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irritable.ir·ri·ta·ble/ˈirədəb(ə)l/adjective"having or showing a tendency to be easily annoyed or made angry."irritable. is a show about the things that make one man angry. From CBD oil to farmers markets to automatic tipping, host Jesse takes you on a tour of the world seen through his eyes... his irritable, judgmental eyes. Listen now wherever you enjoy podcasts.