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  • When you think of creatine you probably think about muscles, the gym, getting jacked. However, there's a new study that's looking at something totally different: creatine and cancer risk. We're gonna dive into this, break down what they found, and talk about what it actually means. Turns out, it's not as straightforward as you might think.

    We cover the following topics:
    00:00 - Intro
    00:45 - Creatine Overview
    03:15 - Study Overview
    05:19 - Main Findings
    07:24 - Mechanism of How This May Be
    08:22 - Quartiles of Creatine Intake
    10:24 - Subgroup Analysis
    12:26 - Implications
    13:54 - Limitations
    16:26 - Making Sense Of It
    16:58 - Outro

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    REFERENCES:

    Jiang, J., Zhao, H., Chen, J., Du, J., Ni, W., Zheng, B., Wu, J., & Xiao, C. (2025). The association between dietary creatine intake and cancer in U.S. adults: Insights from NHANES 2007–2018. Frontiers in Nutrition, 11. https://doi.org/10.3389/fnut.2024.1460057  



    *Disclaimer*

    This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • In this episode of the Building Lifelong Athletes podcast we talk about a meta analysis that looked at what exercise was best for improving type two diabetes.

    We cover the following topics:
    00:00 - Introduction
    00:33 - Diabetes Overview
    01:47 - Study Overview
    02:18 - Understanding HbA1C
    04:08 - Exercise and A1C: General Findings
    04:36 - Marker 7
    05:55 - What Type Of Exercise Is Best?
    08:42 - Direct Comparisons
    09:50 - Exercise Dosage
    11:12 - Explaining METs
    12:46 - Is More Better?
    13:22 - Dose Specifics for Different Exercise
    15:45 - Is HIIT King?
    17:52 - Other Factors Affecting Findings
    18:41 - Limitations
    19:26 - Final Thoughts
    21:18 - Outro

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com


    REFERENCES:

    Liang, Z., Zhang, M., Wang, C., Hao, F., Yu, Y., Tian, S., & Yuan, Y. (2024). The Best Exercise Modality and Dose to Reduce Glycosylated Hemoglobin in Patients with Type 2 Diabetes: A Systematic Review with Pairwise, Network, and Dose–Response Meta-Analyses. Sports Medicine, 54(10), 2557–2570. https://doi.org/10.1007/s40279-024-02057-6  

    *Disclaimer*

    This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

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  • In this episode of the Building Lifelong Athletes podcast we talk about apoB and why it is probably a better test than our standard lipid panel.

    We cover the following topics
    00:00 - Intro
    00:40 - apoB Introduction
    01:50 - apoB Structure and function
    05:47 - apoB and atherosclerosis
    07:29 - The Atherogenic Lipoprotein Particle Paradigm
    11:14 - apoB Measurement in Practice
    13:02 - apoB Target Goals
    18:13 - apoB Treatment
    19:51 - Arguments against apoB
    23:22 - The Evidence Supporting apoB
    26:43 - Conclusions
    29:50 - Outro

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com


    REFERENCES:

    Behbodikhah, J., Ahmed, S., Elyasi, A., Kasselman, L. J., De Leon, J., Glass, A. D., & Reiss, A. B. (2021). Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target. Metabolites, 11(10), 690. https://doi.org/10.3390/metabo11100690 De Oliveira-Gomes, D., Joshi, P. H., Peterson, E. D., Rohatgi, A., Khera, A., & Navar, A. M. (2024). Apolipoprotein B: Bridging the Gap Between Evidence and Clinical Practice. Circulation, 150(1), 62–79. https://doi.org/10.1161/CIRCULATIONAHA.124.068885 Glavinovic, T., Thanassoulis, G., de Graaf, J., Couture, P., Hegele, R. A., & Sniderman, A. D. (2022). Physiological Bases for the Superiority of Apolipoprotein B Over Low‐Density Lipoprotein Cholesterol and Non–High‐Density Lipoprotein Cholesterol as a Marker of Cardiovascular Risk. Journal of the American Heart Association, 11(20), e025858. https://doi.org/10.1161/JAHA.122.025858 Li, C., Zhang, Y., Mei, L., Jin, A., Cai, X., Pan, Y., Jing, J., Wang, S., Meng, X., Li, S., Wang, M., Wei, T., Wang, Y., Chen, R., & Tian, Y. (2023). Discordantly high Apo B with LDL-C or non-HDL-C in relation to presence and burden of cerebral atherosclerotic plaques. Journal of Clinical Lipidology, 17(4), 519–528. https://doi.org/10.1016/j.jacl.2023.05.104 Sniderman, A. D., Thanassoulis, G., Glavinovic, T., Navar, A. M., Pencina, M., Catapano, A., & Ference, B. A. (2019). Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiology, 4(12), 1287. https://doi.org/10.1001/jamacardio.2019.3780 Soffer, D. E., Marston, N. A., Maki, K. C., Jacobson, T. A., Bittner, V. A., Peña, J. M., Thanassoulis, G., Martin, S. S., Kirkpatrick, C. F., Virani, S. S., Dixon, D. L., Ballantyne, C. M., & Remaley, A. T. (2024). Role of apolipoprotein B in the clinical management of cardiovascular risk in adults: An Expert Clinical Consensus from the National Lipid Association. Journal of Clinical Lipidology, 18(5), e647–e663. https://doi.org/10.1016/j.jacl.2024.08.013  

    *Disclaimer*

    This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • Obesity isn't just about numbers on a scale or your BMI. It's a hidden epidemic silently fueling a range of diseases that we see every day. From heart failure and diabetes to Alzheimer's and even cancer, excess weight is a key player in about 70% of chronic diseases. Today, we expose the shocking truth about how obesity is hijacking our health and just how wide reaching this problem really is.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    00:48 - Non-Communicable Diseases
    02:28 - The Cost of Obesity
    03:21 - Obesity Causes Disability and Early Death
    06:27 - Overnutrition
    08:30 - Obesity and Cardiovascular Disease
    13:28 - Obesity and Lung Disease
    14:43 - Obesity and Diabetes
    17:12 - Obesity and Gastrointestinal Diseases
    19:18 - Obesity and Neurologic Diseases
    21:21 - Obesity and Cancer
    22:55 - The Obesity Paradox
    25:04 - Final Thoughts
    28:05 - Outro


    REFERENCES:

    Hildebrand, S., & Pfeifer, A. (2025). The obesity pandemic and its impact on non-communicable disease burden. Pflügers Archiv - European Journal of Physiology. https://doi.org/10.1007/s00424-025-03066-8  

    *Disclaimer* This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • In this episode of the Building Lifelong Athletes podcast, we discuss the pathophysiology, clinical presentation, and management of ganglion cysts.  

    We cover the following topics:

    What are ganglion cysts?  What causes ganglion cysts?  How are ganglion cysts diagnosed?  How are ganglion cysts treated?    

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    00:42 - Pathophysiology
    03:27 - Clinical Presentation
    05:34 - Diagnosis
    06:44 - Management
    09:40 - Patient Considerations
    11:04 - Conclusion


    REFERENCES:

    Gude, W., & Morelli, V. (2008). Ganglion cysts of the wrist: Pathophysiology, clinical picture, and management. Current Reviews in Musculoskeletal Medicine, 1(3–4), 205. https://doi.org/10.1007/s12178-008-9033-4  

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • Peptides have become increasingly popular in recent years, with many people touting their benefits for healing and performance enhancement. One peptide that has gained a lot of attention is BPC-157. But what does the science actually say about this peptide?

    In this episode of the Building Lifelong Athletes podcast, we dive into the research on BPC-157 and explore the potential risks and benefits of this peptide. We also discuss the hype surrounding BPC-157 and whether it lives up to the claims.

    We cover the following topics:

    What are peptides?  What is BPC-157?  What are the purported benefits of BPC-157?  What are the risks of using BPC-157?  What are the alternatives to BPC-157?  

    If you are interested in learning more about BPC-157, then this episode is for you.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    00:58 - What Are Peptides?
    02:50 - What is BPC 157?
    04:32 - Why Are These So Hyped Up?
    08:04 - What Is The Human Research?
    15:08 - What Are The Risks of BPC 157?
    18:28 - What Are The Alternatives?
    19:34 - Summary
    23:35 - Outro

    REFERENCES:

    DeFoor, M. T., & Dekker, T. J. (2025). Injectable Therapeutic Peptides-An Adjunct to Regenerative Medicine and Sports Performance? Arthroscopy : The Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International  Arthroscopy Association, 41(2), 150–152. https://doi.org/10.1016/j.arthro.2024.09.005

    Gwyer, D., Wragg, N. M., & Wilson, S. L. (2019). Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research, 377(2), 153–159. https://doi.org/10.1007/s00441-019-03016-8

    Lee, E., & Padgett, B. (2021). Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. Alternative Therapies in Health and Medicine, 27(4), 8–13.

     

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • Big Pharma and Big Supplement: Are They Really That Different?   Uncover the shocking truths about the supplement industry and how it compares to Big Pharma.   Discover the dark side of supplements, from misleading marketing and pseudo-scientific claims to contamination and inconsistent dosing.   Finally, learn how to protect yourself and make informed decisions about supplements. 

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    01:10 - Big Pharma
    14:22 - Supplement Industry Background
    17:29 - Supplement Industry Dark Side
    23:45 - Finances
    25:13 - How To Find A Safe Supplement
    28:36 - Conclusion

    REFERENCES:

    Cohen, P. A., Avula, B., Katragunta, K., Travis, J. C., & Khan, I. (2023). Presence and Quantity of Botanical Ingredients With Purported Performance-Enhancing Properties in Sports Supplements. JAMA Network Open, 6(7), e2323879. https://doi.org/10.1001/jamanetworkopen.2023.23879  

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • Ben Patrick, better known as the @kneesovertoesguy has taken social media by storm. You’ve probably seen him doing some incredibly athletic feat that looks like it should be impossible to do, and all while making it look effortless. He has turned traditional rehabilitation on its head, helped thousands of people, and upset quite a few rehab professionals on the way. Today we are diving into what makes his programs so effective for lots of people, and stick around to the end as I’ll give you a practical checklist for what you need to look for when looking for a knee rehab program.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:

    00:00 - Intro
    00:40 - Kneesovertoes Claims
    02:14 - Why this program works for so many people
    02:57 - Patient buy in
    05:20 - Progressive Loading
    11:29 - Autoregulation
    15:13 - How To Pick A Program
    22:17 - Summary
    22:58 - Outro

    REFERENCES:

    https://www.youtube.com/c/thekneesovertoesguy

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • There is a mental health crisis in adolescents.. and it’s not getting better anytime soon unless we change something. Our kids are depressed and anxious and not performing their best in school… but what if there was a way to improve all of these things that doesn’t involve medications or therapy but rather exercise? In today’s podcast we will dive in to a recent study that looked at how exercise can affect all these things. And stick around to the end where I give the practical takeaways on what we can actually do to help our children succeed.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: www.jrennickemd.com

    CHAPTERS:

    00:00 - Intro
    00:39 - The Study
    04:27 - Why does motor fitness improve cognition?
    06:49 - Better fitness = Better mood?
    09:55 - The Screen Time Dilemma
    12:05 - Practical Takeaways
    15:36 - Outro

    REFERENCES:

    Haapala, E. A., Leppänen, M. H., Skog, H., Lubans, D. R., Viitasalo, A., Lintu, N., Jalanko, P., Määttä, S., & Lakka, T. A. (2024). Childhood Physical Fitness as a Predictor of Cognition and Mental Health in Adolescence: The PANIC Study. *Sports Medicine*. https://doi.org/10.1007/s40279-024-02107-z

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • Do you worry too much about your health? Could it be possible that your concern for your health is actually making you less healthy? Today we are going to discuss an interesting article about health anxiety and how it may be worse for you than previously thought.

    Sign up for my newsletter at www.jrennickemd.com

    Timestamps:
    00:00 - Start
    00:12 - Article Intro
    01:47 - Objective
    02:03 - Study Design
    03:24 - Outcomes
    05:43 - Results
    08:26 - Discussion
    12:44 - Strengths/Limitations
    14:09 - Real World Takeaways
    20:46 - Outro

    References:

    Mataix-Cols, D., Isomura, K., Sidorchuk, A., Rautio, D., Ivanov, V. Z., Rück, C., Österman, S., Lichtenstein, P., Larsson, H., Kuja-Halkola, R., Chang, Z., Brickell, I., Hedman-Lagerlöf, E., & Fernández de la Cruz, L. (2024). All-Cause and Cause-Specific Mortality Among Individuals With Hypochondriasis. JAMA Psychiatry, 81(3), 284–291. https://doi.org/10.1001/jamapsychiatry.2023.4744  

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

     

    Music from #Uppbeat (free for Creators!): https://uppbeat.io/t/prigida/sapphire License code: AUHWDOXKRX2HM2FJ

  • Could Olive oil, a staple of the heart-healthy Mediterranean diet, actually be making your cholesterol worse? In this video, we dive into the "Recipe for Heart Health" study, a randomized crossover trial that pitted a high-EVOO vegan diet against a low-EVOO vegan diet. The results may not be what you think…

    Sign up for my newsletter at www.jrennickemd.com

    Timestamps:

    00:00 - Intro
    02:47 - Methods
    06:16 - Results
    09:13 - Discussion/Nuance
    12:38 - Takeaways
    13:55 - Outro

     

    References:

    Krenek, A. M., Mathews, A., Guo, J., Courville, A. B., Pepine, C. J., Chung, S. T., & Aggarwal, M. (2024). Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin Olive Oil Within a Whole‐Food Plant‐Based Vegan Diet. Journal of the American Heart Association, 13(15), e035034. https://doi.org/10.1161/JAHA.124.035034  

  • Being healthy is really simple. That doesn't mean it's easy, but it really isn't rocket science. Today we walk about the only nine things you need to take care of in order to be healthy.

    Sign up for my newsletter at www.jrennickemd.com

    Timestamps:
    00:00 - Intro
    00:42 - #1 Eat A Health Promoting Diet
    05:13 - #2 Get Enough Physical Activity
    09:47 - #3 Get Enough Sleep
    11:34 - #4 Maintain A Healthy Body Composition
    15:58 - #5 Maintain A Healthy Blood Pressure
    19:28 - #6 Avoid Tobacco and Other Harmful Substances
    25:18 - #7 Maintain Healthy Blood Sugars
    32:13 - #8 Maintain Healthy Cholesterol Numbers
    34:59 - #9 Build Resilient Mental Health
    38:51 - Outro

     

  • Is high protein intake damaging your kidneys? In this evidence-based video we break down the science behind protein consumption and kidney health.

    What you'll learn:
    • The truth about protein intake and kidney function
    • How your kidneys process protein
    • Latest research on protein consumption and kidney health
    • Different effects of animal vs. plant protein
    • Safe protein intake recommendations

    Timestamps:
    00:00 - Intro
    00:58 - Why Do We Care?
    01:56 - Kidney Basics
    04:47 - Mechanistic Plausibility
    07:50 - Sources of Protein
    09:03 - Review Paper- Protein Intake and CKD risk
    13:02 - Paper 2: Protein intake in patients with CKD
    17:39 - Takeaways
    17:60 - Outro


    💡 For more evidence-based health and fitness content, subscribe to my Youtube Channel

    References:

    Carballo-Casla 2024: https://doi.org/10.1001/jamanetworkopen.2024.26577   Cheng 2024:  https://doi.org/10.3389/fnut.2024.1408424   Devries 2018: https://doi.org/10.1093/jn/nxy197
    Van Elswyk 2018:. https://doi.org/10.1093/advances/nmy026  


    About Jordan Rennicke:
    Board-certified in both Family Medicine and Sports Medicine, dedicated to keeping you active and healthy for life through actionable, evidence-informed education.

  • In this podcast we cover two articles that were recently published. We cover an article on how the frequency of lifestyle interventions may play a role in improving long term weight loss, and how the AHA's Life's Essential 8 is still very important in patients with obesity.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: https://www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    00:38 - Lifestyle Interventions for Weight Los
    01:20 - Methods
    02:08 - Results
    05:20 - Discussion
    09:29 - Life’s Essential 8 and Obesity
    10:25 - Simple 7 vs Essential 8
    11:21 - Study Setup
    13:26 - Findings
    17:31 - Key Findings
    19:52 - Limitations
    20:15 - Takeaways
    20:49 - Outro

    REFERENCES:

    Lifestyle and Weight Loss: https://doi.org/10.1016/j.eprac.2024.08.015   Essential 8 with Obesity: https://doi.org/10.1136/bmjopen-2019-029966 AHA Essential 8 Calculator:https://mlc.heart.org/assessment  


    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • 🔍 In this episode of Building Lifelong Athletes, we talk about:

    - 📊 Chronic Pain & Exercise: Discover why movement might be the key to managing chronic pain, even when it's the last thing you want to do. Learn about the latest research and what it means for your health journey.
    - 🥗 Weight Loss & Macros: We break down a fascinating study that looks at whether high-protein or high-carb diets work better for weight loss. The results might surprise you!

    ⏰ Timeline:

    00:00 - Intro
    00:54 - Chronic Pain Study Overview
    01:28 - Physical Activity vs Exercise
    02:53 - Study Methods
    03:19 - Results
    06:49 - Limitations/Future Research
    07:56 - Takeaways
    09:47 - Macros For Weight Loss Article Intro
    10:21 - IMPROVE Study Design
    14:17 - Results
    15:42 - Significance
    16:21 - Strength and Limitations
    16:44 - My Takeaways
    18:52 - Outro

    References:

     https://doi.org/10.1002/14651858.CD011279.pub3 https://doi.org/10.3390/nu16172842  

    🔔 Stay informed! Sign up for our evidence-based health newsletter at [www.jrennickemd.com](http://www.jrennickemd.com)

     

  • In today's podcast we are talking about the recent news of the death of the United Healthcare CEO and my response to the public's reaction.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: https://www.jrennickemd.com

    CHAPTERS:
    00:00 - Intro
    00:48 - Background
    01:39 - The Public’s Response
    03:13 - Healthcare Workers Perspectives
    06:10 - Why Did This Happen?
    07:52 - What Can We Do To Fix Healthcare?
    10:56 - Outro


    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • In today's podcast we talk about whether GLP-1 agonists like Semaglutide can be helpful for osteoarthritis, and we look at the true link between physical activity and cardiometabolic health.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.
    Click Here: https://www.jrennickemd.com/#/portal/signup

    CHAPTERS:
    00:00 - Intro
    00:15 - Article 1: GLP-1 for Knee Osteoarthritis
    00:51 - Overview
    01:56 - Design
    02:59 - Weight Loss Results
    03:59 - Pain Reduction Results
    05:02 - Safety
    06:20 - Mechanism of Action
    07:15 - Takeaways
    10:00 - Article 2: PA, CRF, and metabolic health
    10:11 - Background
    11:37 - Previous Research
    12:56 - Study Design
    15:04 - Marker 19
    19:26 - Importance of Exercise Intensity
    20:20 - Strengths and Limitations
    21:12 - Clinical Implications
    21:60 - Outro

    References:

    Bliddal, H., Bays, H., Czernichow, S., Hemmingsson, J. U., Hjelmesæth, J., Morville, T. H., Koroleva, A., Neergaard, J. S., Sánchez, P. V., Wharton, S., Wizert, A., & Kristensen, L. E. (2024). Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis. New England Journal of Medicine, 391(17), 1573–1583. https://doi.org/10.1056/NEJMoa2403664   Fridolfsson, J., Ekblom-Bak, E., Ekblom, Ö., Bergström, G., Arvidsson, D., & Börjesson, M. (2024). Fitness-related physical activity intensity explains most of the association between accelerometer data and cardiometabolic health in persons 50–64 years old. British Journal of Sports Medicine, 58(21), 1244–1250. https://doi.org/10.1136/bjsports-2023-107451  


    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • America is in a health crisis. We're overwhelmed by chronic diseases, grappling with concerns about the safety of our food and environment, and Americans are struggling to trust the very institutions designed to protect us. Robert F. Kennedy Jr., a prominent figure known for his controversial stance on many topics, claims he has the cure. He's calling it 'Make America Healthy Again', and he's promising to revolutionize American health. But, is it all bad? Is MAHA a genuine path to wellness or a dangerous detour down a road paved with misinformation and political opportunism? Join me as we unpack the promises, the politics, and the potential consequences of 'Make America Healthy Again.' We'll separate fact from fiction, explore the science behind the claims, and give you the information you need to make informed decisions about your health and the future of our nation.

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    Click Here: https://www.jrennickemd.com/#/portal/signup

    CHAPTERS:
    00:00 - Introduction
    00:32 - What is MAHA?
    01:37 - The 5 Pillar
    02:23 - The Good
    04:03 - The Bad
    06:05 - My Take
    10:18 - Moving Forward
    11:14 - Optimism
    12:29 - Outro


    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • In this episode we talk about a common hip condition that is seen in younger athletes in the primary care setting called Femoroacetabular Impingement (FAI). We talk about the basics, and how to recognize this condition.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life. Click Here: https://www.jrennickemd.com/

    Timestamps:

    00:00 - Introduction
    00:22 - Video Intro
    01:33 - What is FAI?
    02:10 - How Common is FAI?
    03:01 - Imaging
    04:41 - Symptoms
    05:33 - Diagnosis
    05:51 - Imaging
    07:08 - Alpha Angle
    09:12 - LCEA
    10:27 - Physical Exam
    13:05 - Treatment
    17:08 - Summary
    18:30 - Outro

    *Disclaimer* This video is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

  • You might be searching for information on cholesterol and run across the idea of cholesterol ratios. There are a lot of claims on the internet that cholesterol ratios are the most important thing you can look at to determine your risk for developing cardiovascular disease... but is that accurate? Today I'll take you through the science behind the ratios, and how to use them properly.

    Sign up for my free newsletter to receive analysis, reviews, and my interpretations of the most recent research to help you stay and active for life.

    CHAPTERS:
    00:00 - Intro
    00:23 - Why Do We Care?
    01:16 - Lipid Biochemistry
    06:28 - Cholesterol Ratios Basics
    09:35 - The HDL Problem
    11:27 - Ratios Explained
    16:17 - The Factory Analogy
    18:59 - Ratios in the setting of the factory analogy
    23:06 - Why are elevated triglyerides a problem?
    26:30 - TG:HDL Ratio Recap
    30:47 - Outro


    *Disclaimer* This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.