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  • This week I spoke with Bogdan Knezevic, founder of Kaleidoscope Bio, about optimizing biotech workflows and achieving milestones efficiently. Bogdan shared insights into how his platform helps companies manage research and development processes, reducing operational inefficiencies and saving time, resources, and money. He discussed the importance of setting clear goals, breaking down complex workflows, and avoiding shiny object syndrome (a common ailment among scientists). Bogdan also emphasized the value of keeping teams focused and aligned, leveraging automation, and integrating existing tools to minimize manual work. We explored how to empower teams, balance short-term and long-term goals, and pivot gracefully when needed. Additionally, Bogdan touched on the importance of understanding the true cost of operations and making strategic investments in tools that drive productivity.

    Exhalation: StoriesGet Bogdan's recommended book! Stories of Your Life and OthersBiotech inflection points framework resource:Biotech fundraising milestones resourceLearn more about Kaleidoscope!Link In with Bogdan!

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    00:00 Introduction to Systems and Workflow

    01:10 Meet Bogdan Knezevic: From Childhood Dreams to Biotech CEO

    02:22 The Frustration and Vision Behind Kaleidoscope Bio

    04:01 Use Cases and Value Propositions for Biotech Companies

    07:50 Empowering Teams and Setting Priorities

    11:38 Balancing Short-Term and Long-Term Goals

    18:22 Reducing Operational Overhead and Streamlining Processes

    31:07 Common Mistakes and Lessons for Biotech Leaders

    36:19 Book Recommendations and Closing Thoughts

  • This week I spoke with Jon Hu, CEO and co-founder of Pepper Bio, about his journey from pharma consulting and venture capital to founding a tech-enabled biotech company. Pepper Bio created an AI and machine learning platform accelerating drug discovery for untreatable diseases. In addition to the platform, Pepper is currently navigating their asset for liver cancer into phase 2 clinical trials. Jon highlighted the differences between tech and biotech, emphasizing the importance of dreaming big and aligning vision with employees. He shared insights on the importance of hiring, learning to learn, and overcoming challenges in transitioning from tech-enabled discovery to drug development. We also discussed Pepper Bio's computational platform, long-term strategy, and their Series A fundraising to support their clinical trial efforts. Jon’s personal story of family health challenges driving his passion for biotech underscored the company's mission to transform patient care.

    Start with Why: How Great Leaders Inspire Everyone to Take ActionGet Jon's recommended book! What Do You Do With an Idea? New York Times best sellerLearn more about Pepper BioLink In with Jon!

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    00:00 Introduction to John Hu and Pepper Bio

    00:54 John's Early Aspirations and Career Path

    02:27 Founding Pepper Bio and Its Mission

    05:15 Tech vs. Biotech: Ambitions and Challenges

    10:42 Project Optimist and Pepper's Role

    11:53 Pepper's Computational Platform and Future Goals

    16:14 Navigating the Biotech Industry and Hiring Strategies

    33:35 Personal Motivations and Future Aspirations

    36:03 Book Recommendations and Closing Remarks

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  • This week we chatted with Cheri Ackerman, PhD, Cofounder & CEO of Concerto Biosciences. During her postdoctoral work at MIT, she developed the groundbreaking kChip technology that led to the formation of Concerto Biosciences. We discuss the challenges and opportunities of building a company during the pandemic and the importance of learning the business side of biotech as a scientific founder. As always, we trumpet the value of building a network to leverage during the growth process. Cheri gives really great advice for aspiring entrepreneurs, which is to keep learning and embrace asking questions when you don’t know something. I also loved her views on adapting and experimenting in business, which is one of the key values at Concerto. 

    00:00 Introduction and Early Career Aspirations

    00:09 Journey to Becoming a CEO

    01:12 Founding Concerto Biosciences

    02:31 Understanding the Microbiome

    04:56 Concerto's Innovative Approach

    07:53 Challenges and Opportunities in Building a Company

    08:58 Navigating the Funding Climate

    13:00 Building a Strong Team

    21:57 Advice for Aspiring Entrepreneurs

    29:34 Future Goals and Aspirations

    31:55 Conclusion and Contact Information

    Get Cheri's recommended books! Measure What MattersThe Founder's Dilemmas: Anticipating and Avoiding the Pitfalls That Can Sink a Startup (The Kauffman Foundation Series on Innovation and Entrepreneurship, 13)No Rules Rules: Netflix and the Culture of ReinventionGood to Great: Why Some Companies Make the Leap...And Others Don'tWhoLearn more about Concerto BiosciencesLink In with Cheri!

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  • This week I sat down with Krysta Pellegrino, Chief Client Officer at Health+Commerce, a public relations and marketing agency specifically focused on healthcare. Krysta shared her unique perspective on how biotech companies can leverage communications strategies to tell their stories effectively, attract talent, and navigate complex challenges. She offered insights on the importance of integrated communications, the evolving landscape of media, and how agencies like H+C can help startups and established companies alike build their brands and communicate their innovations. We also touched on the importance of media training, investor pitch decks, and future trends in biotech communications, including the growing role of AI and integrated digital strategies.

    00:00 Introduction and Guest Welcome

    00:15 Early Career Aspirations and Path

    01:03 Journey in Healthcare Communications

    03:23 Role and Impact of PR in Biotech

    05:40 Talent Acquisition and Company Culture

    07:43 Leveraging Social Media and Video

    10:52 Strategies for Startups and Established Companies

    18:16 Investor Relations and Pitch Decks

    22:02 Media and Presentation Training

    27:01 Future Trends in Biotech Communications

    31:37 Crisis Management and Scenario Planning

    35:19 Conclusion and Final Thoughts

    Get Krysta's recommended book: An Instance of the FingerpostLearn more about Healthcare Digital Marketing Agency | Health+CommerceLink In with Krysta!

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  • In this episode, I had the privilege to interview Bonnie Bertolaet, Ph.D, Executive Director of Science Club for Girls, and Ashley Cooper, MS, MPhil, Curriculum Writer and Evaluation Manager at Science Club for Girls and former Co-Director of the Harvard Chapter of Science Club for Girls. Science Club for Girls aims to ignite excitement, confidence, and literacy in STEM among girls and gender-expansive youth from underrepresented communities. Bonnie and Ashley shared insights into how the organization operates, from engaging young students through hands-on activities to providing valuable mentorship opportunities for biotech employees. They discussed the importance of starting STEM education early, the transformative impact of mentorship, and the ways companies can get involved and contribute. Success stories and the personal experiences of the guests offered a powerful testament to the program's effectiveness in fostering a diverse and inclusive pipeline for future scientists.

    Link In with Ashley!Learn more about Science Club for GirlsLink In with Bonnie!

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    00:00 Introduction to the Episode

    00:51 Meet the Guests: Bonnie and Ashley

    02:37 What is Science Club for Girls?

    03:47 Engaging Young Minds in STEM

    10:26 Mentorship and Corporate Engagement

    21:06 Success Stories and Impact

    23:16 Virtual Clubs and Future Expansion

    26:22 How to Get Involved and Support

    32:01 Recommended Reads and Final Thoughts

  • In this episode, we had the pleasure of welcoming back Lynn Walder, our first repeat guest, to dive into the pitfalls and best practices of defining culture and core values for growing companies. There has been a shift in how companies invest in and operationalize culture over the past two decades. Lynn shares insights from her extensive experience, including the importance of early core value implementation, the challenges of aligning leadership actions with stated values, and the need for clear communication and accountability. We also discuss various assessments Lynn uses to help biotech companies define and uphold their foundational values, and how these values guide companies through times of change and crisis.

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    00:00 Introduction and Welcome Back

    00:34 The Evolution of Culture in Biotech

    03:01 Defining and Implementing Core Values

    05:52 Challenges in Aligning Leadership with Core Values

    10:27 The Importance of Early Implementation

    16:32 Assessments and Frameworks for Leadership

    23:59 Operationalizing Values in Biotech

    37:49 Transparency and Communication in Leadership

    39:58 Conclusion and Contact Information

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    lynn walder intro

  • Today, I had the opportunity to speak with Amogha Tadimety, PhD, CEO, and Alison Burklund, PhD, President & CTO, co-founders of Nanopath, an innovative company specializing in women’s health diagnostics. Both hailing from Dartmouth’s Thayer School of Engineering, Amogha and Alison walk us through the challenges and opportunities of founding a diagnostic company during the COVID era. We chatted about the intricacies of bringing foundational technology to consumers, including the importance of navigating the insurance system and the specific focus of their technology on improving point-of-care diagnostics in women's health. They highlighted the need for innovative tools in OB-GYN practices, the strategic decisions that shaped Nanopath's direction, and the significant milestones they have achieved. They also emphasized the importance of building a strong team and network, overcoming healthcare system challenges, and their vision for the company's future, which includes creating a comprehensive well-woman panel and expanding the technology for broader applications.

    Get Alison's recommended book: The Fourth Turning is hereGet Amogha's recommended book: Remarkably Bright Creatures: A Read with Jenna PickLink In with Alison!Link In with Amogha!

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    00:00 Introduction to Nanopath Founders

    00:59 Career Paths and Early Inspirations

    01:42 The PhD Innovation Program

    02:16 Founding Nanopath: The Journey Begins

    04:58 Nanopath's Mission and Technology

    08:13 Navigating the Healthcare System

    10:14 Challenges and Opportunities During COVID-19

    16:05 Building a Strong Team and Network

    24:02 Future Vision and Goals

    25:38 Reading Recommendations and Closing Thoughts

  • In this episode, I sat down with Ben Hemani from Bison Ventures, a venture capital firm that invests in early-stage frontier technology companies. We explore his background in environmental engineering and his transition into the venture capital world, driven by a passion for technology and sustainability. Ben elaborates on the interconnected areas Bison Ventures invests in, such as biotech, high-performance computing, and climate sustainability, emphasizing the critical role cross-pollination plays in innovation. We explore the nuances of assessing early-stage companies, focusing on the importance of founder teams, technical maturity, and long-term planning. Ben also shares insights on the current funding landscape and the strategic support Bison Ventures offers its portfolio companies.

    Get Ben's favorite book at the moment! Expecting Better (The ParentData Series Book 1) by Emily OsterLink In with Ben!Bison Ventures

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    00:00 Introduction to Ben Hemani and Bison Ventures

    00:34 Ben Hemani's Background and Career Path

    02:48 Transition into Venture Capital

    04:37 Overview of Bison Ventures

    06:13 Investment Strategies and Challenges

    14:49 Supporting Founding Teams

    19:11 Life Cycle of Portfolio Companies

    23:07 Current Trends and Future Prospects

    25:34 Day in the Life of a VC

    27:05 Personal Insights and Recommendations

    28:21 Conclusion and Contact Information

  • This week I sat down with Krisha Panchalingham, Director of Lab and Scientific Operations at Portal Innovations. Krisha shares how she and her team support early-stage biotech companies through the operational intricacies of setting up labs, handling logistics, maintaining equipment, and complying with regulations. We also discuss the importance of vendor management, the role of external consultants, and the strategic partnerships required to efficiently run lab operations. Krisha also emphasizes the significance of mentorship and the strategic role of operational support in the success of biotech startups. We also discuss how Portal Innovations fosters a nurturing ecosystem for biotech startups, underscoring the balance between scientific discovery and operational excellence.

    Get Krisha's recommended book! A Walk in the Woods: Rediscovering America on the Appalachian Trail (Official Guides to the Appalachian Trail)Boston Globe: The promise of biotech jobs is coming to Boston’s neighborhoods - MassBioLink In with Krisha!Portal Innovations LLC

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    00:00 Introduction to Krisha Penchalingham and Portal Innovations

    00:57 Krisha's Journey: From Childhood to Biotech

    03:58 Role and Responsibilities at Portal Innovations

    04:24 Supporting Early-Stage Biotech Companies

    06:20 Challenges and Successes in Lab Operations

    07:47 Team Dynamics and Growth at Portal Innovations

    08:28 Expanding Ecosystems and Future Plans

    22:26 Mentorship and Career Advice

    27:31 Conclusion and Contact Information

  • This week, Carina Clingman, PhD, Founder and Principal of Recruitomics Consulting, outlines an actionable 3-Step framework to simplify the recruitment process and hire top-quality talent. The discussion covers common challenges faced by small companies, such as desperation hiring and inefficiencies, and offers solutions like implementing applicant tracking systems (ATS), streamlining processes, and leveraging data-driven hiring. The episode also emphasizes the significance of proper training and compliance in conducting fair and effective interviews. Listeners will learn how to audit current processes, install a sustainable hiring engine, and ensure they attract and select the best talent, even on a limited budget.

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    00:00 Introduction: The Importance of Talent in Biotech

    00:54 Why Systems Matter in Talent Acquisition

    02:05 Common Challenges in Small Companies

    04:20 The Concept of Chicken Math in Startups

    07:58 Auditing Your Hiring Process

    09:31 Building a Sustainable Hiring Engine

    10:54 The Role of Applicant Tracking Systems

    19:08 The Importance of Training and Legalities

    24:31 Data-Driven Hiring Decisions

    31:42 Conclusion: Implementing Effective Hiring Strategies

  • This week I chatted with Oriana Papin-Zoghbi, CEO and co-founder of AOA Dx. Oriana shares insights on the challenges of fundraising and the importance of building a network for startup success. She highlights her career shift from biochemistry to economics and international relations, finally leading to her involvement in women's health diagnostics. Oriana emphasizes the significance of finding one's passion for excelling in their field and the role of previous startup successes in her current venture. I also loved learning more about AOA Dx's mission to revolutionize women's health diagnostics, focusing on unmet needs such as early ovarian cancer detection through innovative biomarker research. Oriana highlights the impact of leadership, resilience, and the pursuit of innovation in healthcare.

    Get Oriana's recommended book! Shoe Dog: A Memoir by the Creator of NikeLink In with Oriana!AOA DX – Early cancer detection

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    00:00 Introduction to Oriana Papin-Zoghbi and AOA DX

    00:37 Oriana's Journey: From Aspiring Doctor to Women's Health Innovator

    04:06 Challenges and Triumphs in Women's Health Innovation

    07:38 The Founding of AOA DX: A Mission to Transform Women's Health

    07:57 Lessons Learned from Successful Exits and Setting Up AOA DX

    09:28 AOA DX's Vision and Mission: Advancing Women's Health Diagnostics

    12:57 Fundraising Journey: Overcoming Skepticism and Building Trust

    15:21 Leveraging Business Development Skills in Fundraising

    16:31 Y Combinator Experience and the Value of Community

    18:23 Advice for Aspiring Founders in Women's Health

    20:29 Future Plans for AOA DX and Personal Aspirations

    23:48 Oriana's Reading Recommendations and Closing Thoughts

  • This week, I chatted with leadership advisor, speaker, entrepreneur, and podcast host Tony Martignetti, MBA, CPC, Founder, and Chief Inspiration Officer of Inspired Purpose Partners. We both agree there’s a critical need for more comprehensive coaching and support for leaders in the biotech industry. Drawing from his diverse career that spans from art to finance and biotech, Tony shares insights into how leaders can become more grounded. He highlights his three Cs of grounded leadership - Connection, Curiosity, and Compassion - and underscores the significance of mental health, adapting to rapid change, and maintaining authenticity in the workplace. These qualities, he argues, are paramount for building strong companies and navigating the complexities of leadership in fast-evolving sectors like biotech.

    Get Tony's favorite book: The Art of Possibility: Transforming Professional and Personal LifeTony Martignetti: books, biography, latest updateFollow Tony on Social!Inspired Purpose PartnersLink In with Tony!Ted TalkPodcast - Inspired Purpose PartnersCampfires of Connection - Inspired Purpose Coaching

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    00:00 Introduction to Tony Martignetti: A Multifaceted Leadership Advisor

    00:11 The Importance of Leadership Coaching in Biotech

    00:57 Tony's Journey: From Childhood Dreams to Leadership Advisory

    02:37 The Pivotal Shift: Embracing Leadership Advisory After Burnout

    04:42 Addressing Burnout: Personal Insights and Industry Observations

    08:06 Navigating Post-Pandemic Challenges and Emphasizing Connection

    11:11 The Three Cs of Grounded Leadership: Connection, Curiosity, Compassion

    25:17 Incorporating Experience Design in Leadership Coaching

    27:58 Campfire Lessons for Leaders: Tony's Book and Vision for the Future

    35:44 Final Thoughts and Resources for Aspiring Leaders

  • In this episode, Heather E. Williams, PhD, MBA, MS, PgD, ErCLG, CG (ASCP) MB, the Chief Operating Officer of Cache DNA, chats about her career journey and the importance of always learning. Heather's passion for medicine and genetics has led her from childhood dreams of being like Dr. Quinn, Medicine Woman to training as a clinical laboratory geneticist and eventually becoming a COO. She talks about the value of making connections, grabbing every chance to learn, and how genetic results can really make a difference in patient care. Tune in to hear more about Heather's career story and get a sneak peek into what she does at Cache DNA.

    Get Heather's favorite book: The Poisonwood Bible: A NovelLink In with HeatherCache DNA

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    00:00 Introduction and Guest Overview

    00:30 Heather's Early Career Aspirations

    01:28 Current Role at CacheDNA

    02:34 Building and Leading a Team

    03:36 Transition to Flagship and Executive MBA

    07:27 Gene Between and Endless Frontier Labs

    11:28 Networking and Mentorship Insights

    21:29 Challenges in Precision Medicine

    28:27 Future Goals and Book Recommendations

    30:46 Conclusion and Contact Information

  • This week, we had a conversation with Catharine Smith - the Executive Director at the Termeer Foundation. Catharine is passionate about supporting biotech founders in growing patient-centric companies. We are thrilled about the Termeer Foundation and have been delighted to witness the Termeer Fellows thrive through the support, training, and community that this organization provides. If you're interested in making a difference in human health through biotech, this episode is definitely for you.

    Get Catharine's favorite book: The Covenant of WaterLink In with CatherineThe Termeer Foundation

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    00:00 Introduction to Catherine Smith and the Termeer Foundation

    00:20 Catherine's Early Career and Passion for Healthcare

    01:57 Role and Mission of the Termeer Foundation

    04:04 Challenges and Support for Early Stage Biotech Leaders

    06:56 Day-to-Day Life as Executive Director

    08:56 Previous Experience at the Clinton Health Matters Initiative

    11:46 The Termeer Fellows Program

    13:48 Common Challenges for First-Time Founders

    16:36 Global Reach and Diversity in Biotech

    23:06 Nonprofit Career Insights and Mentorship

    31:31 Future Aspirations and Book Recommendations

    34:54 Conclusion and How to Connect with Catherine

  • In this episode, we chatted with Isaac Stoner, M.B.A., the CEO of Octagon Therapeutics. Isaac is known for his expertise in building small companies and embarking on adventurous missions such as recovering airplane black boxes (yes, you read that correctly!). He also hosts a science enthusiast networking group in Cambridge, where attendees drink beer and discuss science.

    Link In with Isaac!Isaac's favorite book: Children of TimeIsaac's favorite book: A Heart That WorksGet Isaac's favorite book: The Song of the Cell: An Exploration of Medicine and the New HumanOctagon Therapeutics

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    00:00 Introduction and Background

    02:41 Isaac's Early Aspirations and Career Path

    05:17 Insight into Octagon Therapeutics

    08:20 Company Focus and Structure

    13:00 Guidance on Business Operations and Growth

    16:13 Networking and Community Building

    19:37 Industry Trends and Future Prospects

    25:23 Fundraising Strategy and Advice

    30:02 Building an Effective Board

    34:12 Managing Company Growth and Exit Strategies

    38:00 Long-term Plans and Personal Goals

    40:10 Book Recommendations and Closing Thoughts

  • This week we sat down with Kyriakos Economides, PhD, VP of Translational  Pharmacology at Werewolf Therapeutics. If there’s one constant in biotech, it’s change. We discussed the evolution of a career, rolling with the punches, and the importance of a solid clinical plan early in the drug development lifecycle. 

    Kyriakos's favorite book: The Emperor of All Maladies: A Biography of CancerGet Kyriakos's favorite book: The Lost Empire of Atlantis: History's Greatest Mystery RevealedWerewolf Therapeutics Inc.Linked In with Kyriakos

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  • This week, we had an insightful conversation with Leen Kawas, PhD, Managing General Partner at Propel Bio Partners. She shared her journey from studying pharmacy to founding a successful company (with a great exit) and now running a venture fund. She emphasizes the business case for the importance of DEI in the company leadership and in clinical trials. We also touched on tips on managing conflict in teams, fostering healthy communication, and the value of building a strong network and connections in the industry.

    Get Leen's favorite book: The Boys in the Boat: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin OlympicsPropel Bio PartnersLink in with Leen!

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    00:00 Introduction and Guest Overview

    00:42 Early Aspirations and Career Path

    02:46 Transitioning from Academia to Entrepreneurship

    04:03 Founding a Fund and Supporting Companies

    05:03 Day-to-Day Life and Global Interactions

    07:54 Building and Managing Effective Teams

    13:11 The Importance of Diversity in Clinical Trials

    18:53 Navigating the Current Economic Environment

    25:12 Conflict Management and Effective Communication

    31:10 Networking and Future Goals

    36:05 Conclusion and Final Thoughts

  • This week, we had the pleasure of chatting with Andrew Fraley, PhD, Entrepreneur in Residence with Atlas Venture. We chatted about his journey from bench chemist to entrepreneur, and some of the things he learned in the process. He also shared valuable insights on structuring a pitch deck for those on the funding trail. Tune in to learn from Andrew's fascinating experiences and fantastic advice!

    Get Andrew's favorite book: Storytelling with Data: A Data Visualization Guide for Business ProfessionalsAtlas Venture - We build breakthrough biotechnology companies.Link In with Andrew!

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  • In this episode, Rikin Mehta, Pharm.D., J.D., LL.M. co-founder of Lactiga and co-founder and CEO of Licentiam, discusses the importance of looking at biotech through a regulatory lens. Rik shares insights on the significance of regulatory knowledge across an organization and reflects on how his diverse career journey helped shape his outlook on building solid companies. He shares how regulatory knowledge plays a vital role in every aspect of the organization, and how you can apply that knowledge to your company.

    Get Rik's favorite book: A Tale of Two CitiesLicentiamLactigaLink In with Rik!

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  • This week we sat down with Sarah Hein, PhD, co-founder and CEO of March Biosciences. She shares her journey from academia to entrepreneurship, the story of her first company and successful exit, and how she’s leveraging strategic partnerships to grow her current company. She also gave some actionable frameworks for early-career founders. Tune in to learn about her experience working with a venture fund and launching two exciting startups.

    Sarah's favorite book: For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster DrugGet Sarah's favorite book: We Are Legion (We Are Bob) (Bobiverse Book 1)March BiosciencesLink In with Sarah!

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