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In this episode, my guest is Bill Eddy, a lawyer, licensed therapist, professional mediator, and faculty member at the Pepperdine University School of Law. He specializes in identifying, reducing friction with, and disentangling from high-conflict individuals. We explain how high-conflict personalities differ from personality disorders and examine the cycles of blame and drama that cause persistent conflict in their relationships.We discuss how to quickly recognize high-conflict individuals based on specific criteria and behaviors, helping listeners learn to spot their less obvious tactics. You’ll also learn how to disengage from them with minimal friction and understand the methods they use to draw people back in or keep conflict alive.Additionally, we cover effective communication strategies for mediating situations involving high-conflict individuals, emphasizing empathy and problem-solving approaches. This episode equips listeners with tools to navigate conflict in various contexts, promoting resolutions that benefit all parties involved.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanMaui Nui Venison: https://mauinuivenison.com/huberman ExpressVPN: https://expressvpn.com/huberman Function: https://functionhealth.com/huberman David Protein: https://davidprotein.com/huberman Timestamps00:00:00 Bill Eddy00:02:58 Sponsors: Maui Nui & ExpressVPN00:06:41 High-Conflict Families, High-Conflict Individuals & Patterns00:10:48 Personality Disorders, Prevalence & Overlap00:18:28 High-Conflict Personality vs. Personality Disorders, Blame00:24:33 High-Conflict Individuals, Tool: First-Year Rule & Commitment00:30:53 Sponsor: AG100:32:05 Relationship Stability, Tool: Vetting Potential Partners00:38:54 Heightened Emotions, Negative Advocates, Divorce00:47:50 Brain, Plasticity & Fear; Bullies, Polarization00:54:51 Sponsors: Function & David00:58:00 Emotions, Media, Politics01:04:57 Tool: WEB Method, Identify High-Conflict Individuals01:12:20 Body Cues, Identify High-Conflict Individuals01:18:40 Tool: Don’t Label & Empathy; Adapting Your Behavior01:23:12 High Conflict Personalities & Occupations01:28:18 Big Personalities: Evidence vs Assumptions01:37:27 Tool: Leaving a Combative High-Conflict Individual, Blame, Gradual Exit 01:45:41 Exiting a High Conflict Relationship & Timing01:49:27 Tool: Disentangling from a Victim High-Conflict Individual, “Hoovering” 01:52:32 High Conflict Divorce, Small Families & Parental Estrangement 01:57:01 Tool: Managing Emotions & Relationships, EAR Statements01:59:52 Large Families & Conflict Resolution02:04:11 Bullies & Online Social Groups 02:09:18 Personality Disorders, Causes, Culture02:13:09 Tool: 4 “Fuhgeddaboudits”, Topics to Avoid in High Conflict Resolution02:19:50 Tool: CARS Method, Connecting & EAR Statements, Analyzing02:27:03 Tool: CARS Method, Responding & BIFF Response, Setting Limits & SLIC02:36:40 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, I explain what microplastics are, their prevalence in the human body and environment, and their common sources, as well as their potential negative health impacts. I provide practical strategies for limiting exposure to microplastics, nanoplastics, and endocrine disruptors such as bisphenol-A (BPA), bisphenol-S (BPS), phthalates, and PFAS ("forever chemicals"). Additionally, I discuss methods to enhance the body's detoxification and excretion of microplastics.By the end of this episode, you will have a clear understanding of the modern science of microplastics and their impact on human biology, along with actionable steps to minimize exposure and accumulation in the brain and body.Access the full show notes for this episode at hubermanlab.com.Use Ask Huberman Lab, our chat-based tool, for summaries, clips, and insights from this episode: https://go.hubermanlab.com/zqHpOM6Thank you to our sponsorsAG1: https://drinkag1.com/hubermanLMNT: https://drinklmnt.com/hubermanBetterHelp: https://betterhelp.com/hubermanFunction: https://functionhealth.com/hubermanEight Sleep: https://eightsleep.com/huberman Timestamps00:00:00 Microplastics00:02:46 Sponsors: LMNT & BetterHelp00:05:40 Microplastics & Nanoplastics; Ingestion00:09:38 Microplastics in Human Tissues; Pregnancy, Young Kids, BPA00:19:21 Tools: Plastic Water Bottles; Water Filters; Alternative Water Bottles00:26:57 Tool: Sea Salt00:29:10 Sponsor: AG100:30:40 Tool: Canned Soup; BPA, BPS, Phthalates00:34:55 Tools: Plastic Containers & Microwave; Paper Cups & Hot Liquids00:37:34 Measurement Tools & Advancements00:41:29 Nanoparticles & Tissues; Irritable Bowel Syndrome (IBS)00:45:27 Testosterone, Phthalates, BPA & BPS; Women; Men & Sperm Health00:52:17 Sponsors: Function & Eight Sleep00:55:25 Polyethylene & Plaques; PFAS “Forever Chemicals”; Microplastic Excretion01:00:02 Liver-Controlled Detoxification; Tool: Cruciferous Vegetables, Sulforaphane01:08:32 Tools: Fiber Intake, Non-Stick Pans, Carbonated Water; Microplastics & Cancer01:15:05 Tool: Sweating & Toxin Removal01:18:21 Tools: Packaged Foods; Clothing Overconsumption & Laundry01:25:11 Tools: Microwave Popcorn, Toothpastes01:27:47 Developing Brain & Microplastics, ADHD, Autism01:32:19 Tool: Receipts & BPAs; Minimizing Microplastic Exposure01:34:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Ari Wallach, most recently an adjunct associate professor at Columbia University's School of International and Public Affairs and host of a new TV series titled A Brief History of the Future. We discuss the importance of learning to project our understanding of ourselves and our goals into the future, both for our own sake and for future generations. We also explore how this fosters a sense of unity and community within our species.We examine how technology and modern society influence our perception of time and our ability to make decisions in a fast-paced, reward-driven environment that leads to our best possible future. Additionally, we discuss how the dismantling of traditional institutions has altered people's sense of purpose. We outline protocols to cultivate long-term thinking, connect with core values, and define a deep sense of purpose. This episode provides listeners with actionable tools to merge short- and long-term thinking in ways that create a positive, lasting impact on ourselves, society, and the planet.Access the full show notes for this episide at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanDavid Protein: https://davidprotein.com/hubermanHelix Sleep: https://helixsleep.com/hubermanROKA: https://roka.com/hubermanLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Ari Wallach00:01:58 Sponsors: David, Helix Sleep & ROKA00:06:13 Mental Time Travel; Technology & Present00:15:46 Technology; Tools: Transgenerational Empathy; Bettering Today00:22:00 Tool: Empathy for Others00:26:09 Empathy for Future Generations, Emotion & Logic00:31:48 Tool: Emotion to Guide Action00:36:50 Sponsor: AG100:38:02 Tools: Perfect Day Exercise; Cathedral Thinking, Awe & Future Generations00:43:52 Egoic Legacy, Modeling Behavior00:51:13 Social Media, Time Capsule, Storytelling01:00:06 Sponsor: LMNT01:01:18 Short-Term Thinking; Life Purpose, Science & Religion01:09:23 Longpath, Telos, Time Perception01:15:19 Tools: Photo Frames; Behavior & Legacy; Life in Weeks01:23:02 Tool: Visualizing Future You01:30:17 Death, Western Society01:36:20 Tool: Writing Letter to Future Self01:41:01 Society, Future Harmony01:47:03 Traditional Institutions, Family, Future Consciousness; “Protopia”01:58:48 Tool: Behavior & Modeling for the Future02:08:11 Tool: “Why Tuesdays?”, Examining Self02:14:58 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
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In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance.We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins.Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanJoovv: https://joovv.com/hubermanBetterHelp: https://betterhelp.com/hubermanFunction: https://functionhealth.com/hubermanEight Sleep: https://eightsleep.com/hubermanTimestamps00:00:00 Dr. Craig Koniver00:04:52 Sponsors: Joovv & BetterHelp00:07:40 What is a Peptide?00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation00:18:43 BPC-157, Inflammation00:23:27 BPC-157, Injection & Oral Forms; Injury Repair00:28:43 Sourcing, Anabolic Steroids, Testosterone00:34:48 Black & Gray Market, Compounding Pharmacies, Purity00:38:20 Sponsor: AG100:39:51 Partnering with a Physician, LPS00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides00:58:45 Sponsor: Function & Eight Sleep01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health01:05:16 Prescriptions, Physicians & Trust01:14:09 Agency in Your Health01:17:13 MK-677, Appetite01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing01:21:10 Methylated B Vitamins, Homocysteine01:24:47 Peptides for Sleep, Pinealon, Epitalon01:31:03 Glycine, Liver Detoxification; Dosage01:37:19 GLP-1, Compounding Pharmacies01:39:03 Stem Cell Therapy, PRP01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses01:50:20 Covid, NAD Infusion, NMN & NR Supplements01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR02:07:53 PT-141, Vyleesi, Libido; Nausea02:10:57 FDA Approval & Removal, Pharmaceutical Companies02:20:17 Positivity, Mindset & Health02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Charan Ranganath, Ph.D., professor of psychology and neuroscience at the University of California, Davis, and a world expert on the neuroscience of memory. We discuss how memory works, what causes diseases of dementia like Alzheimer’s, and science-based strategies to reduce age-related cognitive decline. We also cover the essential role of curiosity and the dopamine-curiosity link that can assist memory formation and neuroplasticity.We then discuss challenges with attention and focus, and how to overcome them, as well as how to manage task-switching and create home and work environments more conducive to cognitive health and longevity. Additionally, we explore the emotional aspect of memories, tools for overcoming rumination, and strategies for reframing past negative experiences.This episode will be of interest to anyone seeking to improve and maintain their cognitive health, focus, and memory across their lifespan, as well as for those struggling with ADHD.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanDavid Protein: https://davidprotein.com/hubermanLevels: https://levels.link/hubermanWaking Up: https://wakingup.com/hubermanFunction: https://functionhealth.com/hubermanTimestamps00:00:00 Dr. Charan Ranganath00:02:06 Sponsors: David, Levels & Waking Up00:06:48 Memory: Past, Present & Future; Sleep00:13:23 Self, Memory & Age, Neuroplasticity00:18:50 Tool: Curiosity & Dopamine00:26:55 Dopamine, Forward Movement00:33:09 Sponsor: AG100:34:22 Dopamine, Learning; Curiosity & Appraisal00:40:31 Memory, Hippocampus00:43:34 Prefrontal Cortex & Memory, Aging00:50:07 Aging, Prefrontal Cortex & Memory; Depression, Rumination00:58:53 Sponsor: Function01:00:40 Tool: Lifestyle Factors, Minimizing Age-Related Cognitive Decline01:09:39 Exercise, Brain Function; ADHD01:17:26 Sense of Purpose, Tool: Values, Goals, Navigating ADHD01:23:31 Forgetting, Intention vs. Attention01:30:10 Tool: Smartphones, Task-Switching, Forgetfulness01:36:36 Tool: Pictures, Memories, Intention01:45:46 Deep Focus, Dopamine01:49:36 Hearing, Vision, Oral Hygiene, Inflammation, Brain Health, Alzheimer’s01:59:51 Déjà Vu02:09:00 Serotonin, Reframing Memories, Trauma02:19:05 Psychedelics, Neuroplasticity, Perspective, Group Therapy02:27:53 Rumination, Trauma, Nostalgia, Narrative02:30:30 Music, Pavlov’s Dogz Band02:36:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Victor Carrión, M.D., the Vice-Chair of Psychiatry and Behavioral Sciences at Stanford School of Medicine and a world expert on the understanding and treatment of post-traumatic stress disorder (PTSD) in children, adolescents, and adults.We explain why, as children, we are particularly vulnerable to PTSD and how stress and trauma affect the developing brain. We also discuss how PTSD is related to attention-deficient hyperactivity disorder (ADHD) and vice versa.Dr. Carrión shares effective therapeutic interventions for PTSD, including cue-centered therapy (CCT) and how to create a custom “toolbox” to help you identify triggers and manage stress. We discuss an emerging curriculum that combines yoga and mindfulness to help people with PTSD improve their stress resilience, mood, and sleep.The episode will provide listeners of all ages with a clear understanding of PTSD and effective strategies to heal from it.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanEight Sleep: https://eightsleep.com/huberman BetterHelp: https://betterhelp.com/hubermanWaking Up: https://wakingup.com/hubermanFunction: https://functionhealth.com/hubermanTimestamps00:00:00 Dr. Victor Carrión00:01:56 Sponsors: Eight Sleep, BetterHelp & Waking Up00:06:19 Stress, Post-Traumatic Stress Disorder (PTSD), Avoidance00:11:41 Stressors, Perseverate; Children & PTSD00:16:13 Transgenerational Trauma00:19:20 Post-Traumatic Stress Injury (PTSI); Children, Dissociation & Cortisol00:27:17 Cortisol & Brain, Post-Traumatic Stress Symptoms00:31:48 Sponsor: AG100:33:19 PTSD, Attention Deficit Hyperactivity Disorder (ADHD)00:40:17 PTSD & ADHD; Identifying Cues, Triggers & Interventions00:47:49 PTSI, Autonomic Nervous System Seesaw; Sleep00:53:11 PTSD, Brain Development & Kids; Cue-Centered Therapy01:02:37 Sponsor: Function01:04:25 Limbic Pathway, Inner Dialogue, Therapy Toolbox01:12:34 Agency & Control, Deliberate Cold Exposure, Narrative01:18:11 Custom Toolbox Development; Energy01:26:32 Tool: 4-Corner Square Response, Understanding Cues01:32:59 Tool: “Creating Space,” Feelings Thermometer, Analyzing 4-Corners01:38:47 Social Media, Boundaries01:46:07 School, Yoga & Mindfulness Curriculum01:55:31 Implementing School Mindfulness Programs, Sleep02:00:52 Barriers to School Programs02:06:08 Redefining Success, Identity02:10:33 Resilience & Adaptation; Organoids, Epigenetic Treatment Response02:21:42 Listening to Kids & Adults02:24:19 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Esther Perel, a world-renowned psychotherapist, relationship expert, and bestselling author. She explains healthy romantic relationship dynamics and how to achieve them. The answer includes curiosity not just about the other person but, more importantly, about who we can evolve into through healthy relating.Esther explains the fundamental differences and challenges in relationships formed at different stages of life. We also discuss relationship conflict and how to give and receive a true apology.Additionally, we discuss fidelity, breaches of trust, reviving relationships, and tools for understanding your needs regarding love and desire in a relationship. The episode will help listeners understand the key elements to find, build, and revive deeply satisfying romantic relationships.Access the full show notes for this episode at hubermanlab.com.Esther Perel's new Desire courses are launching tomorrow, September 17—use code HUBERMAN15 for 15% off any course through December.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanDavid Protein: https://davidprotein.com/hubermanLMNT: https://drinklmnt.com/hubermanHelix Sleep: https://helixsleep.com/hubermanFunction: https://functionhealth.com/hubermanTimestamps00:00:00 Esther Perel00:02:03 Sponsors: David Protein, LMNT & Helix Sleep00:06:33 Romantic Relationships, Change & Self00:11:18 Cornerstone vs. Capstone Relationships, Age Differences00:16:53 Young vs. Older Couples, Dynamic Relationships00:20:13 Identity & Relationship Evolution00:26:00 Curiosity, Reactivity00:30:29 Sponsor: AG100:31:59 Polarization, Conflict; Coherence & Narratives00:38:21 Apologies, Forgiveness, Shame, Self-Esteem00:45:00 Relationship Conflict00:53:48 Sponsor: Function00:55:35 Verb States of Conflict; Emotion, Narratives vs. Reality01:00:10 Time Domains & Hurt; Caretaker & Romantic Relationships01:08:03 Couples Therapy; Language & Naming01:20:15 Sexuality in Relationships01:26:20 Tool: Love & Desire, Sexuality01:31:28 Infidelity, “Aliveness”01:35:17 Intimacy, Abandonment, Self-Preservation01:41:26 Erotic Blueprints, Emotional Needs01:49:42 Tool: Repair Work, Relationship Revival; Sincere Apologies01:59:30 Tool: Relationship Readiness02:03:33 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Marc Brackett, Ph.D., a professor in the Child Study Center at Yale University, director of the Yale Center for Emotional Intelligence, and a world expert on what emotions are, how to interpret them, and how to work with emotions to yield a more impactful, meaningful and healthier life. We explore differences between introverts and extroverts, in-person and text-based emotional communication, and how emotional suppression impacts us.We discuss emotional intelligence and describe tools to improve emotional regulation and communication in personal and professional relationships. We also explore the role of emotions in learning, resolving conflicts, and decision-making. We also discuss bullying in kids and adults, both in person and online. This episode provides a clear and novel framework for thinking about emotions and data-supported tools to improve emotion regulation, self-awareness, and empathic attunement.Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com.Pre-Order Andrew's New BookProtocols: An Operating Manual for the Human Body: https://protocolsbook.comThank you to our sponsorsAG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/hubermanEight Sleep: https://eightsleep.com/hubermanEudēmonia: https://eudemonia.netLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Dr. Marc Brackett00:02:02 Sponsors: BetterHelp, Eight Sleep & Eudēmonia00:06:03 What is Emotional Intelligence?; Self & Others00:11:18 Language & Emotion00:18:52 Emojis; Anger vs. Disappointment; Behavior & Emotion00:24:35 Sponsor: AG100:26:05 Parent/Teacher Support; Online Etiquette00:31:24 Anonymity, Online Comments00:35:46 Happiness vs. Contentment; Knowing Oneself00:41:33 Introversion & Extroversion; Personality & Emotional Intelligence00:51:28 Sponsor: LMNT00:52:40 Texting & Relationships01:00:37 Tool: Mood Meter, Energy & Pleasantness Scale01:06:28 Emotion Suppression; Permission to Feel, Emotions Mentor01:19:42 Discussing Feelings; Emotional Self-Awareness01:25:00 Understanding Cause of Emotions, Stress, Envy01:33:40 Framing Empathy, Compassionate Empathy01:42:28 Asking Question; Tools: Reframing, Hot Air Balloon; Distancing01:49:44 Stereotypes, “Emotional”01:53:49 Emotions, Learning & Decision Making; Intention02:02:43 Emotion App & Self-Awareness; Gratitude Practice02:07:13 Bullying02:18:06 Courage & Bullying; Emotion Education02:25:33 Punishment; Uncle Marvin02:31:59 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Jamil Zaki, Ph.D., professor of psychology at Stanford University, director of the Stanford Social Neuroscience Laboratory, and the author of the new book Hope for Cynics. We discuss cynicism and its healthier, more adaptive alternative, healthy skepticism, and how embracing healthy skepticism can enhance both our emotional and physical health.We discuss the data on how cynicism affects us as individuals and in relationships, causing lower levels of happiness, poorer physical health, and reduced creativity, trust, and collaboration. He also explains novel data-supported tools that we can use to shift ourselves towards a more informed yet more positive worldview and how to adopt a mindset of “hopeful skepticism” — the ideal stance to navigate life. Dr. Zaki offers listeners a positive, hopeful view of humanity grounded in cutting-edge research from his laboratory and other top laboratories. He also offers science-supported protocols to navigate relationships in person and online better. Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com.Pre-Order Andrew's New BookProtocols: An Operating Manual for the Human Body: https://protocolsbook.comThank you to our sponsorsAG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman Joovv: https://joovv.com/huberman Waking Up: https://wakingup.com/huberman Function: https://functionhealth.com/huberman Timestamps00:00:00 Dr. Jamil Zaki00:02:12 Sponsors: Maui Nui, Joovv & Waking Up00:06:59 Cynicism00:12:38 Children, Attachment Styles & Cynicism00:17:29 Cynicism vs. Skepticism, Complexity00:23:30 Culture Variability & Trust00:26:28 Sponsor: AG100:27:40 Negative Health Outcomes; Cynicism: Perception & Intelligence00:35:59 Stereotypes, Threats00:39:48 Cooperative Environments, Collaboration & Trust00:44:05 Competition, Conflict, Judgement00:48:46 Cynics, Awe, “Moral Beauty”00:55:26 Sponsor: Function00:57:13 Cynicism, Creativity & Workplace01:04:19 Assessing Cynicism; Assumptions & Opportunities01:11:11 Social Media & Cynicism, “Mean World Syndrome”01:18:35 Negativity Bias, Gossip 01:24:03 Social Media & Cynicism, Polarization, “Hopeful Skepticism” 01:32:59 AI, Bias Correction01:39:05 Tools: Mindset Skepticism; Reciprocity Mindset; Social Savoring01:46:05 Tools: Leaps of Faith; Forecasting; Encounter Counting01:51:33 Tool: Testing & Sharing Core Beliefs01:58:09 Polarization vs. Perceived Polarization, Politics02:06:06 Challenging Conversations, Questioning Perceptions 02:14:04 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, I discuss science-supported protocols to optimize your depth and rate of learning of material and skills. I explain the neurobiology of learning and neuroplasticity and how correctly timed, self-directed test-taking can be leveraged to improve learning and prevent forgetting. I discuss the study habits of the most successful learners, ways to limit distractions, how to set study goals, and how tests can be used as tools to learn, not just as a means for evaluating one’s mastery of learned material. A surprising aspect of tests, specifically self-testing soon after exposure to new material, is that they can significantly improve your ability to learn, apply, and maintain new knowledge. I also discuss tools to improve focus and alertness while studying.By the end of this episode, you will have learned various science-supported actionable tools you can use to better learn, remember, and apply new information.Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com.Andrew's New BookProtocols: An Operating Manual for the Human Body: https://protocolsbook.comThank you to our sponsorsAG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman BetterHelp: https://betterhelp.com/huberman Waking Up: https://wakingup.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps00:00:00 Improve Studying & Learning00:02:11 Sponsors: Eight Sleep, BetterHelp & Waking Up00:06:45 Offsetting Forgetting00:08:22 Learning & Neuroplasticity00:13:06 Periodic Testing00:16:09 Focus & Alertness, Sleep, Tool: Active Engagement00:21:37 Tool: Improve Focus, Mindfulness Meditation, Perception Exercise00:24:38 Sleep & Neuroplasticity, Tool: Non-Sleep Deep Rest (NSDR)00:28:29 Tools: Study Habits of Successful Students00:36:21 Sponsor: AG100:37:33 Studying & Aspiration Goals; Challenging Material00:42:54 Tool: Testing as a Learning Tool00:48:23 Self-Testing, Repeated Testing00:55:29 Testing Yourself & Knowledge Gaps01:01:11 Sponsor: LMNT01:02:23 New Material & Self-Test Timing01:07:21 Familiarity vs Mastery01:10:55 Self-Testing & Offsetting Forgetting01:15:53 Best Type of Self-Tests; Phone & Post-Learning Distractions01:22:03 Tool: Gap Effects; Testing as Studying vs. Evaluation01:25:40 Tool: Emotion & Learning, PTSD, Deliberate Cold Exposure, Caffeine01:33:28 Tool: Interleaving Information; Unskilled, Mastery & Virtuosity01:39:10 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer
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In this episode, my guest is Dr. Teo Soleymani, M.D., a double-board-certified dermatologist and specialist in skin cancer and reconstructive surgery. We discuss science and clinically supported protocols to improve skin health and give your skin a more youthful appearance and structure, reducing premature aging and skin cancer risk.We discuss the impact of sun exposure on skin appearance and aging and the surprising relationship between sun exposure and skin cancer. We explain how mineral-based (inorganic) sunscreens differ from chemical (organic) sunscreens, whether sunscreen can minimize premature skin aging, reduce cancer risk, and if there are any health risks associated with sunscreen use.We discuss skincare routines to significantly improve skin appearance and how to select skincare products. We discuss how caffeine, nicotine, alcohol, and stress impact the skin and describe how nutrition and anti-inflammatory diets can improve skin health. We also discuss the causes and treatments for common skin conditions, including dandruff, acne, rosacea, eczema, psoriasis, and vitiligo.Our conversation also covers topics such as the use of retinoids, laser treatments, red-light phototherapy, supplements, and how to best monitor for skin cancer. This episode provides numerous actionable protocols, most of which are zero-to-low cost, for improving skin health and appearance, reducing cancer risk, and treating skin problems.Access the full show notes for this episode at hubermanlab.com.Pre-order Andrew's new book, Protocols, at protocolsbook.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanROKA: https://roka.com/hubermanJoovv: https://joovv.com/hubermanHelix Sleep: https://helixsleep.com/hubermanLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Dr. Teo Soleymani00:01:35 Sponsors: ROKA, Joovv & Helix Sleep00:05:45 Skin Turnover; Skin Appearance & Stress 00:13:35 Caffeine, Vasoconstriction & Skin Redness00:16:31 Nicotine, Vaping & Skin Appearance00:18:37 Alcohol, Skin Health00:24:33 Hydration, Fluid Intake & Genetics00:26:19 Tool: Selecting a Moisturizer00:29:28 Sponsor: AG100:30:40 Puffiness Under Eyes & Cause00:32:14 Tool: Skin Cleansing; Frequency, Showers00:41:57 Dry & Flaky Scalp, Dandruff00:46:09 Cost & Skincare Products00:50:20 Tool: Sun Exposure & Skin Health, Mood00:56:24 Sponsor: LMNT00:57:35 Sunscreens vs. Sunblocks; Mineral-Based (Inorganic) vs. Chemical (Organic) Sunscreen01:02:45 Physical Barriers, Sunscreens, Oral Supplements & Skin Cancer01:07:27 Skin Cancer, Genetics; Sunscreen, Premature Aging01:12:11 Premature Aging & Skincare00:15:56 Choose Mineral or Chemical Sunscreen?01:20:24 Polypodium Supplement, Sun Exposure, Skin Redness01:26:02 Tool: Selecting Mineral-Based Sunscreens01:28:30 Chemical Sunscreens & Blood-Brain Barrier01:30:13 Nutrition, Gut Microbiome & Skin Health01:34:28 Tool: Nutrition for Skin Health, Protein, Anti-Inflammatory; Collagen; Omega-301:42:58 Retinoids vs. Retinol, Skin Appearance01:49:45 Laser Resurfacing; Exfoliation, Microdermabrasion01:56:52 Red Light Therapy & Phototherapy, Face Masks, Light Panels02:04:10 Psoriasis, Phototherapy02:10:03 Vitiligo, Immune System & Skin Cancer Risk02:15:41 Acne, High Glycemic Index Foods, Dairy02:19:38 Rosacea, Types & Treatments02:23:00 Eczema, Immune System02:25:37 Popping Pimples & Acne Scars; Corticosteroids02:30:15 Tattoos; Tool: Monitoring for Skin Cancer, Moles, Annual Exams02:36:28 HPV, Cancer & Warts; Vaccine & Cancer Risk02:43:31 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity.We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health.We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others.Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanMateina: https://drinkmateina.com/hubermanEight Sleep: https://www.eightsleep.com/hubermanMaui Nui: https://mauinuivenison.com/hubermanLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Dr. Layne Norton00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui00:06:39 Science-Based Evidence, Mechanism vs. Outcome00:14:31 Meta-analysis, Methods, Evidence Quality00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data00:33:53 Sponsor: AG100:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis00:42:01 Protein Synthesis, Refractory Response; Resistance Training 00:46:05 Protein Intake, Intermittent Fasting & Training00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth01:05:34 Sponsor: LMNT01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet01:19:50 “The Norton Method”; Tool: Consistency01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest01:33:50 Mind & Body Effects, Stress; Belief Effects01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training01:50:24 Fatigue & Training to Failure, Speed, Strength Training01:59:06 Tool: Training After 50, Consistency02:09:12 Fat Cells, Diabetes, Exercise02:16:50 Metabolism & Age-Related Changes?, Appetite02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise”02:33:42 GLP-1 Agonists, Judgement & Obesity02:40:19 Sugar, Excess Calories, Body Weight02:49:16 Satiety, Sugar & Calorie Budget02:54:56 Tool: Individualization, Context & Diet Psychology02:57:22 Seed Oils, Butter, Olive Oil03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits03:13:43 Saturated Fat, Cholesterol; Seed Oils03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein03:57:00 Evidence-Based Approach04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development. Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships.We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences. By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life. Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanBetterHelp: https://betterhelp.com/hubermanHelix Sleep: https://helixsleep.com/hubermanLMNT: https://drinklmnt.com/hubermanWaking Up: https://wakingup.com/hubermanTimestamps00:00:00 Dr. Martha Beck00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT00:05:34 Tool: Perfect Day Exercise00:15:31 “Clear Eyed”, Male vs. Female00:23:31 Family & Work; Directed Attention & Miracles00:30:21 Sponsor: AG100:32:10 Unease, Restlessness & Guilt; Life Worth, Fear00:37:22 Accessing the Subconscious; Compassionate Witness Self00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting00:54:01 Self, Radiance, Death; Awakening00:59:14 Suffering & Compassionate Attention01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind;01:08:44 Sponsor: Waking Up01:10:20 Western Society & Pressure01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World”01:25:02 Energy, Magnetoreception, Pet’s Death01:33:49 Lying to Ourselves, Addiction01:38:18 Tool: “Integrity Cleanse”, Lies; The Light01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency01:55:10 Romantic Relationships; Jobs & Family02:02:06 Hurting Others, Relationship Imbalance02:06:55 Tool: True Empathy02:11:26 “Happiness is an Inside Job”, Codependency02:18:58 Live Your Joy, Western Society02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird”02:30:42 “I Like It!”, Punk Rock Music, Love02:34:24 Honesty & Essential Self; Helping People & Healers02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium.
Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors.
If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023.
If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here.
Timestamps
00:00 Introduction & Announcements
00:15 Supporting Mental & Physical Health Research
01:56 Exciting New Research Initiatives
03:39 Skin Health & Appearance
14:46 Cold Therapy Benefits & Guidelines
21:18 Self-Motivation Strategies
27:05 Understanding REM Sleep
28:45 Morning Routine: Exercise & Cold Exposure
29:17 The Importance of REM Sleep
29:49 Non-Sleep Deep Rest (NSDR) Protocols
31:27 REM Sleep Rebound & Compensation
32:55 Impactful School Strategies for Learning
34:19 Meditation & Micro Gaps in Learning
39:13 Physical Activity & Learning
41:01 Exploring Shilajit & Testosterone
47:51 Writing Process & Overcoming Obstacles
51:32 Addiction & Recovery Resources
53:47 Closing Remarks & Gratitude
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In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive. We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan. Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk. Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps00:00:00 Dr. Peter Attia, NAD Pathway00:02:31 Sponsors: LMNT, Levels & Eight Sleep00:06:38 Categories of Longevity Approaches00:17:22 Peter’s Supplements; Rapamycin & Research Data00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho00:30:35 Sponsor: AG100:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol00:53:31 Perform with Dr. Andy Galpin Podcast00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits01:30:38 Longevity, NR & NMN Supplementation, Inflammation01:41:00 Rapamycin & Immune Function01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor 01:55:24 Radiation & Cancer Risk01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline02:07:12 Tool: Exercise Timing & Energy Levels02:11:22 Peter’s Supplements02:18:46 Andrew’s Supplements02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy 02:26:52 NAD Pathway Supplementation for Longevity?02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network NewsletterDisclaimer
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In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals.We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity. We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health.Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanMaui Nui Venison: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman Timestamps00:00:00 Dr. Stacy Sims00:02:24 Sponsors: Maui Nui, Eight Sleep & Waking Up00:07:03 Intermittent Fasting, Exercise & Women00:12:50 Cortisol & Circadian Rhythm, Caffeine & Training00:17:25 Reps in Reserve, Rate of Perceived Exertion (RPE); Age & Women00:21:06 Pre-Training Meal & Brain, Kisspeptin00:26:45 Post-Training Meal & Recovery Window00:29:59 Sponsor: AG100:31:48 Hormones, Calories & Women00:34:24 Women, Strength Improvements & Resistance Training00:39:10 Tool: Women & Training Goals by Age Range00:44:16 Women, Perimenopause, Training & Longevity00:47:14 Women & Training for Longevity, Cardio, Zone 200:51:42 Tools: How to Start Resistance Training, Machines; Polarized Training00:58:23 Perform with Dr. Andy Galpin Podcast00:59:10 Menstrual Cycle & Training, Tool: Tracking & Individual Variability01:04:31 Tool: 10-Minute Rule; High-Intensity Training & Menstrual Cycle01:08:36 “Train Hard & Eat Well”; Appetite, Nutrition & Menstrual Cycle01:12:22 Oral Contraception, Hormones, Athletic Performance; IUD01:20:57 Evaluating Menstrual Blood, PCOS; Hormones & Female Athletes01:26:31 Iron, Fatigue; Blood Testing & Menstrual Cycle01:29:33 Caffeine & Perimenopause; Nicotine, Schisandra01:34:24 Deliberate Cold Exposure & Women, Endometriosis; Tool: Sauna & Hot Flashes01:42:19 Tools: “Sims’ Protocol”: Post-Training Sauna & Performance; “Track Stack”01:49:37 Women, Hormones & Sleep, Perimenopause & Sleep Hygiene01:52:54 Supplements: Creatine, Water Weight, Hair Loss; Vitamin D301:57:21 Protein Powder; Adaptogens & Timing02:00:11 Pregnancy & Training; Cold & Hot Exposure02:06:19 Tool: Women in 50s & Older, Training & Nutrition for Longevity02:09:38 Tool: Women in 20s-40s & Training, Lactate02:12:18 Tool: What is High-Intensity Training?, Cardiovascular Sets & Recovery02:17:22 Training for Longevity, Cellular & Metabolic Changes02:19:30 Nutrition, 80/20 Rule02:23:30 Listening to Self02:26:00 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
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In this episode, my guest is Dr. Stuart McGill, Ph.D., a distinguished professor emeritus of spine biomechanics at the University of Waterloo and a world expert on spine anatomy and physiology, back pain, and rehabilitation. We discuss the most common sources of back pain, how back pain can be assessed (including self-assessment techniques), and how to design a personalized recovery plan to reduce back pain.We discuss how to train for lifelong fitness, reduce injury risk, and protect your back and joints based on your age and personal goals. We also discuss how to prevent back pain, build core stability, and explain how “McGill’s Big 3” exercises protect and strengthen the back. Dr. McGill, who is exceptionally fit in his late 60s, describes his low-time investment, personal training routine, and the specific exercises he uses for mobility, strength, and cardiovascular fitness.We also discuss controversial issues in the back pain and rehabilitation field, including how pain originates, the biopsychosocial model of pain, and treatments such as platelet-rich plasma (PRP). This episode provides clear, actionable tools to strengthen, prevent, and remedy back pain and injury so you can be pain-free while enjoying sports, exercise, and daily activities at any age.Access the full show notes for this episode at hubermanlab.com.Watch the clip on back pain relief and spine anatomy that accompanies this episode.Demonstration of The McGill MethodThank you to our sponsorsAG1: https://drinkag1.com/hubermanHelix Sleep: https://helixsleep.com/hubermanBetterHelp: https://betterhelp.com/hubermanWaking Up: https://wakingup.com/hubermanLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Dr. Stuart McGill00:02:33 Sponsors: Helix Sleep, BetterHelp & Waking Up00:06:23 What Causes Back Pain?; Genetics, Dog Breed Analogy00:12:55 Tool: Skeleton & Body Type; Spine Flexibility & Discs00:20:25 Flexibility & Exercises; Discs & Collagen00:25:43 Sponsor: AG100:27:32 Stress & Tipping Point; Athletic Tradeoffs, Triathletes00:36:17 Back Pain, Goals & Training Program00:45:57 Spine Hygiene, Back Pain, Powerlifting00:53:33 Genetics & Running00:59:34 Sponsor: LMNT01:00:46 Rehabilitation & Reducing Volume; Injury01:07:42 Tool: Training for Lifelong Fitness, Injury & Joints01:17:40 Pain Types, Biopsychosocial Model of Pain01:26:15 Coaching, Explosivity & Endurance01:32:43 Virtual Surgery & Rest, Pain Recovery01:41:25 Tool: McGill’s Big 3; Building Back Strength & Stability01:46:39 Inversion Tables & Spine Deloading, Disc Bulge, Tool: Lumbar Support01:51:09 Tool: Daily Walking; Sitting01:55:33 Deadlift & Bone Density, Glute-Ham Raise02:06:20 Training & Age, Osteoporosis, Tool: Deadlift Alternatives02:16:47 Tools: Biblical Training Week; Spine Stability & McGill’s Big 3; Shrinking & Age02:24:16 Platelet-Rich Plasma (PRP); Disc Damage02:27:56 Tools: Biblical Training Week & Strength Exercises, Neck Strength02:35:24 Tools: Sword Play, Distal Limb Loading, Training for Symmetry02:42:38 Tools: Biblical Training Week, Mobility & Cardiovascular Exercises, Athletic Panel02:49:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures
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In this episode, my guest is Dr. Matthew Hill, Ph.D., a professor of cell biology and anatomy at the Hotchkiss Brain Institute at the University of Calgary and an expert on the biology of cannabis. We discuss how cannabis affects the brain to produce its psychoactive effects (feeling “high”), including altered time perception, focus, memory, appetite, and stress.We discuss how THC vs. cannabidiol (CBD) affects the brain, the effects of different routes of cannabis administration (e.g., smoking, vaping, edibles), high-potency THC, and whether cannabis is addictive. We discuss if there is a link between cannabis use and the development of psychosis, anxiety, bipolar depression, or schizophrenia. We discuss whether CBD has clinical benefits in regulating stress, promoting sleep, and treating certain diseases. We also discuss if there are real and consistent differences in the biological effects of different cannabis strains, if cannabis impacts hormones, and the uses of cannabis for the management of pain, stress, Post-traumatic stress disorder (PTSD), anxiety, and nausea.Listeners of this episode will get an up-to-date understanding of what is currently known about how cannabis affects the brain and body, including both its potential benefits and risks.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanEight Sleep: https://www.eightsleep.com/hubermanLMNT: https://drinklmnt.com/hubermanBetterHelp: https://betterhelp.com/hubermanInsideTracker: https://insidetracker.com/hubermanTimestamps00:00:00 Dr. Matthew Hill00:00:00 Sponsors: Eight Sleep, LMNT & BetterHelp00:07:16 Cannabis, THC, Cannabidiol (CBD), Terpenes00:12:08 Psychoactive Effects, Cannabis “High”; Time Perception00:16:55 Cannabis & Brain, CB1 Receptor, Endocannabinoids00:26:19 Endocannabinoids Types: Anandamide, 2-AG00:33:46 “Munchies”, Cannabis & Appetite00:42:17 Sponsor: AG100:44:06 THC & Anandamide, Pharmacology00:52:37 THC & CB1 Receptors, Intoxication & Appetite00:58:57 Cannabis & Focus, Memory01:04:09 Routes of Administration, Concentration, Cannabis Research01:15:12 Self-Regulation, Inhalation & THC, Tolerance; THC Concentrates01:22:25 Sponsor: InsideTracker01:23:36 Addiction & Cannabis, Cannabis Use Disorder01:31:30 Cannabis Legalization & Use, Edibles & ER Visits01:36:48 Oral Consumption, Edibles, Dosing & Time Course01:41:12 Drug Testing & Cannabis, Exercise01:46:04 Cannabis & Hormones, Gynecomastia, Sperm Quality01:54:37 Cannabis & Pregnancy; Selling Recreational Cannabis02:04:07 Vaping02:07:05 Psychosis, Anxiety & Cannabis02:17:17 Cannabis, Psychosis, Schizophrenia & Genetics02:30:45 Cannabis Use & Schizophrenia, Manic Bipolar, THC Potency, Nicotine02:40:37 Schizophrenia, Cannabis Legalization02:45:06 Cannabis Strains, Indica, Sativa, Subjective Effects & Expectancy Bias02:57:00 CBD, Pediatric Epilepsy, Adenosine03:07:22 Entourage Effect; Placebo Effect, CBD & Doses03:19:12 Cannabis Health Risks, Cardiovascular Risk, Schizophrenia 03:27:08 Cyclic Vomiting Syndrome & Hot Shower03:31:30 Cannabis Benefits: Pain, Stress, Anxiety, Post-Traumatic Stress Disorder (PTSD)03:40:18 Cannabis & Anxiety, Anandamide & Stress Response03:45:55 Scientific Discussion, Clarification & Advancement03:49:47 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer
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In this episode, I discuss skin health and appearance and why both are important indicators of the health status of your immune system, gut microbiome, and other organ systems. I explain why sunlight is essential for skin and hormone health and how excessive sunlight can accelerate skin aging and cause certain skin cancers. I discuss the different types of sunscreens (physical, chemical, and mineral-based) and potential health concerns of the chemicals found in some (but not all) sunscreens.I also discuss the importance of getting your skin (and not just moles) checked for pre-cancerous and cancer growths, the role of nutrition and lifestyle factors that improve skin health and appearance, and how to improve your skin by reducing local and systemic inflammation and supporting your microbiome. I explain what works to improve your skin's youthfulness and appearance, including reducing wrinkles, sagging, and pore size. I review the data on ingesting (or topically applied) collagen, vitamin C, niacinamide, hyaluronic acid, and retinol, and what is known about the use of peptides (e.g., BPC-157, copper peptides) and red and far-red light phototherapies for improving skin health and appearance.I also discuss the causes of acne, rosacea, and psoriasis and explain nutritional, skin care, and prescription-based approaches to treating these common skin conditions.This episode ought to help everyone better understand the biology of the skin and help them make the best possible decisions for their skin health, care, and appearance according to age, goals, and current skin conditions.Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com.Andrew's New BookProtocols: An Operating Manual for the Human Body: https://protocolsbook.comThank you to our sponsorsAG1: https://drinkag1.com/hubermanJoovv: https://joovv.com/hubermanBetterHelp: https://betterhelp.com/huberman ROKA: https://roka.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps00:00:00 Skin Health00:02:59 Sponsors: Joovv, BetterHelp & ROKA 00:07:18 Skin Biology, Skin Layers00:12:40 Sun Exposure, UV Light & Skin Cancers; Sunscreen00:19:51 Aging, Sun Exposure, Skin Cancers, Physical Barriers00:27:24 Sunburn & Skin Cancers00:30:09 Sponsor: AG100:31:58 Vitamin D, Sun Exposure & Sunscreen00:36:50 Organic (Chemical) Sunscreen & Inorganic (Mineral-Based) Sunscreen00:49:20 Skin Cancers, Moles, Laser Resurfacing00:53:59 Sponsor: LMNT00:55:34 Sun Exposure, Melanoma & Life Expectancy01:03:13 Tool: Youthful Skin, Collagen & Vitamin C01:12:55 Peptides, BPC-157, Copper01:20:58 Tool: Niacinamide (Nicotinamide), Youthful Skin, Dark Spots, Hyaluronic Acid01:26:25 Tool: Retinol (Retin-A, Tretinoin, Retinyl Esters), Youthful Skin01:33:07 Tool: Phototherapy, Youthful Skin, Treating Skin Conditions01:41:10 Tool: Nutrition for Skin Health, Anti-Inflammatory Diets01:47:54 Highly Processed Foods, Advanced Glycation End Products & Skin Health01:52:08 Tools: Reduce Inflammation: Gut Microbiome, Sleep, Alcohol, Smoking, Stress01:58:58 Acne, Hormones & Insulin; Tool: Low Glycemic Diet, Dairy02:07:26 Tools: Face Cleansing & Acne; Scarring & Popping Pimples02:13:29 Tool: Treating Rosacea, Alcohol, Skin Care, Nutrition02:18:31 Stubborn Rosacea, Over Cleansing, Pulsed Dye Laser02:21:04 Psoriasis Treatment, Immune System & Prescriptions02:25:24 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer
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In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems.She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex. She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon’s practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health.Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com.Andrew's New BookProtocols: An Operating Manual for the Human Body: https://protocolsbook.comThank you to our sponsorsAG1: https://drinkag1.com/hubermanMaui Nui Venison: https://mauinuivenison.com/huberman Levels: https://levels.link/huberman Helix Sleep: https://helixsleep.com/hubermanInsideTracker: https://insidetracker.com/huberman Timestamps00:00:00 Protocols Book; Dr. Gabrielle Lyon00:03:23 Sponsors: Maui Nui, Levels & Helix Sleep00:07:40 Skeletal Muscle & Longevity00:11:25 “Under-muscled”, Leucine & Muscle Health00:15:55 Muscle Health00:19:45 Tool: Carbohydrate Consumption & Activity, Glycogen00:25:14 Tools: Nutrition for Healthy Skeletal Muscle, First Meal00:31:57 Sponsor: AG100:33:46 Quality Protein, Animal & Plant-Based Proteins00:37:36 Dietary Protein Recommendations, Meal Threshold00:41:19 Muscle Health & Aging00:46:02 Supplements & Creatine; Dietary Protein00:50:07 Tool: Dietary Protein Recommendation; Gout & Cancer Risk00:52:43 Effects of Dietary Protein & Exercise on Body Composition01:03:06 Thermic Effects, Protein 01:05:02 Sponsor: InsideTracker01:06:14 Protein & Satiety, Insulin & Glucose01:12:04 Tool: Older Adults, Resistance Training & Dietary Protein01:17:48 Dietary Protein, mTOR & Cancer Risk01:21:36 Muscle Span & Aging, Sedentary Behaviors01:24:00 Mixed Meals, Protein Quality, Fiber01:29:21 Inactivity & Insulin Resistance, Inflammation01:38:43 Exercise & Myokines, Brain Health & BDNF01:44:11 Tool: Resistance Training Protocols, Hypertrophy, “High Ground”01:52:51 High Ground Exercises; Tendon Strength; Training Duration, Blue Zones01:58:19 Movement, Exercise & Older Adults02:04:25 Tool: Protein Timing & Resistance Training; VO2 Max, Aging, Blood Work02:11:13 Supplements: Creatine, Urolithin A, Whey Protein, Fish Oil, Collagen02:20:18 Fasting, Older Adults; Tool: Meal Timing02:25:18 Animal Proteins & Dairy; Organ Meats, Vegan; Magnesium, Zinc02:30:59 Medications & Muscle Health02:32:49 Obesity & GLP-1 Analogs, Ozempic, Mounjaro, Skeletal Muscle02:40:48 Benefits of Skeletal Muscle & Aging02:42:16 Tools: Nutrition & Resistance Training for Muscle Health02:45:44 Mindset Tools: Standards vs. Goals; Vulnerability Points02:52:00 Mindset Tools: Neutrality; Health & Worth03:01:14 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter, Protocols BookDisclaimer
- Visa fler