Avsnitt
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What actually happens after you sell a company for $1.1B and never need to work again?
Joe DeVivo is a legendary MedTech CEO who sold InTouch to Teladoc in a $1.1B deal and is now President, CEO, and Chairman of Butterfly Network.
Joe has a very specific reputation in the industry. He steps in when companies get stuck. Often at the moment when a founder-led business needs a different kind of leadership to scale. In this episode, Joe breaks down his turnaround playbook step by step, from how he diagnoses what’s broken, to who stays, who goes, and how focus gets restored.
He also opens up about something that’s rarely talked about. What it really feels like after a massive exit. When the money hits, the anxiety leaves your body, and you realize you never have to work again. What does “post-economic” life actually look like, and why do some people still choose to come back?
We also trace Joe’s path from growing up in a family-run manufacturing business to becoming the CEO boards call in moments of crisis, and why invention and scaling are fundamentally different jobs.
Links
Butterfly Network: https://www.butterflynetwork.com
Dr Mustafa Sultan: https://www.musty.io
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In 2023, Alexandre Lebrun pointed two exits in conversational AI at Medicine. Nabla raised $120M and spread to 130+ orgs and 85,000 clinicians in record time.
But in the ambient AI game -- it seems like distribution beats all. How will Nabla win?
Links
Nabla: https://www.nabla.com/
Dr Mustafa Sultan: https://www.musty.io
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Saknas det avsnitt?
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In 2017, Andrew Parker launched Papa with a 1-800 number, offering 'grandkids-on-demand' in Miami. By 2021, the company was valued at $1.4bn (backed by SoftBank and Tiger Global).
This is a YC-backed gig economy company operating in the regulated elder care market at unicorn scale.
On paper it shouldn't have worked -- and yet it did.
Links
Papa: https://www.papa.com/
Dr Mustafa Sultan: https://www.musty.io
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According to Business Insider, Omada Health has quietly filed its S-1 to prepare for an IPO. Here's how Sean Duffy (CEO & Co-founder) built it.
0:00 Intro
0:17 Signing first customer
1:51 How to have good ideas in healthcare
4:00 Why metabolic health is a hard area to innovate in
5:18 What the MVP product looked like
11:16 Sean's secret tactics
14:55 Operational innovation as a differentiator
20:19 The Omada playbook — is it repeatable?
25:31 What boss moves have you made Sean?
29:37 The difference between good and great
32:29 Sean's best tip on selling in enterprise healthcare
33:35 Sean's advice to himself
Links
Omada Health: https://www.omadahealth.com
Dr Mustafa Sultan: https://www.musty.io
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Dr Aengus Tran is the CEO of Harrison.ai — an Australian radiology AI startup who have raised $160M.
Harrison.ai just released their radiology foundation model, Harrison.rad.1. And it's really good.
0:00 Intro
2:25 I'm glad I didn't found my startup in the US
4:21 Partnering with a clinical operator is key
7:28 Scrappy stories from the early days
11:17 Where human radiologists outperform AI (zero-shot learning)
17:23 Big bets on the future of radiology
21:18 What happens when GPT-8 arrives?
25:29 How can AI reach suprahuman radiology performance?
28:58 What boss moves did you make?
Links
Harrison.ai: https://harrison.ai
Dr Mustafa Sultan: https://www.musty.io
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Michael Meucci (CEO) transformed Arcadia — formerly a mid-sized consultancy into a healthcare platform with $100M of Annual Recurring Revenue. How?
Lots of smart moves, including becoming really good at enterprise healthcare selling. Here's how he did it.
Links
Arcadia: https://arcadia.io/
Dr Mustafa Sultan: https://www.musty.io/
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Dr Elina Berglund is the CEO/Co-founder of Natural Cycles, which she has grown to 2M users. When every other app seemed to be free — she made a brave decision: She charged her users a monthly fee. And it worked...
0:57 - The Birth of Natural Cycles2:57 - The Decision to Charge from the Start3:47 - Building Trust Through Pricing4:23 - From Personal Struggles to Public Solution5:52 - Creating the Fail-Safe Algorithm6:32 - Collaboration with CERN Colleagues7:13 - The Human Body: Complex Beyond Measure8:37 - The Promise and Challenge of Wearables10:16 - Understanding User Behavior11:04 - Gaining Regulatory Approval12:26 - Secrets to Growth and Marketing13:43 - The Challenge of Direct-to-Consumer Healthcare16:02 - Data-Driven Decision Making17:13 - Instincts Versus Data19:01 - Staying Honest with Data21:20 - Calibrating Communication for Investors22:30 - Benefits of Being Profitable24:08 - Data as a Superpower24:59 - Overcoming Negative PR27:13 - Future of Contraception29:30 - Impact of Roe v. Wade Overturning
Links
Natural Cycles: https://www.naturalcycles.com/
Dr Mustafa Sultan: https://www.musty.io/
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Konstantin started Kaia Health after paying $50,000 to cure his back pain at an elite pain rehab centre. It worked. But it seemed stupid. Why did this need to cost $50,000?
Kaia Health has since raised $125M and helped 625,000 users.
0:00 The 90 second story
1:22 How did he grow 20% every week?
2:15 Market timing is everything
7:43 We never put pressure on this making any money
10:51 How does an app cure back pain?
14:43 US vs Germany for digital health entrepreneurs
16:40 Go to market of Kaia Health
19:51 Why raise so much money?
24:57 The hero license
Links
Kaia Health: https://kaiahealth.com/
Dr Mustafa Sultan: https://www.musty.io/
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Jon Ronson is one of the most interesting people alive today — period.He’s the author of the Men Who Stare at Goats, So You’ve Been Publicly Shamed and The Psychopath Test — which spent 10 weeks on the New York Times bestseller list.His two Ted talks have been watched 20 million times, his books have been brought to life by George Clooney on the big screen, he has written screenplays for Netflix blah blah blah.Don’t believe me, listen to a pitch Jon wrote for ‘the Psychopath Test’. If you are not dying to hear what happens next — then, I don’t what to tell you…
0:00 Jon's pitch for the Psychopath Test
1:41 Jon's story
6:00 Strategies Jon used to bypass career gatekeepers
7:03 Would Jon Ronson be on Substack/podcasting
12:05 Does Jon Ronson pay attention to analytics? Post mortems
16:26 Startup philosophy applied to storytelling
19:08 Writing Advice from Tim Ferriss: Jon's opinion on doing interesting things to write better
24:59 Does Jon Ronson like being famous?
28:49 Analysis of 'The Psychopath Test' pitch to Ira Glass
37:30 Should you make decision based on what would be a good story
38:48 Jon Ronson's habits for creative success
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Max Parmentier is the CEO of Birdie, a Series B AgeTech startup who have raised $52M from the likes of Sofina, Omers Ventures and Index Ventures — and captured 10% of the UK market whilst currently scaling into Europe.
0:00 Intro
2:37 Shopify vs Amazon model in AgeTech
7:26 Product pivots: D2C never wins
11:56 Predictive AI AgeTech
13:58 I pitch an idea to Max
19:34 Lessons building Birdie
24:13 Leaving money on the table for purpose
Links
Birdie: https://www.birdie.care/
Dr Mustafa Sultan: https://www.musty.io/
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Tom Wicher is CEO of DrDoctor — who have served over 20M patients and just raised £10M in their recent Series A round. But he spent the first 7 years bootstrapping, and diverged from his colleagues: Opting for the slow and steady gentle disruption path. Why?
0:00 Gentle disruption beats move fast and break things
3:36 Picking a problem in healthcare
5:44 Behavioural change theory
7:52 Stop treating patients like kids
10:30 Systems-level efficiency vs personalisation
13:02 Why don't patients show up for their appointments?
16:02 Overbooking: Learning from airlines
18:54 Carrot or stick: Motivating health behaviors
22:35 There's no big conspiracy in healthcare
26:24 PIFU model of patient booking
28:14 Sometime it's better not to empower patients
31:16 Habits/frameworks that have helped Tom succeed
Links
DrDoctor: https://www.drdoctor.co.uk/
Dr Mustafa Sultan: https://www.musty.io/
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Drug discovery is becoming more expensive and producing less results than ever before (Eroom's Law)—why?One of the ballooning costs are clinical trials. Pharma/biotech often outsource their trials to CROs (contract research organisations).But many CROs are incentivised to make trials as bloated and inefficient as possible. That means more money and less results.Meri Beckwith is building the anti-CRO: Lindus Health—to solve this problem.
0:00 Intro
1:39 The big problem in drug discovery
4:10 Why do CROs exist?
7:24 The incentive problem in drug discovery/CROs
10:57 Pharma are anti-startups
12:11 How much a clinical trial costs
15:11 How can you compete with big CROs?
17:26 Are you going to build your own drug pipeline?
18:56 Lessons from VC to Founder
23:42 Brand/PR/Positioning as a biotech startup
29:03 Billion dollar ideas in bio/health
31:33 Habits that have helped Meri
Links
Lindus Health: https://www.lindushealth.com/
Meri Beckwith: https://twitter.com/meribeckwith
Mithi Thaya: https://www.linkedin.com/in/mithi-thaya/
Dr Mustafa Sultan: https://www.musty.io/
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Rewind.ai just raised their Series A at a valuation of $350M. Investors include Andreesen Horowitz, Reddit’s Alexis Ohanian and OpenAI’s Sam Altman.Rewind sits on your computer and phone, and watches everything you do. Then you can ask it questions like: What was that really great Mediterranean recipe I looked at last month? Or I’ve got a call with a client next week, can you summarise every interaction I’ve had with them?But here’s where it becomes even weirder, powerful.They’ve announced the Rewind Pendant, a small audio recorder that sits on your chest. Rewind will be able to listen in to every conversation you have.You can ask it: What birthday present should I get for my partner? Did they drop any hints? Or how many arguments did we have last year?Pretty Black Mirror, right?Once you get over the ick however, you realise that this is correcting a lagging human function. Just like the cursed amongst us wear glasses; tools like Rewind will repair our broken memories.I spoke to Dan Siroker, Rewind’s founder—0:00 Intro1:54 Lessons from the Obama Campaign3:28 How to use science to make your startup succeed8:21 Privacy concerns17:00 Rewind.ai as a brain-computer interface (BCI)20:27 Forgetting is important for human wellbeing22:26 Societal impacts of perfect memory28:42 Rewind's tech stack31:56 The existential risk of startups using GPT35:21 D2C is harder than B2B37:49 Leadership lessons40:31 Perils of being a second time founder46:44 Is any publicity good publicity?LinksRewind: https://www.rewind.ai/Dan Siroker: https://twitter.com/dsirokerDr Mustafa Sultan: https://www.musty.io/
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People are wearing Apple Watches to their wedding days. Has this whole 'quantified self' movement gone bananas? Is any of this data actually useful?I spoke to Maitham Dib about this. He's building Vital (YC21); a startup which makes all wearable/lab data available to other startups/companies.0:00 Wearable data is mostly useless3:22 The case for wearable data6:37 Wearable data is mostly useless8:06 Wearable data is useful10:16 The big opportunity with wearable/lab data (startups)14:15 Naivety as a superpower (Paul Graham)15:45 Why building Vital is so hard19:31 Pros/cons of an infrastructure play in healthcare20:51 How to enterprise sales24:09 Lessons from YCombinator27:32 The benefits of being an immigrantLinksVital: https://tryvital.io/Dr Mustafa Sultan: https://www.musty.io/
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Dr Jared Dashevsky writes Healthcare Huddle (acquired by Workweek). He's scaled to over 30,000 subscribers. And it was pretty simple.
Here are 12 frameworks that work for healthcare content creation (and mistakes to avoid).
0:00 Intro
1:14 Consistency is king; systematise it
7:40 McKinsey reverse pyramid principle for writing
9:10 You need to have a unique/controversial take
11:41 Content for network building
15:51 Lean startup thinking does not work for content
20:35 Nobody cares about errors
25:52 Injecting personality is a competitive advantage
29:32 Boring content will make you rich
34:13 Don't make a useless audience; acquire data
41:19 Lessons from Jerry Springer
45:18 Hyperoptimisation paradox
48:49 Do things that don't scale
Links
Healthcare Huddle: https://workweek.com/brand/healthcare-huddle/Dr Jared Dashevsky: https://twitter.com/jareddashevskyDr Mustafa Sultan: https://www.musty.io/
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Despite $billions of investment into the sector — there are still no AI discovered drugs on the market. Why?Recursion Pharmaceuticals (NASDAQ: RXRX) is one of the hottest AI drug discovery companies on the market. Especially after NVIDIA's $50M investment into them.Dr Imran Haque (SVP of AI and Digital Sciences) explains why AI drug discovery is so tricky — and when it's arriving.0:00 Intro0:42 Decoding biology (the big idea)2:18 Why is AI drug discovery harder than it looks?4:48 Simulating the Sims (game) vs AI drug discovery6:58 Building data for AI drug discovery14:47 Recursion's successes and failures24:22 The barriers to AI drug discovery26:45 How optimistic should we be about AI drug discovery35:26 Being aggressively generalist for successPeopleDr Imran Haque: https://www.recursion.com/team-members/imran-haqueDr Imran Mahmud: https://www.imranmahmud.com/Dr Mustafa Sultan: https://www.musty.io/
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0:00 NVIDIA's $50M investment into Recursion Pharmaceuticals2:28 NVIDIA is becoming a seed investor3:45 Bull case for Recursion Pharmaceuticals9:20 Recursion's two big acquisitions13:05 How are Recursion going to make money?14:15 Recursion is overhyped19:45 Recursion is unprofitable22:21 Kim Kardashian's full body MRI scan 26:03 Longevity doctor's advice to Kim K31:49 Speculating on Kim K's longevity regime (what she takes)35:00 Outro and feedbackPodcast LinksYouTube: https://www.youtube.com/@bigpicturemedicineApple: https://podcasts.apple.com/gb/podcast/big-picture-medicine/id1500446262Spotify: https://open.spotify.com/show/5707RPmWOJkVZyUHNRSUfS?si=96c7fff6bccb456aPeopleDr Imran Mahmud: https://www.imranmahmud.com/Dr Adam Bataineh: https://twitter.com/DrAdamBat / https://numenor.healthDr Mustafa Sultan: https://www.musty.io/
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Ever waited months for a scan? Scan.com is making getting a scan as easy as booking an Uber. Behind the scenes of the disruptor changing medical imaging forever.0:00 Race to the bottom?1:34 AirBnB 11 star framework9:57 Scan.com looks really easy to build — what's hard about it?12:19 Lessons from working at Deliveroo15:14 How do you make a lot of money?19:41 Buying the domain name Scan.com24:16 How to build a marketplace business27:50 The perils of price transparency30:36 What I would do to build a competitor32:43 You need grit when building a health startup35:46 Billion $ health ideasPodcast LinksYouTube: https://www.youtube.com/channel/UCEzluDRmBTVby0WsO37V-xgApple: https://podcasts.apple.com/gb/podcast...Spotify: https://open.spotify.com/show/5707RPm...PeopleDr Mustafa Sultan: https://www.musty.io/Charlie Bullock: https://scan.com/
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0:00 David Sinclair's controversial claim 1:39 Bull v bear case6:23 David Sinclair's history of exaggerating and profiteering8:34 Adam Neuman's involvement11:40 Raising from unsophisticated investors16:30 Why aren't big pharma interested in longevity?22:45 Cynics are right, optimists get rich25:26 Will a longevity drug be the most valuable therapeutic ever made28:52 Feedback and outroDavid Sinclair's Tweet: https://twitter.com/davidasinclair/status/1679178670743732249?s=20David Sinclair's Research Paper: https://www.aging-us.com/article/204896/textElon Musk Tweet: https://twitter.com/davidasinclair/status/1679504700285104129?s=20Dr Charles Brenner's Critique of Sinclair: https://twitter.com/CharlesMBrenner/status/1679213673771057152?s=20Podcast LinksYouTube: https://www.youtube.com/@bigpicturemedicineApple: https://podcasts.apple.com/gb/podcast/big-picture-medicine/id1500446262Spotify: https://open.spotify.com/show/5707RPmWOJkVZyUHNRSUfS?si=96c7fff6bccb456aPeopleDr Imran Mahmud: https://www.imranmahmud.com/Dr Adam Bataineh: https://twitter.com/DrAdamBat / https://numenor.healthDr Mustafa Sultan: https://www.musty.io/
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0:00 Why not let the builders build? Move fast and break things?
1:56 Why don't you ban people from googling their symptoms?
3:28 Is a disclaimer enough?
5:27 Why are LLMs difficult to regulate?
10:13 Move fast and kill patients — principal agent problem
12:23 People aren't idiots (they are)
14:20 Dr ChatGPT will never work
17:35 Spotting bubbles in healthcare
19:20 How much time does regulation add onto medical device approval?21:40 Can we ever regulate LLMs?
Podcast Links
YouTube: https://www.youtube.com/@bigpicturemedicineApple: https://podcasts.apple.com/gb/podcast/big-picture-medicine/id1500446262
Spotify: https://open.spotify.com/show/5707RPmWOJkVZyUHNRSUfS?si=96c7fff6bccb456a
People
Dr Hugh Harvey: https://www.hardianhealth.com/Dr Mustafa Sultan: https://www.musty.io/
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