidemiology at the University of Michigan School of Public Health whose research focuses on the social epidemiology of aging from a global perspective. Dr. Kobayashi introduces us to a whole new world of data available to help researchers tackle dementia as a global challenge.
Lindsay Kobayashi Faculty Profile: https://sph.umich.edu/faculty-profiles/kobayashi-lindsay.html
Article referenced in this episode:
Kobayashi LC, Gross AL, Gibbons LE, Tommet D, Sanders RE, Choi SE, Mukherjee S, Glymour M, Manly JJ, Berkman LF, Crane PK, Mungas DM, Jones RN. You Say Tomato, I Say Radish: Can Brief Cognitive Assessments in the U.S. Health Retirement Study Be Harmonized With Its International Partner Studies? J Gerontol B Psychol Sci Soc Sci. 2021 Oct 30;76(9):1767-1776. doi: 10.1093/geronb/gbaa205. PMID: 33249448; PMCID: PMC8557836.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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Over thirty percent of individuals living with dementia living in the US each year die either of or with dementia – and almost half of those enrolled in hospice have dementia. As with so many other types of healthcare, there are disparities in both who enrolls in hospice as well as the type of care these individuals receive after enrollment. In this episode, Matt & Donovan talk with Dr. Lauren Hunt from UCSF, an expert in hospice care for persons living with dementia, about dementia at the end of life.
Lauren Hunt Faculty Profile: https://profiles.ucsf.edu/lauren.hunt
Article referenced in this episode:
Hunt LJ, Gan S, Smith AK, Aldridge MD, Boscardin WJ, Harrison KL, James JE, Lee AK, Yaffe K. Hospice Quality, Race, and Disenrollment in Hospice Enrollees With Dementia. J Palliat Med. 2023 Aug;26(8):1100-1108. doi: 10.1089/jpm.2023.0011. Epub 2023 Apr 3. PMID: 37010377; PMCID: PMC10440673.
Article on identifying disenrollment in claims data:
Hunt LJ, Gan S, Boscardin WJ, Yaffe K, Ritchie CS, Aldridge MD, Smith AK. A national study of disenrollment from hospice among people with dementia. J Am Geriatr Soc. 2022 Oct;70(10):2858-2870. doi: 10.1111/jgs.17912. Epub 2022 Jun 7. PMID: 35670444; PMCID: PMC9588572.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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Extreme weather and weather-related disasters are becoming more and more common. Unfortunately, disaster related disruptions in healthcare tend to affect the most vulnerable of populations – including older adults living with cognitive impairment. In this episode, Matt & Donovan speak with University of Michigan faculty member, Sue Anne Bell, about how healthcare disruption due to a disaster can affect the population of older adults living with dementia.
Sue Anne Bell Faculty Link: https://nursing.umich.edu/faculty-staff/faculty/sue-anne-bell
Article referenced in podcast:
Bell SA, Miranda ML, Bynum JPW, Davis MA. Mortality After Exposure to a Hurricane Among Older Adults Living With Dementia. JAMA Network Open. 2023 Mar 1;6(3):e232043. doi: 10.1001/jamanetworkopen.2023.2043. PMID: 36881412; PMCID: PMC9993175.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Minding Memory, we dive into the newest FDA-approved drug to treat Alzheimer’s – Lecanemab – with Ohio State University stroke neurologist Jim Burke. Dr. Burke discusses the benefits and drawbacks of the new Alzheimer’s drug and also the paradigm shift of how people (clinicians, patients, and the general population) are thinking about these news Alzheimer’s medications.
Jim Burke Faculty Profile: https://wexnermedical.osu.edu/find-a-doctor/james-burke-md-128794
Article referenced in podcast: Burke JF, Richard S, Langa KM, Albin RL, Kotagal V. Lecanemab: Looking Before We Leap. Neurology. 2023 Jul 21: doi: 10.1212/WNL.0000000000207505. Epub ahead of print. PMID: 37479527.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode, Donovan & Matt talk with health services researcher Betsy White from Brown University about a unique new resource for researchers called the Long-Term Data Cooperative, a provider-led data sharing collaboratory that puts together nursing home EHR data from EHR vendors that can be linked to Medicare claims. This powerful tool is made available to researchers through an online application process.
This episode references the RFA for the Real-World Data Scholars Program, which is now expired. However, Minding Memory listeners can find out about upcoming opportunities or future RFAs by emailing [email protected].
Betsy White Faculty Profile: https://vivo.brown.edu/display/ewhite14
Long Term Care Data Cooperative: https://www.ltcdatacooperative.org/Pages/default.aspx
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode, Matt & Donovan speak with University of Michigan School of Public Health Professor, Dr. J. Scott Roberts, who investigates the psychological and behavioral impact of genetic risk disclosure for Alzheimer's disease.
In addition to being a professor in the Health Behavior & Health Education department at the School of Public Health, Dr. Roberts is also a core lead of the Michigan Alzheimer’s Disease Center. Dr. Roberts’s research interests focus on the process and impact of risk assessment and disclosure for adult-onset disorders, as well as the ethical, legal, and social implications of advances in genomic science & technology.
Faculty Profile: https://sph.umich.edu/faculty-profiles/roberts-j.html
Michigan Alzheimer’s Disease Center (MDAC): https://alzheimers.med.umich.edu/
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode, Matt & Donovan speak with a health economist, Dr. Lauren Nicholas, whose research investigates how missing a single credit card payment may be a very early indicator of a cognitive issue. Dr. Nicholas is an associate professor in the department of Health Systems Management & Policy at the University of Colorado School of Public Health and has published several studies that examined on how a financial issue might be among the first signs of cognitive decline.
Lauren Nicholas Faculty Profile: https://coloradosph.cuanschutz.edu/resources/directory/directory-profile/Nicholas-Lauren-UCD6003780837
Article referenced in this episode:
Nicholas LH, Langa KM, Bynum JPW, Hsu JW. Financial Presentation of Alzheimer Disease and Related Dementias [published correction appears in JAMA Intern Med. 2021 Feb 1;181(2):296]. JAMA Intern Med. 2021;181(2):220-227. doi:10.1001/jamainternmed.2020.6432
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode, Donovan & Matt speak with Geoffrey Hoffman, a faculty member and researcher at the University of Michigan School of Nursing. Dr. Hoffman discusses the transition to the role of caregiver for partners of persons diagnosed with dementia – and the unique emotional burden and stress that they undertake. Dr. Hoffman also discusses using the Health & Retirement Study (HRS) to better explore the emotional stress and onset of depression in caregivers.
Geoff Hoffman Faculty Profile: https://nursing.umich.edu/faculty-staff/faculty/geoffrey-j-hoffman
Article Referenced in this Episode
Harris ML, Errickson J, Ha J, Hoffman GJ. Depressive Symptoms and Caregiving Intensity Before and After Onset of Dementia in Partners: A Retrospective, Observational Study. Med Care. 2022;60(11):844-851. doi:10.1097/MLR.0000000000001771 [PMID: 36038513]
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode we’ll speak with Dr. Julie Bynum who was the senior author on a recent study that examined how the likelihood of receiving a diagnosis of dementia has changed over the last decade or so. We’ll discuss what this might mean clinically and what researchers that rely on Medicare data should take-away from this finding. We also will talk in general about the various approaches that exist for identification of dementia in Medicare billing data.
Julie Bynum Faculty Profile: https://medicine.umich.edu/dept/dgpm/julie-bynum-md-mph
Article Referenced in this Episode
Davis MA, Chang CH, Simonton S, Bynum JPW. Trends in US Medicare Decedents' Diagnosis of Dementia From 2004 to 2017. JAMA Health Forum. 2022 Apr 1;3(4):e220346. doi: 10.1001/jamahealthforum.2022.0346. PMID: 35977316
Resources:
The Bynum-Standard 1-Year Algorithm for identifying Alzheimer’s Disease and Related Dementias (ADRD) in Medicare Claims data.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode we discuss what’s known about the association between personality type and cognitive function. Further, the idea of resilience—or what protects the cognition of individuals with a high level of neuropathology associated with cognitive decline—might have important implications for dementia prevention. Our guests are Dr. Eileen Graham and Dr. Dan Mroczek. Drs. Graham and Mroczek are both faculty at Northwestern University with interests in how personality factors influence physical and cognitive health over the life course.
Eileen Graham Faculty Profile
Dan Mroczek Faculty Profile
Article References in Podcast:
Graham EK, James BD, Jackson KL, et al. Associations Between Personality Traits and Cognitive Resilience in Older Adults. J Gerontol B Psychol Sci Soc Sci. 2021;76(1):6-19. doi:10.1093/geronb/gbaa135
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
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Health data analysts are an elusive bunch in the wild. While we see their names periodically show up as middle authors on manuscripts or in the Acknowledgement section they work largely behind the scenes; yet they play a vital role in conducting research that use large data. In this episode we speak with several health data analysts to better understand the role they play in research and, for all the researchers out there, discuss how to make the process as smooth as possible when working with an analyst.
The transcript for this episode can be found here.
CAPRA Website: http://capra.med.umich.edu/
You can subscribe to Minding Memory on Apple Podcasts, Spotify, Google Podcasts or wherever you listen to podcasts.
Hosted on Acast. See acast.com/privacy for more information.
- Visa fler