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Episode #331. Are you getting the right balance of omega-3 and omega-6 fats in your diet? Join me as I sit down with leading scientists to explore the role these essential fatty acids play in your health. From brain development and cognitive function to heart health and inflammation, we unpack how these fats impact your well-being and address common misconceptions about omega-6 fats.
You’ll hear from top voices in nutrition, including Dr Bill Harris, Dr Joel Fuhrman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Gary Fraser, Dr Phillip Calder, and Dr Kristina Harris. Each expert shares valuable insights into how omega-3s and omega-6s influence everything from cognitive function to heart disease.
We cover:
Introduction to Omega-3 and Omega-6 Fatty Acids (00:00)
What is Omega-6 and Why the Body Needs It (01:06)
What is Omega-3 and Do We Really Need It? (12:29)
The Importance of Optimising Omega-3 Consumption (42:50)
Understanding DHA and EPA: Why Are They Essential? (50:01)
Are Omega-3s the Most Important Fatty Acids for Brain Health? (55:44)
APOE4 and Omega-3 Supplementation: What You Need to Know (1:08:50)
Low Omega-3 Index and Neurological Problems in Seventh-day Adventist Church Members (1:15:00)
Omega-3 Supplementation vs Fatty Fish: What Does Research Indicate? (1:21:53)
Understanding Essential Fats: Benefits and Sources (1:27:25)
Low Conversion Rates: From ALA to EPA & DHA Explained (1:31:39)
The Importance of Monitoring Omega-6 Intake (1:37:03)
The Link Between Omega-6 Fatty Acids and Inflammation (1:40:55)
Major Omega-6 Food Sources and Healthier Alternatives (1:45:45)
Balancing Omega-3 & Omega-6 to Reduce Inflammation (1:50:25)
The Health Implications of Replacing Saturated Fat with Linoleic Acid (1:53:48)
Polyunsaturated Fats and Cardiometabolic Health (1:58:19)
How Omega-3 & Omega-6 Influence Insulin Resistance and Blood Pressure (2:01:44)
The Long-Term Impact of Consuming Polyunsaturated Fats (2:06:32)
Why You Should Measure Your Omega-3 Levels (2:10:07)
DHA and EPA: Food Sources and Effective Supplementation (2:14:20)
What Forms of DHA and EPA Supplementation Are Most Effective? (2:18:37)
How to Properly Store DHA and EPA Supplements (2:20:27)
Pregnancy and Omega-3s: Essential Benefits (2:21:33)
Supplementing Omega-3s During Pregnancy: Guidelines (2:29:55)
Omega-3 Supplementation Protocol: A Comprehensive Guide (2:38:16)
Outro (2:52:15)
Thank you for tuning in, and for your ongoing commitment to your health. If you found this episode helpful, please share it with someone who could benefit from it.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants -
Episode #330. Uncover the key foundations of a healthy diet and learn how to reduce your risk of chronic disease. What does it take to truly eat well? How do you stay healthy in a food system that prioritises profit? In this episode, originally recorded for Sigma Nutrition Radio, I answer these questions and more.
Learn practical, science-based strategies for building healthier eating habits that can have a lasting impact on your well-being. Tune in to explore topics like nutrition, chronic disease prevention, and how to make informed dietary choices for better long-term health.
Specifically, we discuss:
Introduction (00:00)
Simon’s Background and Journey into Nutrition Science (01:26)
The Importance of Science and Objectivity in Nutrition Advice (08:38)
Barriers to Healthy Eating and Population-Level Solutions (16:06)
Challenges of Adopting Plant-Based Diets and Solutions (30:38)
Omega-3 Fatty Acids: Health Benefits and Plant-Based Sources (38:17)
Conclusion and Final Thoughts on Nutrition and Health (47:21)
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Saknas det avsnitt?
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Episode #329. Boost metabolic health and prevent disease with expert insights from an all-star lineup of scientists. Learn key strategies for improving metabolic health, including metabolic flexibility, muscle health, and the critical roles of diet and exercise in preventing type 2 diabetes and fatty liver disease.
In this episode, you’ll hear from a distinguished panel of specialists including applied exercise physiologist Inigo San Millan, PhD; skeletal muscle expert Don Layman, PhD; type 2 diabetes authority Roy Taylor, PhD; dietitian and researcher Andrea Glenn, PhD, RD; nutrition scientist Alan Flanagan, PhD; nutrition scientist and endocrinologist Christos Mantzoros MD, DSc, PhD; and physician and researcher Richard Johnson, MD.
Specifically, we discuss:
Intro (00:00)
What is Metabolic Health (01:35)
Metabolic Health, Mitochondria, Defining 'Metabolise', Metabolic Flexibility (07:02)
The Importance of Skeletal Muscle for Metabolic Health (20:03)
Exercise for metabolic health ****Zone 2 (28:36)
Twin Cycle Hypothesis (56:45)
Understanding the Personal Fat Threshold (01:08:15)
Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor (01:17:08)
Are DASH, Nordic, Mediterranean, and Portfolio diets good for preventing and managing diabetes? (01:36:46)
Understanding Non-Alcoholic Fatty Liver Disease and Its Development (01:42:39)
The Science of Hepatic Fat Oxidation (01:49:37)
Consequences and Effects of Fatty Liver Disease (01:55:14)
Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (02:00:42)
Combination of Fructose and Saturated fat on Metabolic Health (02:13:21)
Type of fat and its effect on Metabolic Health (02:17:35)
What cause Metabolic Health: fat or fructose (02:24:01)
New Fat Storage Mechanisms - Personal Fat Threshold (02:27:50)
Modern Techniques for Accurate Body Fat Measurement (02:31:52)
Health metabolic biomarkers (02:36:51)
Ectopic fat (02:38:19)
Fat storage and metabolic health (02:39:10)
Evolutionary Insights into Human Fat Storage (02:42:02)
Fatty Liver Disease (02:45:46)
Outro (2:57:46)
Connect with today’s guests and listen to their previous episodes at the links above.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high-protein Plant Performance recipe book -
Episode #328. Are eggs a superfood or a ticking time bomb? The answer is in your genes. Join me to unpack the surprising science of how eggs affect your health depending on your genetic makeup, helping you understand if they’re safe for you.
Discover the two tests you can take to find out if you’re among the 30% of people who are cholesterol hyper-absorbers. You’ll also learn the difference between dietary and blood cholesterol, why cholesterol absorption varies, and what steps to take based on your test results.
Specifically, we discuss:
Introduction: Are Eggs Superfoods or Cholesterol Bombs? (00:00)
Understanding Cholesterol: Dietary vs. Blood Levels (01:25)
The Genetic Factors Influencing Cholesterol Absorption (04:31)
Identifying Cholesterol Hyperabsorbers: Are You One? (09:20)
Testing Methods for Cholesterol Sensitivity (12:41)
Dietary Tips for Cholesterol Hyperabsorbers (13:59)
Key Insights: 5 Critical Facts About Eggs and Heart Health (18:06)
Concluding Thoughts (21:23)
Head to the full show notes for supporting studies and phytosterol testing options.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #327. Butter, bone broth, and eating like our ancestors: join me on The Ellen Fisher Podcast to bust some prolific nutrition myths.
Tune in to unpack my core nutrition philosophy, evaluate how popular diets can impact your health, and examine some key foods that are either idolised as superfoods or condemned as dangerous. If you have questions about keto, carnivore, antinutrients, or other hot nutrition topics, this episode is for you.
Specifically, we discuss:
Introduction (00:00)
Exploring Personal Nutritional Philosophy (02:31)
Science's Role in Nutritional Understanding (06:33)
Integrating Science and Nature in Dietary Patterns (10:55)
Ancestral Diets Explained (14:40)
Saturated Fats and ApoB: Their Crucial Role in Diet (21:03)
Strategies for Reducing Saturated Fat and ApoB Levels (26:49)
Analyzing Evidence Against Saturated Fat Claims (30:16)
Polyunsaturated Fats: Health Impacts Unveiled (40:13)
Processed Foods and Overconsumption Risks (47:33)
Butter and Saturated Fats: Revealing the True Health Effects (49:26)
Comparative Analysis of Various Diets and Health Outcomes (53:30)
Debunking Anti-Nutrient Myths (01:04:36)
Debating Contrasting Nutritional Perspectives with Paul Saladino (01:16:07)
Saturated Fats Comparison: Coconut vs. Red Meat (01:22:26)
The Importance of Personal Health Metrics (01:25:15)
Evaluating Plant Milks and Processed Food Alternatives (01:29:26)
Beef Liver Consumption and Nutrient Toxicity Risks (01:31:15)
Critiquing Vegan Diets and Low-Fat Diet Misconceptions (01:36:54)
Holistic Health and Longevity: Defining the Ultimate Goal (01:45:32)
Conclusion and Key Takeaways (01:48:07)
Discover more of the Ellen Fisher podcast at https://www.ellenfisher.com/podcast, or listen to her previous appearance on The Proof.
Visit the full show notes for more insights and supporting studies.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #326. Could the oils you’re using in the kitchen be increasing your risk of chronic disease? Explore the essential facts about dietary fats and how they affect your health markers in this focused deep dive.
Learn which oils to eat and avoid, how to adjust your diet for optimal intake, and how fats can make the difference between health and chronic disease.
Specifically, I cover:
Introduction to Dietary Fats (00:00)
Types of Fats Explained (02:27)
Essential vs. Non-Essential Fats - What's the Difference? (07:54)
Fats and Cardiovascular Health - Unveiling the Connection (10:32)
How Dietary Fats Influence Blood Pressure (17:47)
The Fat-Inflammation Link (20:29)
Exploring the Relationship Between Fats and Insulin Resistance (26:03)
Long-Term Health Outcomes of Dietary Fat Consumption (29:51)
Optimising Fat Intake: Practical Dietary Recommendations (36:22)
Wrapping up and Final Thoughts (41:25)
Head to the full show notes for additional resources and supporting studies.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #325. Fish oil supplements: harmful or heart-healthy? Learn about the risks and benefits of omega-3 supplementation, including an analysis of a new study that’s been making waves.
Discover how to test your omega-3 levels, how to achieve the optimal index, and my supplement recommendations for a healthy heart and planet.
Specifically, I cover:
Introduction to Omega-3 Fatty Acids and Fish Oil Supplements (00:00)
New Research Reveals Fish Oil's Impact on Cardiovascular Health (01:03)
Challenging Assumptions - A Different Take on the Fish Oil Study Results (05:14)
Dr. Bill Harris Weighs In - Expert Opinions on Omega-3 Benefits (09:03)
How Can I Increase My Omega-3 Levels? Practical Advice for Everyday Life (17:26)
Omega-3 Supplement Strategy (18:50)
Comparing Sustainable Omega-3 Sources: Algae Oil vs. Fish Oil (24:05)
How much omega-3 is too much (25:58)
Does the form of DHA and EPA matter? (28:00)
Does EPA DHA ratio matter? (28:44)
Omega-3 Supplementation for Vegans and Vegetarians (31:50)
Key Takeaways and Recommendations for Omega-3 Supplementation (35:55)
Head to the full show notes for additional insights and supporting resources.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #324. A crash course for carnivores: let’s talk saturated fat, heart disease, and protein as I’m interviewed on Mark Bell’s Power Project.
Do you need to change your diet if you’re feeling good? Can you be overweight and healthy? What simple changes can meat eaters make to improve their long-term health? Hear my answers to these questions and more in this episode.
We cover:
Introduction and Podcast Overview (0:00)
Finding Common Ground in Nutritional Science (02:15)
Genetic Testing and Personalised Nutrition (06:48)
Heart Health Unveiled: The Saturated Fat and ApoB Connection (10:40)
Nutritional Strategies vs Medication for Lowering ApoB (18:39)
Understanding Epidemiology Studies on Red Meat (27:07)
Practical Tips for Transitioning from Animal to Plant Protein (42:05)
A Personal Journey with Nutrition (48:53)
Weight Loss and Metabolic Health Insights (53:41)
Exploring Health Impacts of an All-Meat Diet (01:02:59)
Comparing Plant and Animal Protein Bioavailability (01:12:13)
The Role of Protein in Satiety (01:16:44)
Addressing Seed Oils (01:20:16)
Incorporating Vegetables and Plant Proteins for Optimal Health(01:27:30)
Carnivore Diet vs Plant-Based Diet Discussion (01:33:34)
The Undeniable Importance of Resistance Training (01:39:13)
Ensuring Adequate Intake for Thyroid Health (01:47:23)
Final Thoughts and Farewell (01:50:12)
In this episode, we discuss the importance of getting regular blood tests. Download my free blood test guide to get started.
Connect with Mark Bell, Nsima Inyang, and Andrew Zaragoza on Instagram. If you’re interested in hearing more of Mark Bell’s Power Project, head to https://powerproject.live/.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #323. Oreo cookies or statins – which is more effective in reducing LDL cholesterol? The results from one study might surprise you. Join me as I sit down with Oxford PhD graduate and Harvard Medical student Dr Nick Norwitz to discuss the lipid energy model, what it has to do with Oreos, and how different diets affect your health.
You’ll learn about Dr Norwtiz’s health journey, including his experience with inflammatory bowel disease and the ketogenic diet. We discuss cholesterol management and cardiovascular disease risk, lean mass hyper-responders, and statins. This episode is an important and informative reflection on scientific curiosity and misinformation.
Specifically, we discuss:
Introduction (00:00:00)
The Importance of Curiosity in Scientific Progress (04:39)
Exploring the Oreo vs. Statin Experiment on Lean Mass Hyper Responders (08:52)
Scientific and Clinical Impact of the Oreo Study (25:03)
Addressing Criticisms and Misinterpretations of the Study (34:47)
Navigating Statin Discussions on Social Media (40:27)
Debunking Claims About PCSK9 Inhibitors (53:18)
Challenging Misinformation in Health Communities (59:15)
The Lipid Energy Model and Lean Mass Hyper Responders Explained (01:06:59)
Defining Lean Mass Hyper Responders: Key Terminology (01:14:19)
Practical Advice for Lean Mass Hyper Responders (01:30:35)
The Carnivore Kid: An Intriguing Case Study (01:41:48)
Personal Struggles with Ulcerative Colitis and Starting Keto (01:45:24)
Balancing Medication and Personal Health Choices (01:50:31)
Debating Dietary Interventions for Inflammatory Bowel Disease (02:11:09)
Challenges in Dietary Research and Medical Interventions (02:25:55)
Introducing the Lipid Energy Model and Its Mechanisms (02:34:49)
Debating the Validity of the Lipid Energy Model (02:44:29)
Long-Term Effects of Ketosis and Carb Restriction (02:52:31)
Critiques and Limitations of the Lipid Energy Model (02:57:17)
ApoB-Containing Lipoproteins and Atherosclerosis (03:03:50)
Current Research and Future Directions on LMHR (03:06:41)
Exploring Inflammatory Responses to Fibre (03:16:12)
The Link Between Saturated Fats and Heart Disease (03:20:49)
Closing Thoughts on Effective Scientific Communication (03:25:29)
The Lean Mass Hyper Responders Debate: Addressing Frustrations (03:32:32)
Understanding Carbohydrate Reintroduction Physiology (03:46:58)
Diet-Specific Strategies to Lower ApoB (03:55:16)
Examining Claims About ApoB and Cardiovascular Disease (04:01:50)
Trade-offs in Lowering ApoB Levels (04:12:54)
Exploring the Link Between All-Cause Mortality and ApoB (04:22:42)
Lean Mass Hyper Responders and ApoB: A Unique Profile (04:44:54)
Concluding Thoughts and Future Discussion Topics (04:48:10)
Connect with Nick Norwitz, PhD on Twitter/X, Instagram, and YouTube. Make sure to check out the full show notes for additional resources and supporting studies.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill -
Episode #322. Did you know that 30% of cancers are related to obesity? Join me as I sit down with Harvard Professor and endocrinologist Dr Christos Mantzoroz to discuss fatty liver disease, metabolic health, and hormones.
You’ll learn about why so many people are obese and whether you can be overweight and healthy. Dr Mantzoroz breaks down budget-friendly ways to evaluate your metabolic health, explains how hormones affect your weight, and offers his insight on how to treat obesity. Overall, this episode is a masterclass in metabolic health and fatty liver disease.
Specifically, we discuss:
Introduction to The Latest Obesity Research Findings (00:00)
The Evolving Understanding of Obesity Science (03:49)
Uncovering New Fat Storage Mechanisms (10:57)
Modern Techniques for Accurate Body Fat Measurement (15:02)
Why Maintaining Weight Loss Is So Challenging (20:01)
Evolutionary Insights into Human Fat Storage (25:12)
How Leptin Regulates Energy Balance and Health (29:17)
New Approaches to Break Through Weight Set Points (39:27)
Environment's Role in Weight Gain Beyond Diet (45:49)
Decoding the Genetics of Fat Storage and Metabolism (52:59)
Non-Alcoholic Fatty Liver Disease Explained (55:40)
Evidence-Based Nutrition for Optimal Liver Health (01:05:25)
Promising Advances in Non-Invasive Liver Tests (01:10:49)
Oestrogen's Impact on Metabolism (01:20:14)
The Link Between Liver Fat and Insulin Resistance (01:22:04)
Addressing America's Growing Metabolic Health Crisis (01:26:11)
Outro (01:27:11)
Connect with Christos Mantzoros, MD DSc PhD h.c. mult. on LinkedIn, and discover his work here.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #321. You’ve heard me interview hundreds of nutrition experts; now it’s time for me to share my comprehensive views on nutrition, health, and longevity. Join me as I’m interviewed by André Duqum in this conversation originally recorded for the Know Thyself podcast.
This episode covers the foundations of healthy eating and my take on common nutrition controversies. You’ll learn how to decode health information you find online, why a plant-focused diet is the best way forward, and how to discover the optimal diet for you. Overall, we discuss what to eat and avoid, when to eat, and how your food choices impact your body and the planet.
Specifically, we discuss:
Understanding Nutrition Science (04:07)
The Role of Observational Studies in Nutrition (09:18)
What Is the Most Beneficial Diet for Humans? (13:12)
Simon Hill's Personal Journey and Motivation (19:38)
Five Pillars of Longevity (27:50)
Importance of Protein in the Diet (31:27)
Understanding Seed Oils and Polyunsaturated Fats (50:23)
Importance of Fibre in the Diet (58:32)
Choosing the Best Animal Proteins (01:10:06)
Role of Fake Meats in a Plant-Based Diet (01:14:52)
Metabolic Health and Dietary Fats (01:19:40)
Supplementation and Nutrient Gaps (01:24:22)
Debunking Myths About Anti-Nutrients in Plants (01:30:20)
The Soy Controversy Explained (01:38:20)
Challenges of Plant-Based Diets (01:41:29)
Environmental Impact of Diet Choices (01:59:04)
Optimising Meal Timing (02:07:07)
Importance of Relationships for Longevity (02:12:52)
Connect with André Duqum on Instagram, and discover the Know Thyself podcast on Instagram or at the official website, https://www.knowthyself.one/.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
LMNT
Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #320. Are you part of the 20% of people with this dangerous gene? There’s a cheap, simple test you can do just once in your life to find out. Join me as I sit down with renowned lipidologist Dr Thomas Dayspring to help you understand Lipoprotein(a) and the test that might change your life.
In this episode, you’ll learn what Lp(a) is and how it can affect your cardiovascular disease risk through two key pathways. Dr Dayspring unpacks why it’s so important to test, how to ask for this test, and what to do with your results.
Specifically, we discuss:
Introduction (00:00)
Demystifying Lipoprotein(a): An Overview of its Role in Cardiovascular Health (02:54)
Genetic Inheritance Patterns and Variability of Lipoprotein(a) (10:11)
Drug Development Strategies for Reducing Lipoprotein(a) Levels (14:50)
Exploring the Functional Role and Genetic Variations of Lipoprotein(a) (20:27)
Inside the Artery Walls: Mechanisms and Structure of Lipoprotein(a) (32:34)
A Deep Dive in Production to Measurement of Lipoprotein(a) (42:32)
Identifying High-Risk Indicators for Lipoprotein(a) (58:54)
Statins and Elevated Lipoprotein(a): Understanding the Relationship (01:11:42)
Exploring PCSK9 Inhibitors in Lipoprotein(a) Management (01:20:30)
Emerging Treatments and Future Therapies for Lowering Lipoprotein(a) (01:31:22)
Exploring Lifestyle Considerations and Alternative Therapies (01:34:42)
Oxidized Phospholipids and Their Role in Cardiovascular Health (01:43:15)
Relationship Between Oxidized Phospholipids and Lipoprotein(a) (01:52:00)
Understanding Aortic Valve Calcification and Its Link to Lipoprotein(a) (01:59:40)
Key Takeaways and Future Landscape of Lipoprotein(a) Treatments (02:06:52)
Conclusion and Final Remarks (02:13:30)
Connect with Dr Thomas Dayspring on Twitter/X. Listen to our previous lipid series and download the cheat sheet here.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #319. Join me today as I sit down with a very special guest: my dad, Professor Michael Hill, PhD. Dad’s journey as a scientist has inspired my own work and taken our family across the globe, and I’m honoured to host him as he shares his story from early career discoveries to current research.
As well as getting an inside look at Dr Hill’s academic career, you’ll learn about microvasculature (very small blood vessels), including what they are and how they impact human health. Dad also shares his experience with a heart attack, offers advice on preventing atherosclerosis, and weighs in on the Ozempic and vaping conversations.
Specifically, we discuss:
Introduction (00:00)
Childhood Memories and Early Interests (03:19)
Pursuing a Career in Biochemistry (08:36)
Microvasculature and Diabetes Research (12:12)
Early Research on Investigating Blood Properties and Diabetes (17:44)
Family Stories and Moving to the U.S. (28:47)
Returning to Australia and Continued Research (36:39)
Exploring Microvessel Behaviours: Research at RMIT (41:34)
Dealing with Health Challenges and Maintaining Work-Life Balance (46:20)
Understanding Microvascular Functions and Cardiac Health (50:32)
Exploring Vessel Constriction and Small Blockages: A Closer Look (01:00:15)
Understanding the Impact of Large Arterial Stiffness on Vascular Health (01:07:01)
Identifying Risk Factors: A Comprehensive Approach to Vascular Well-being (01:11:01)
Personal Views on the Evolution of Scientific Research Access (01:19:39)
Returning to the USA: Advancing Research on Blood Vessel Mechanisms (01:21:58)
COVID-19 and Metabolic Syndromes: Exploring the Early Research Connections (01:27:30)
Current Research and Future Directions (01:29:29)
Reflecting on a Career Dedicated to Science: Family, Achievements, and Future Directions (01:34:48)
If you’re interested in learning more about Dad’s work and career, head to his profile here.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants -
Episode #318. 50,000 women. 30 years of follow-up. The results of a new study are in: learn the truth about how your protein intake will affect your long-term health. What kind of protein should you consume? How much? And what difference will it really make on longevity?
Today, I’m unpacking the results from the new study in the American Journal of Clinical Nutrition, “Dietary protein intake in midlife in relation to healthy aging - results from prospective Nurses' Health Study cohort”.
This new study from researchers at Harvard University and Tufts University has been regularly misinterpreted online, and in this episode, I’ll set the facts straight. Learn the three most important protein takeaways from this study, hear my take on Layne Norton’s interpretation, and crack the code to using protein as a tool for healthy aging.
Specifically, I cover:
Introduction to Protein and Longevity (00:00)
Study Overview and Methodology (01:24)
Key Findings on Protein Sources (05:33)
Lane Norton's Review and Critique (06:38)
Analysis of Different Protein Types (10:02)
Practical Recommendations for Protein Intake (17:13)
Conclusion and Final Thoughts (21:34)
If you’re interested in the Danish Dietary Guidelines, you can find them in English here.
This episode is brought to you by:
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com.
WHOOP
Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #317. Are you neglecting your social health without realising it? We know connection is the often-forgotten pillar of wellbeing and longevity – but how much of a difference does it truly make to your physical and mental health? More than you might think. Join me as I sit down with Kasley Killam, a leading expert in social health, to discover the science behind why relationships are so critical to our well-being.
In this episode, Kasley Killam paints a comprehensive picture of the importance of social health and how you can foster it. You’ll learn how connection affects physical and mental health, what good social health is, and how to achieve it. We also discuss what to do about difficult relationships, how to build a strong relationship with yourself, and how to fit intentional connection into a busy schedule.
Specifically, we discuss:
Introduction to Kasley Killam and Her New Book (00:00)
What is Social Health? (03:11)
The Importance of Social Health (06:17)
Mechanisms Linking Social Health and Physical Health (11:04)
Practical Tips to Boost Your Social Health (16:48)
Overcoming Challenges & Misconceptions About Social Health (20:44)
Personal Practices and Experiments (22:29)
Building and Assessing Social Health (34:32)
The Decline of Friendships and Social Health (44:32)
Impact of Technology on Social Connections (47:10)
Work Trends and Social Health (49:11)
Public Health and Social Health Innovations (50:12)
Fostering Social Health in the Corporate World (54:11)
Decode Your Social Health Style (01:00:37)
Self-Compassion and Building a Relationship with Yourself (01:15:04)
Envisioning a Socially Healthy Future (01:22:08)
Conclusion and Final Thoughts (01:23:37)
Head to https://www.kasleykillam.com/ to learn more about Kasley Killam’s work and purchase her new book, The Art and Science of Connection. Connect with her on Instagram, Twitter/X, and LinkedIn, and subscribe to her newsletter here.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
Eimele
Use code SIMON at checkout for 10% off your first order.
38TERA
Use code THEPROOF for a discount at checkout.
WHOOP
Claim your first month free on join.whoop.com/simon.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants -
Episode #316. Overeating is not your fault. But it is in your control – just not in the way you might think. Learn how to overcome food addiction in this conversation with psychiatrist, neuroscientist, and self-mastery expert, Dr Jud Brewer.
Learn Dr Brewer’s secret to gaining control over your eating habits (and no, it’s not willpower). Discover why we overeat, the reason you can’t break bad habits, and how to take back your power over food as we unpack the science of behavioural change.
Specifically, we discuss:
Introduction: Understanding the Brain and Habit Formation (00:13)
Key Elements of Habit Formation (02:55)
The Brain's Role in Decision-Making and Habit Change (10:02)
The Impact of Awareness and Mindfulness on Habit Change (14:58)
Analysing Eating Habits and the Food Environment (24:35)
Survivorship Bias in Successful Habit Change (27:36)
Emotional Eating and Coping Mechanisms (31:17)
Addressing Guilt, Shame, and Systemic Failures (36:24)
Environmental Influences on Eating Patterns (41:18)
Breaking Negative Eating Habits: Weight Loss Journey (49:00)
Effective Strategies to Stop Destructive Habits: Breathwork (58:53)
The Role of Psychedelics and Meditation in Overcoming Negative Eating Habits (1:01:24)
How the Brain Changes When We Modify Eating Habits (1:04:36)
Pharmacology vs. Mindfulness: Which Is More Effective? (1:07:57)
Practical Tips to Overcome Night Cravings (1:19:10)
Measuring Success in Habit Change (1:28:50)
Debunking the 21-Day Habit Formation Myth (1:34:51)
Conclusion and Final Thoughts (1:35:54)
Connect with Dr Jud Brewer on Instagram, Twitter/X, YouTube, and Threads. Learn more about Dr Brewer on his website, https://drjud.com/, where you can also order his latest book, The Hunger Habit.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon.
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com
Cozy Earth
Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at cozyearth.com for up to 35% off.
Eimele
Use code SIMON at checkout for 10% off your first order.
38TERA
Use code THEPROOF for a discount at checkout.
WHOOP
Claim your first month free on join.whoop.com/simon.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book -
Episode #315. What is ApoB and why should you care? In this latest instalment of our masterclass series, I’ve distilled the essential insights about apolipoprotein B (ApoB) into one informative episode. Join top experts including Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho as they unravel the significance of ApoB as a crucial marker of cardiovascular health. This episode provides a thorough understanding of why ApoB matters and how it impacts your health.
We unpack the essentials of ApoB, covering its role in cholesterol transport and why it's a key marker for heart disease risk. You'll learn how ApoB affects cardiovascular health, from the way it modifies LDL particles to its impact on atherosclerosis and longevity. We discuss the best ways to measure ApoB, its normal levels, and what causes it to rise. The episode also explores the relationship between ApoB and saturated fats, and why it's a more reliable risk marker than LDL cholesterol. By the end, you'll have a clear understanding of why ApoB matters for your heart health and how it can help guide better health choices.
Specifically, we discuss:
Introduction (00:00)
Lipoproteins & Cholesterol: Transport and Recycling (00:43)
Cholesterol's Role in Lipoproteins (26:40)
Is ApoB a More Accurate Marker of Cardiovascular Risk? (31:13)
Endothelial Transcytosis of Lipoproteins (39:42)
LDL Modification and Aggregation (49:17)
Evidence for ApoB's Role in Atherosclerosis (55:49)
ApoB and Genetics (58:29)
ApoB and Longevity (1:02:16)
Mechanisms Behind Elevated ApoB Levels (1:05:14)
Why ApoB is the Best Predictor of Cardiovascular Disease (1:08:52)
ApoB vs LDL-Cholesterol: Understanding the Discordance (1:21:00)
Healthy ApoB Levels for Young Adults (1:31:39)
Causes of Elevated ApoB Levels (1:45:16)
Target ApoB Levels for Cardiovascular Disease Prevention (2:04:31)
The History and Evolution of the Lipid Hypothesis (2:07:27)
Role of ApoB Lipoproteins in Atherosclerosis (2:10:21)
Importance of ApoB as a Cardiovascular Risk Marker and Its Clinical Application (2:18:39)
Impact of Saturated Fat on ApoB and Cardiovascular Disease (2:27:47)
Top Saturated Fat Foods That Increase Cardiovascular Risk (2:33:53)
Impact of Saturated Fat on ApoB and Cardiovascular Disease (2:35:49)
Dietary Changes to Lower ApoB Levels (2:38:59)
Outro (2:45:54)
Read more about the guests featured on this episode or connect with them on their respective pages on The Proof website: Dr Thomas Dayspring, Dr William Cromwell, Danny Lennon, Dr Alan Flanagan, and Dr Gil Carvalho.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Shopify
Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants -
Episode #314. Science tells us we need relationships to live better, for longer. But how do we cultivate our relationships to benefit ourselves and our loved ones? Join me in Episode #314 as I sit down with IN-Q for an exploration of creativity, self-compassion, and empathy.
In this episode, you’ll discover why you should learn to be vulnerable and how to do so. We discuss the danger of loneliness and how to improve life satisfaction, why creativity is a crucial practice for everyone, and how you can truly learn from failure. IN-Q also shares some of his poetry as well as key moments in his journey to where he is today.
Specifically, we discuss::
Introduction (0:00)
IN-Q Performs His Poem “Growth AKA Goldfish” (1:32)
The Importance of Emotional Health and Vulnerability (5:48)
Does Expressing Emotions Show Weakness? (12:34)
The Creative Process and Overcoming Failure (19:06)
From Poetry to Platinum Hits: A Diverse Creative Journey (29:19)
The Intention Behind Poetry and Empowering Through Creativity (34:40)
The Creative Process: Inspiration, Writing, and Reflection (41:57)
Finding Play and Presence in Life (47:04)
A Poet's Journey: From Personal Struggles to Creative Expression (50:58)
Love, Relationships, and the Quest for Connection (1:01:09)
Launching "The Never-Ending Now" Poetry Journal and Album (1:12:46)
Closing with Empowerment: A Poem of Pride (1:14:06)
Outro (1:18:35)
Connect with IN-Q on Instagram. His website, in-q.com, is your go-to to learn more, listen to The Never Ending Now album, shop his journal and book, and more.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon.
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants -
Episode #313. Is your menstrual cycle normal? How is the pill affecting your body? Join me as I sit down with Dr Jen Gunter, a renowned expert in women's health, to answer these questions and many more as we take a deep dive into contraception, the menstrual cycle, and common female health myths.
You’ll learn about the key phases of the menstrual cycle and the associated symptoms, discover how different forms of hormonal contraception work and whether they’re safe, debunk a series of pervasive female health myths, and much more. Whether you personally menstruate or use contraceptives or know someone who does – effectively everyone – this episode is an essential listen on female health.
Specifically, we discuss:
Intro (00:00)
The Impact of Disinformation on Women's Health Choices (01:17)
Exploring Gaps in Medical Research on Female Physiology (07:17)
Navigating Misinformation and Vulnerability in Women's Health (15:52)
The Importance of the Menstrual Cycle: A Comprehensive Overview (17:44)
Inclusivity and Language in Medical and Social Contexts (33:12)
The Phases of the Menstrual Cycle: A Detailed Explanation (41:02)
Female Physiology: Mechanism and Function of Menstruation (50:25)
COVID Vaccines: Effects on Menstrual Cycles and Fertility (01:01:55)
Menstrual Myths Debunked: Separating Fact from Fiction (01:06:00)
Managing Menstrual Symptoms and Pain: Expert Advice (01:13:45)
Hormonal Health Myths: Dutch Test, Birth Control Pill, and Diet (01:39:33)
Osteoporosis and Birth Control Pills: Is There a Connection? (01:46:26)
Birth Control and Cancer Risk: Examining the Evidence (01:51:25)
Birth Control Pills and Acne (01:57:30)
Menstrual Cycle: Detoxification and Birth Control's Impact on Maturation (02:02:03)
Emergency Contraception Options: Plan B and Ella (02:08:48)
Abortion: Laws, Misconceptions, and Future Implications (02:30:03)
Final Thoughts and Empowering Women in Health Choices (02:45:56)
Connect with Dr Jen Gunter on Instagram, Twitter, and TikTok. Order her new book, Blood: the Science, Medicine and Mythology of Menstruation, here. For even more comprehensive information, you can read Dr Gunter’s other books, The Vagina Bible and The Menopause Manifesto. Head to her blog, https://vajenda.substack.com/, for frequent newsletters and articles.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Head to insidetracker.com/simon and get 10% off the InsideTracker subscription and any plan.
BON CHARGE
Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at boncharge.com and use code THEPROOF for a 15% discount.
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
Want to support the show?
The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Watch the episodes on YouTube or listen on Apple/Spotify -
Episode #312. Vegan vs. omnivore: learn about the Netflix documentary “You Are What You Eat” and the associated twin study with lead researcher, Christopher Gardner PhD. You’ll learn about why Dr Gardner designed the study the way he did, unpack some key findings, and hear his response to criticisms.
From publication, this study gained major media attention that was only amplified by the release of “You Are What You Eat”. With popularity comes criticism, in this case from some big names in online nutrition spaces. Hear the truth about the controversy surrounding this study and documentary, straight from the source.
Specifically, we discuss:
Intro (00:00)
Introduction and background on Christopher Gardner's recent twin study (01:36)
Navigating the Challenges of Science Communication and Critique (08:28)
Introduction to the Twin Study and Its Unique Design (16:36)
The Role of Identical Twins and Defining Plant-Based vs. Omnivorous Diets (22:45)
Dietary Patterns and Health Outcomes: The Vegan and Omnivorous Diets (27:25)
Diet Satisfaction and Adherence in Nutritional Studies (36:34)
The Science of Study Design: Primary vs. Secondary Outcomes (42:05)
Responding to critiques on calorie differences (51:58)
Cardiometabolic Markers and Diet: A Deep Dive (55:17)
Twin Nutrition Study Deep Dive: Lipid Markers, Cardiovascular Risk, and the Impact of Diet (01:00:13)
Responding to Critiques (Peter Attia): The Complexity of Diet Studies (01:14:07)
Addressing Critique of Mark Hyman (01:29:24)
Funding from Beyond Meat and other organisations (01:38:55)
Teaching about sustainability and stealth nutrition - Nina Teicholz critique (01:44:29)
Is Plant-Based Diet good for the environmental health? (01:48:00)
Reflecting on critiques and potential improvements to the study (01:53:47)
Personal experience with the Netflix documentary (01:55:45)
Outro (01:57:54)
Connect with Professor Christopher Gardner on Twitter/X and Instagram. Head to https://nutrition.stanford.edu/ for more resources and studies, and the Stanford Nutrition YouTube channel for more videos. Listen to past episodes featuring Professor Gardner here.
This episode is brought to you by:
InsideTracker
If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon.
Sun Home Saunas
Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
Momentous
My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com
Eimele
Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order.
38TERA
Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.
Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
Author of The Proof is in the Plants
Watch the episodes on YouTube or listen on Apple/Spotify
Connect with me on Instagram, Twitter, and Facebook
Nourish your gut with my Plant-Based Ferments Guide
Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book - Visa fler
