Avsnitt
-
On this special episode of JHLT: The Podcast, the Digital Media Editors take a look back at the exciting science that was on display at ISHLT2025, the ISHLT 45th Annual Meeting & Scientific Sessions.
Topics include:
Telomere biology disorders and lung transplantation The meeting's special focus on cardiogenic shock The apixiVAD trial exploring low dose apixaban in HeartMate 3 LVADs Myocardial recovery on durable LVADsFor the latest studies from JHLT, visit jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at ishlt.org/jhlt. Full-text abstracts of the meeting can also be found at the JHLT website.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Peter Cho and senior author Abbas Ardehali, MD, to discuss the paper, “Severe primary graft dysfunction in heart transplant recipients using donor hearts after circulatory death: a United States Experience.”
Peter is a third year medical student at Drexel University, and Dr. Ardehali is professor of surgery and medicine and the Director of the Heart, Lung, and Heart-Lung Transplant programs at UCLA.
The episode explores:
The study's findings regarding an increased incidence of severe PGD at 24 hours post-transplant in DCD over DBD recipients What risks weren't changed in DCD recipients—suggesting that DCD PGD is likely to be transient, and may have a different phenotype How NRP may impact the outcomes Mitigating the risk of PGDFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Tune in again later this month for the Digital Media Editors’ findings and observations from the ISHLT2025 Annual Meeting in Boston.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
Saknas det avsnitt?
-
Returning for a second study this month, the JHLT Digital Media Editors invite first author Charlotte Van Edom to discuss the paper, “Apixaban plasma levels in patients with HeartMate 3 support.”
As a cardiologist in training and a PhD candidate at the University Hospitals Leuven in Belgium, Van Edom’s work focuses on hemocompatibility and mechanical circulatory support, covering both short-term and long-term support.
The episode explores:
The evolution of the use and understanding of direct oral anticoagulants (DOACs) during LVAD support, including the increased focus on Factor Xa inhibitors Encouraging findings from the study and what clinical practices might need to change if introducing apixaban Additional studies exploring DOACs in LVAD patientsFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Treat or research pulmonary vascular diseases? Check out the first April episode for a study on sotatercept in PAH patients.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Ioana Preston, MD, to discuss the paper, “Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR.”
Dr. Preston is the director of the pulmonary hypertension center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and has over 20 years of experience in caring for patients with PH, as well as multiple clinical trials in PH.
The episode explores:
What makes sotatercept unique as the first “biologic” in the treatment of PAH Hypotheses about the mechanism of action in sotatercept Sotatercept’s interaction with mPAP and what it indicates about the drug’s action on the pulmonary vasculatureFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those involved in the heart failure and mechanical circulatory support should tune in again later this month for a study on apixaban plasma levels in patients with HeartMate 3 support.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
Returning for a second study this month, the JHLT Digital Media Editors conduct an internal discussion on the paper, “Safety and efficacy of riociguat in patients with pulmonary arterial hypertension and cardiometabolic comorbidities: Data from interventional clinical trials.”
The episode explores:
The aging PAH population and the new comorbidities that must be considered in research How the study augments and expands on recent standards, like the 2022 ESC/ERS guidelines for pulmonary hypertension Limitations on the study and opportunities for future researchFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those on lung transplant teams should check the previous episode for a study on how rewarming ischemia time affects lung transplant outcomes.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jan Van Slambrouck, MD, to discuss the paper, “The effect of rewarming ischemia on tissue transcriptome and metabolome signatures: A clinical observational study in lung transplantation.”
Dr. Van Slambrouck is a general surgeon who’s just finished his PhD training at the KU Leuven lab of respiratory disease and thoracic surgery in Belgium.
The episode explores:
How rewarming ischemia time (RIT) affects donor lungs, especially on the molecular level The pace of rewarming and how prior literature prepared the team to track and evaluate it Clinical strategies to reduce RIT and directly address molecular changesFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those involved in the pulmonary vascular disease space should tune in again later this month for a study on the safety and efficacy of riociguat in patients with PAH.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
Returning for a second study this month, the JHLT Digital Media Editors invite lead author Oliver J.F. Weiner, to discuss the paper, “Sympathetic reinnervation in cardiac transplant recipients: Prevalence, time course, and association with long-term survival.”
Dr. Weiner is currently an out of training registrar at Monash Health in Melbourne, Australia, but will soon return to his home of the UK to begin internal medicine training with the intention becoming a cardiologist. He is especially interested in advanced heart failure and electrophysiology.
The episode explores:
The uncertainty around clinical influences on reinnervation The importance of this single-center study in expanding the literature Potential future treatment optionsFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those on lung transplant teams should check the previous episode for a study on recent trends and post-transplant outcomes from EVLP.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Jonathan E. Williams, MD, to discuss the paper, “Ex-Vivo Lung Perfusion: National Trends and Post-Transplant Outcomes.”
Dr. Williams is a general surgery resident at the University of Michigan in Ann Arbor, with work focusing on contemporary lung preservation strategies, perfusion techniques, and particularly, EVLP.
The episode explores:
How the study explores the theory that EVLP use may increase transplant volumes Preserving data quality and other study limitations How to work in fields of study that sometimes yield as many questions as answersFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those on heart transplant teams should tune in again later this month for a study on sympathetic reinnervation in cardiac transplant recipients.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
JHLT: The Podcast returns with a year-end recap of 2024. Each Digital Media Editor shares one of their favorite studies from JHLT in 2024 for a quick recap of last year’s excellent science in advanced heart and lung disease.
Studies featured:
· Cardiac magnetic resonance assessment of acute rejection and cardiac allograft vasculopathy in pediatric heart transplant
Kikano, Sandra et al. JHLT May 2024 5(43):745-754· A modular simulation framework for organ allocation
Rose, Johnie et al. JHLT Aug 2024 8(43):1326-1335.· HeartMate 3 Snoopy: Noninvasive cardiovascular diagnosis of patients with fully magnetically levitated blood pumps during echocardiographic speed ramp tests and Valsalva maneuvers
Schlöglhofer, Thomas et al. JHLT Feb 2024 2(43):251-260.· Factors associated with acute limb ischemia in cardiogenic shock and downstream clinical outcomes: Insights from the Cardiogenic Shock Working Group
Kochar, Ajar et al. JHLT Nov 2024 11(43):1846-1856.For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
Happy new year from JHLT: The Podcast! On this episode, the Digital Media Editors are joined by ISHLT Director of Marketing + Communications Jess Burke, CAE, to share a little bit about themselves and their backgrounds.
Hear about how each of the JHLT Digital Media Editors got involved in transplantation and a little about each of their research and personal interests.
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don’t already get the Journal? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On the second December episode of JHLT: The Podcast, the Digital Media Editors explore another paper from the December issue of JHLT, entitled “Long-term follow-up of the randomized, prospective Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE) trial.”
First author Entela Bollano, MD, PhD, and senior author Niklas Bergh, MD, PhD, both from the Sahlgrenska University Hospital in Sweden, join the podcast to discuss their work.
You’ll hear about:
Past outcomes of the SCHEDULE trial, including reduced CAV in patients on everolimus over patients on CNIs How this study filled the need for long-term follow up on randomized studies on immunosuppression Limitations of the study, and what additional follow up might teach usFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Lung clinicians: if you haven’t yet tuned in for the first episode from this month, check it out! The paper discusses the effects of pollution post lung transplantation.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors invite lead author Chung-Wai Chow, MD, PhD, FRCPC, to discuss the paper, “Pollution exposure in the first 3 months post transplant is associated with lower baseline FEV1 and higher CLAD risk.”
Dr. Chow is a transplant pulmonologist and clinician scientist at the University of Toronto, with work focusing on investigating air pollution’s impact on chronic lung diseases and developing improved methods to assess lung function.
The episode explores:
Measurement methods for home and personal air pollution exposures Specific pollutants like black carbon and their effects on patients after lung transplant Practical advice for mitigating these effectsFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Those on heart transplant teams should tune in again later this month for a Scandinavian study that performs long-term follow ups with patients on the nephrotoxic effects of CNIs.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On the second November episode of JHLT: The Podcast, the Digital Media Editors continue MCS-month with a paper from the November issue of JHLT, entitled “Aortic insufficiency in the patient on contemporary durable left ventricular assist device support: A state-of-the-art review on perioperative and postoperative assessment and management.”
First author Diyar Saeed, MD, PhD, of the Heart Center Niderrhein, and senior author Jennifer Cowger, MD, MS, of Henry Ford Hospitals both join the podcast.
You’ll hear about:
Why LVAD patients develop new and progressive aortic regurgitation—and how contemporary devices may differ Associated hemodynamic events Intraoperative surgical techniques Slowing the progression of the condition and monitoring it post-op Early interventionsFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
If you haven’t yet tuned in for the first November episode of the podcast, MCS enthusiasts will be happy to know the paper discusses temporary MCS devices in acute RV failure.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors have three expert guests to discuss their paper, “Pragmatic approach to temporary mechanical circulatory support in acute right ventricular failure.”
You’ll hear from first author Anthony Carnicelli, MD, from the Medical University of South Carolina; Alexander Bernhardt, MD, from the University Hospital Hamburg-Eppendorf; and senior author Manreet Kanwar, MD, of the Cardiovascular Institute at Allegheny Health Network.
The episode explores:
Parameters that influence deciding when to escalate RV support Determining which device is right for each patient Evaluating a patient for the correct anticoagulants Device-related complications and solutions What's next in research for tMCS and acute RV failureFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Join us again later this month for another MCS study, exploring aortic insufficiency in patients with durable LVADs.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the October issue of JHLT, entitled “Donor to recipient age matching in lung transplantation: A European experience.” Senior author Andrew Fisher, FRCP, PhD joins the podcast to discuss the paper.
You’ll hear about:
European practices in lung transplantation and the donor population Main findings and takeaways How age disparities in donor matching affect outcomes Extended criteria for older donorsFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
If you haven’t yet tuned in for the first October episode of the podcast, scroll back in the episode history for the latest ISHLT guideline on the evaluation and care of cardiac transplant candidates.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the Digital Media Editors discuss a new guidelines document from the ISHLT entitled “The 2024 ISHLT Guidelines for the Evaluation and Care of Cardiac Transplant Candidates.”
The lead co-authors of the document—Yael Peled, MD, and Anique Ducharme, MD, MSc—are on the podcast to discuss the document.
You’ll hear about:
Challenges in drafting such an overarching document Highlights for clinicians Major changes in the document since the last version How changes in durable and temporary MCS affect use of the documentFor the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Join us again later this month for a study on age matching in lung transplantation.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
This month, JHLT: The Podcast reissues our September 2023 tribute to former Editor-in-Chief, Dr. Daniel R. Goldstein. Dr. Goldstein stepped down from his role for health reasons in July 2023; he had been diagnosed with an advanced salivary gland malignancy and felt he would be unable to continue serving JHLT and the International Society for Heart and Lung Transplantation (ISHLT) to his characteristically demanding standard.
Sadly, Dr. Goldstein died on 21 May, 2024, at the age of 56, leaving behind his wife, 2 children, an extended family, and a larger universe of colleagues, collaborators, and mentees who greatly benefited from his equanimity, wisdom, and commitment to his passions.
The tribute, recorded in August 2023, features Michelle Kittleson, MD, PhD, then-Interim Editor-in-Chief of JHLT; Andrew Gelman, PhD, Deputy Editor at JHLT; Andrew Fisher, FRCP, PhD, past president of ISHLT and Past Chair of the Publications Oversight Committee; Daniel Tyrrell, PhD, a former post-doc of Dr. Goldstein’s; and Judy Chen, PhD, a former immunology PhD student in Dr. Goldstein’s lab.
Two funds were created to allow friends and colleagues to memorialize Dr. Goldstein: the Michigan Biology of Cardiovascular Aging Leadership Development Fund at the Frankel Cardiovascular Center (https://giving.umich.edu/give/393178) and the Adenoid Cystic Carcinoma Foundation (https://accrf.org).
The JHLT has also re-published Dr. Goldstein’s farewell message in the September 2024 issue of the Journal. You can read it here: https://www.jhltonline.org/article/S1053-2498(24)01741-8/fulltext
Follow along at www.jhltonline.org/current, or, if you’re an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
In this special episode of JHLT: The Podcast, the Digital Media Editors connect with Joseph Rogers, MD, the new Editor-in-Chief of JHLT.
In the conversation, Dr. Rogers shares more about his vision for the Journal, how he plans to tackle the challenges and opportunities facing the publication, and a little about his life both inside and outside of medicine.
In addition to being the new Editor-in-Chief, Dr. Rogers is the President and CEO of the Texas Heart Institute in Houston, a past president of the ISHLT, and a prolific contributor to the field of heart and lung transplantation.
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On the second August episode of JHLT: The Podcast, the Digital Media Editors discuss a paper from the August issue of JHLT, entitled “A modular simulation framework for organ allocation.”The episode is hosted by Digital Media Editor Erika Lease, MD, FCCP, a transplant pulmonologist from the University of Washington.
The guests for this episode are first author Johnie Rose, MD, PhD, of the Center for Community Health Integration at Case Western Reserve University School of Medicine, and lead author Maryam Valapour, MD, MPP, of the Department of Pulmonary Medicine at the Cleveland Clinic.
In the episode, Drs. Rose and Valapour share the findings from their study, and tackle questions about the limitations of simulation models, what makes their COMET model different from past Simulation Allocation Models (SAMs), and why they made the project open-source.
Follow along at www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don’t already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.
-
On this episode of JHLT: The Podcast, the JHLT Digital Media Editors discuss a brand new consensus document from the ISHLT entitled “Strategies to Prevent Hemocompatibility Related Adverse Events in Patients with a Durable, Continuous-Flow Ventricular Assist Device.” The episode is hosted by Digital Media Editor Erika Lease, MD, FCCP, a transplant pulmonologist from the University of Washington.
The consensus document’s lead author, Ian Hollis, PharmD, a heart failure pharmacist and Associate Professor from the University of North Carolina in Chapel Hill, joins the podcast to discuss the document. During the discussion, he’s reunited with co-author and JHLT Podcast co-host Van-Khue Ton, MD, for a lively discussion of the document’s findings and takeaways.
If you work with heart failure patients with durable VADs, you’ll want to listen to this episode—and check out the complete document at ISHLT.
Stay tuned for a second episode later this month, where we’ll be talking about a modular simulation framework for organ allocation.
- Visa fler
