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  • I am honored to connect with Esther Blum today! She is the bestselling author of "Cavewomen Don’t Get Fat," "Eat, Drink, and Be Gorgeous," and most recently, "See Ya Later, Ovulator!". Esther currently maintains a busy virtual practice where she helps women balance hormones, lose stubborn body fat, and treat the root cause of health struggles. 
    Today we speak about medical gaslighting, how weight gain does not have to be a part of aging, andropause and menopause, and the Women’s Health Initiative. We dive into physical changes and significant symptoms during perimenopause and menopause, the role of the pelvic floor, deciphering what the dreaded “menopot” is, what does not work, and advocacy in terms of testing and hormones. We also address constipation, weight loss resistance, and how our tolerance for alcohol changes as we age, especially when using bioidenticals or hormone replacement therapy. 
    IN THIS EPISODE YOU WILL LEARN:

    How women can redefine their experience and continue having an active sex life after menopause.

    How to surrender, lean in, and take the pressure off yourself while going through perimenopause and menopause.

    Why is there so much misinformation and medical gaslighting in our society?

    Why Esther wrote See Ya Later, Ovulator!

    Some common symptoms of perimenopause.

    Risks women may face after a hysterectomy.

    Changes that happen in the vaginal canal and pelvic floor during menopause.

    The significant and profound impact of the decline of sex hormones.

    How to avoid weight gain in menopause.

    What can menopausal women do to prevent fatty liver and digestive problems?

    Lab tests women should be asking their health providers for.

    Why should perimenopausal women avoid alcohol? 

    Some simple ways to address constipation.


    Connect with Cynthia Thurlow
    Follow on Twitter, Instagram & LinkedIn
    Check out Cynthia’s website

    Connect with Esther Blum
    On her website
    On Facebook, Instagram, LinkedIn
    Get your free copy of Esther’s Happy Hormone Cocktail

    Esther’s Books
    Esther’s book, See Ya Later, Ovulator!, by Esther Blum
    Cavewomen Don’t Get Fat, by Esther Blum
    Eat, Drink, and Be Happy, by Esther Blum

  • Today, I am honored to connect with Dr. Sean O'Mara, the leading global health and performance-optimizing physician. 
    Dr. O'Mara is a former ER physician and attorney. He works with business executives, professional performers, and athletes, and he has also had the chance to collaborate with multiple United States presidents, Secretaries of State, senior government officials, and high-level foreign dignitaries. 
    In our discussion today, we address the dangers of visceral fat and the general lack of awareness of it, particularly among healthcare professionals. We cover various types of fat, the influence of Big Pharma, and the impact of menopause on disease susceptibility. We dive into health optimization, sarcopenia, sarcopenic obesity, frailty, adiponectin, and MRIs for assessing visceral fat, and Dr. O'Mara offers valuable insights on muscle tissue differences, lifestyle factors, epigenetics, and the most effective exercises, discussing his advocacy for intermittent fasting, the importance of clinical labs, and the specific supplements for managing visceral fat. He also shares his thoughts on alcohol and caffeine. 
    This engaging and informative episode with Dr. Sean O’Mara features numerous slides and MRI images. So, I recommended viewing it on YouTube.

    IN THIS EPISODE YOU WILL LEARN:

    Why visceral fat is a significant contributor to chronic disease

    How visceral fat invades muscles, leading to the loss of spinal erectness

    Why superficial subcutaneous fat is essential for health

    The impact of visceral fat on muscle mass and bone density in older adults

    How lifestyle choices impact metabolic health

    The benefits of fermented foods and extended fasting for optimal health

    Why Dr. O’Mara believes that modern humans are less intelligent than our ancestors

    How fasting helps to cleanse the body and reverse disease

    How distance running and cycling can impact the body negatively, and the benefits of sprinting

    Why Dr O’Mara recommends avoiding alcohol



    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Sean O'Mara

    On his website


    Instagram

    YouTube

    TikTok

    LinkedIn

    Join Dr. O’Mara’s online community (www.drseanomara.podia.com) 


    Recommended Podcast
    What Alcohol Does to Your Body, Brain & Health, from Andrew Huberman

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  • I am delighted to have Shawn Wells, affectionately known as the Ingredientologist, joining me again today. Shawn is a leading nutritional biochemist and health optimization expert. He is also a biohacker and the formulator of over 500 supplements, foods, beverages, and cosmeceuticals. 
    In our conversation today, we cover how to evaluate the quality of supplements, explain what proprietary blends represent, and explore several exciting new supplements like Peptide 185, Paraxanthine, and various nootropic agents. Shawn shares his optimal supplement stacks for sleep, metabolism, gut health, and regulating blood sugar, diving into the impact of delivery systems, including transdermal approaches and IV therapies. He also offers guidance on setting intentions and affirmations around supplement consumption. 
    I trust that you will find this conversation with Shawn Wells as enjoyable and informative as I did while recording it.

    IN THIS EPISODE YOU WILL LEARN:

    Shawn shares his concerns about quality control in supplement manufacturing.

    Why it is essential to buy supplements only from trusted brands when ordering from big retailers

    Shawn discusses the potential benefits of the new supplement, Peptide 185, for muscle protein synthesis.

    The potential leucine holds for age-related muscle loss and sports nutrition. 

    Shawn dives into the physical effects of the caffeine metabolite paraxanthine.

    BDNF-boosting ingredients for neuroplasticity and brain protection

    How adaptogenic herbs can increase resilience and improve sleep quality, energy, and focus

    Shawn highlights the importance of physical movement and proper posture for maintaining physical health.

    How a leaky gut can lead to immunological problems and cognitive impairment

    Shawn explores the effectiveness of supplementation versus methods like high-intensity interval training for boosting NAD levels.

    Shawn explains how to use intention and affirmations to maximize the absorption of supplements.


    Bio: Shawn Wells:
    Shawn Wells MPH, LDN, RD, CISSN, FISSN is the world’s leading nutritional biochemist and expert on health optimization.
    Meet the Ingredientologist, a visionary scientist behind over 1000 groundbreaking formulations, including 25 patented ingredients like Paraxanthine, Teacrine, Dynamine, and Dihydroberberine. Once a Chief Clinical Dietitian, he has empowered thousands with innovative health solutions like keto, paleo, fasting, and supplements, overcoming his own battles with Epstein-Barr Virus, Chronic Fatigue Syndrome, and more.
    As a world-renowned thought leader on mitochondrial health, he has spoken on five continents and featured in acclaimed documentaries and podcasts. Discover his practical, research-backed solutions in "The ENERGY Formula," hailed by USA Today, Forbes, and an Amazon best-seller. Experience greater resilience and boundless energy under his expert guidance.
    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Shawn Wells

    On his website 

    Shawn’s biohacking book, The Energy Formula


    On Instagram, YouTube, Facebook, LinkedIn, Twitter, Pinterest, and TikTok 


    Previous Episode Mentioned
    Ep. 126 – Plant Medicine: Bio-Hacking Your Way to Optimum Health featuring Shawn Wells

  • I am thrilled to have Gary Taubes back on the show today. (He was with me before on episode 137. Gary is an investigative science and health journalist whose work has been pivotal in catalyzing the low-carb keto movement. He has written many books, including his most recent, Rethinking Diabetes, and his articles are in many of the best anthologies. He has also received many science awards.
    Today's discussion is particularly significant, given the recent report from the American Diabetes Association revealing that the annual cost of diabetes in the United States reached a staggering $412.9 billion in 2022, with individuals diagnosed with diabetes now representing one in every four dollars spent on healthcare. 
    In our discussion today, we dive into the history of diabetes, pertinent statistics, the prevailing standard of care, and the transformative influence of insulin on diabetes management and reactive hypoglycemia. Gary provides insights into his reactions to GLP ones, the integration of medical and nutrition science into the medical field, and the influence of organizations such as the American Diabetes Association, AHA, USDA, and NIH. Our discussion also extends to the effects of pharmaceuticals, the shortcomings in our approach to diabetes management and existing models, and the challenge the low-carb community faces.
    Stay tuned for today's eye-opening conversation, where we shed light on the complexities surrounding diabetes care, explaining how simple lifestyle changes can tremendously improve quality of life.

    IN THIS EPISODE YOU WILL LEARN:


    Rethinking Diabetes is a groundbreaking exploration of diabetes diagnosis, management, and treatment

    Gary discusses the evolution of evidence-based medicine

    Why the traditional medical approach to treating diabetes is inadequate

    How the guidelines of the American Diabetes Association were based on outdated assumptions 

    How medical treatments compare with lifestyle changes for managing diabetes

    Controversies surrounding how the pharmaceutical industry has influenced the way medical associations have shaped their diabetes management policies

    How medical guidelines and dietary advice have evolved

    What constitutes a healthy diet?

    How patients often have trouble following diet recommendations, despite their best intentions

    Is obesity a hormonal disorder or caused by overeating?

     
    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Gary Taubes

    On his website


    Twitter

    Facebook


    Previous Episode Mentioned:
    Ep. 137 – High Blood Sugar Levels And Its Long-Term Damage with Gary Taubes

    Book Mentioned:
    Rethinking Diabetes What Science Reveals About Diet, Insulin, and Successful Treatments
    is available from most bookstores or on Amazon.

  • Today, I am thrilled to reconnect with one of my favorite physicians, Dr. Lara Briden, a naturopathic doctor specializing in women's health. 
    Dr. Briden is on a mission to help women achieve natural menstrual cycles without relying on hormonal birth control. She has authored several books, including her latest, Metabolism Repair for Women.
    In our conversation today, we dive into why we cannot consciously control energy balance, the impact of ultra-processed foods, epigenetic factors in obesity, the significance of satiety hormones, the role of muscle, and the effects of visceral fat versus subcutaneous fat. We also discuss ways to assess metabolic health and explore various treatments. 
    This insightful discussion with Dr. Lara Briden is bound to captivate and inform all our listeners. Stay tuned for more.

    IN THIS EPISODE YOU WILL LEARN:

    Why energy balance is not under our conscious control

    How the regulatory mechanism in the body naturally reduces hunger and burns energy

    How ultra-processed foods were created to be addictive and lead to overeating

    How the adiponectin hormone impacts insulin sensitivity and satiety

    The importance of maintaining muscle mass and avoiding sarcopenia, particularly during menopause

    The difference between subcutaneous and visceral fat

    Measuring and managing visceral fat

    How High triglycerides often indicate insulin resistance

    The limitations of the fasting insulin test

    Using the entrainment of circadian rhythm to improve metabolic health

    The benefits of addressing gut problems for improving metabolic health


    Connect with Cynthia Thurlow  

    Follow on Twitter


    Instagram

    LinkedIn

    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Lara Briden

    On her website


    On social media: @Lara Briden 


    Dr. Briden’s latest book is titled The Metabolism Reset in Australia and New Zealand. Everywhere else, it is titled Metabolism Repair for Women

    Other Books by Dr. Briden
    Period Repair Manual
    Hormone Repair Manual

    Previous Episode Mentioned
    Ep. 220: A Detailed Guide to Healthy Hormones with Dr. Lara Briden

  • I am sincerely honored to connect with Walter Green today. 
    Walter served as the Board Chairman and CEO of Harrison Conference Services for 25 years and played a significant role in the Young Presidents Organisation. Since selling his company, he has dedicated himself to supporting various nonprofits, focusing on education and health for the underserved. 
    Walter’s work is powerfully inspiring. I initially heard him on one of Peter Attia’s podcasts, which moved me so profoundly that I shared it with anyone willing to listen. In our conversation today, Walter shares his background and we discuss how I took purposeful action after hearing him talk on the podcast. We dive into gender socialization and emotional expression, the value of authenticity and integrity, the concept of saying it now, and the importance of intentionality and boundaries. We also discuss crucial elements of making meaningful connections, cultivating deep, authentic friendships, and transforming our lives to become agents of change. 
    Having this conversation with Walter was invaluable for me, and I have no doubt you will also love it.

    IN THIS EPISODE YOU WILL LEARN:

    Reflecting on his 60 years of marriage, Walter highlights the importance of deep passion and respect in enduring relationships.

    Walter offers his perspective on authenticity and openness in relationships, emphasizing the importance of being true to yourself.

    How Walter values authenticity in his relationships and finds it hard to be open and vulnerable with those who are not candid and authentic  

    How Walter’s career in finance influenced his relationships

    Walter talks about gratitude and shares how at the age of 71, he shared stories with people he loved on Zoom, inspiring the Say It Now movement.

    Walter shares his journey of intentional living, explaining the importance of thinking backward and aligning your actions with your ideal outcomes.

    Why it is essential to consider the context of every decision you make in all aspects of life

    The importance of finding your purpose and living in the present  

    The benefits of developing deep and long-lasting relationships

    How to identify those who have made a difference in your life

    Walter discusses love languages, sharing the importance of understanding how others prefer to receive love and affection.


    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Walter Green

    On Just Say It Now website


    On This Is the Moment website (For Walter’s book)

    Walter’s Ted Talk: Why We Should Eulogize the Living


    Peter Attia’s Podcast: The impact of gratitude, serving others, embracing mortality, and living intentionally with Walter Green

  • I’m honored to reconnect with Dr. Felice Gersh today! She is a multi-award-winning physician with dual board certification in OB-GYN and Integrative Medicine. We connected once before in Episode 221, where we spoke about PCOS and metabolic health.
    Today, Dr. Gersh joins me to dive into perimenopause and menopause. We discuss various issues surrounding the Women’s Health Initiative, and talk about estrogen as a family of hormones, estrogen-mimicking chemicals, synthetic hormones, and oral contraceptives. We get into the importance of thyroid function, the pro-inflammatory state of a loss of estrogen in perimenopause and menopause, and the importance of nutrition and exercise for the metabolism. We also speak about the lesser-known changes that occur in menopause, including changes in body odor, constipation, sarcopenia, osteoporosis, and vocal changes. 
    I intend to invite Dr. Gersh back to discuss women and mitochondrial health and to talk about her latest book, Menopause: The Fifty Things You Need to Know. 
    Stay tuned to find out what menopause really is and what it does to a woman’s metabolic system.

    IN THIS EPISODE YOU WILL LEARN:

    Dr. Gersh discusses the Women’s Health Initiative study and its devastating effects.

    The difference between synthetic and bioidentical hormones.

    How chronic diseases of aging can be delayed when hormones are incorporated along with other lifestyle refinements.

    What do hormones do?

    Why every immune cell in the body has receptors for vital hormones.

    Why menopause cannot be defined by a specific moment in time.

    Changes that occur physiologically during the perimenopause years.

    How hormones can change the perimenopause paradigm entirely.

    Why perimenopause translates into many sleep issues.

    Why phytoestrogens are nature’s gift to women.


    Connect with Cynthia Thurlow

    Follow on Twitter


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    LinkedIn

    Check out Cynthia’s website 


    Connect with Dr. Felice Gersh

    On her website: Integrative Medical Group of Irvine


    On Instagram



    All of Dr. Gersh’s books are available on Amazon
    Episode 221 on PCOS with Dr. Felice Gersh

    Resource Mentioned
    Go to www.toxicology.gov to see all the ingredients in birth control pills listed as endocrine disruptors.

  • Today, I am delighted to connect with my dear friend, Dr. Mariza Snyder. Dr. Snyder is a best-selling author, dedicated wife, and wellness advocate passionately committed to empowering women through lifestyle changes, whole food nutrition, essential oils, and other health practices. 
    In our discussion today, we dive into the perimenopausal journey, looking at the warning signs and ways to rediscover ourselves. We explore the impact of lifestyle choices and the importance of understanding cravings in middle age, offering practical strategies for navigating perimenopause and menopause. We get into the benefits of continuous glucose monitors and glucometers, the critical role of fiber and fermented foods, and the supplements Dr. Snyder recommends for optimal brain health. We also address gut health and the misconception that constipation is normal. 
    I am confident you will find my conversation with Dr. Snyder as enlightening and enjoyable as I did.

    IN THIS EPISODE YOU WILL LEARN:

    Why women need to educate themselves about perimenopause and its symptoms

    Common early signs of perimenopause

    How lifestyle choices significantly impact the severity of perimenopause symptoms

    Why women must eat enough protein

    Importance of maintaining stable blood sugar levels

    Benefits of using continuous glucose monitors

    How strength training helps women maintain muscle mass and functional strength

    The benefits of fermented foods for supporting the gut microbiome

    Why managing stress and getting enough sleep are essential

    Brain-boosting supplements Dr. Snyder recommends

    How to avoid constipation 


    Bio: Dr. Mariza Snyder
    Dr. Mariza Snyder is a functional practitioner, women’s hormone expert, and the author of eight books: The newest book, The Essential Oils Menopause Solution, focuses on solutions for women in perimenopause and menopause and the #1 National Bestselling book, The Essential Oils Hormone Solution, focuses on balancing women’s hormones naturally. For the past fifteen years, she has lectured at wellness centers, conferences, and corporations on hormone health, metabolic health, nutrition, and detoxification. She has been featured on Dr. Oz, Oprah Magazine, Fox News Health, MindBodyGreen, and in many publications. Dr. Mariza is also the host of the top-rated Energized Podcast, (with over 11 million downloads) designed to empower women to become the CEO of their health. Check out her website, drmariza.com, for women's hormone tips, including recipes and supplementation. 

    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Mariza Snyder

    On Instagram



    Energized with Dr. Mariza (Podcast)

    Dr. Snyder’s books are available on Amazon 

  • Today, I am thrilled to connect with Farmer Lee Jones, who oversees The Chef's Garden, a family-owned regenerative farm dedicated to cultivating the most flavorful and nutrient-rich vegetables, herbs, and microgreens. 
    With a legacy of over three decades, The Chef's Garden has been the go-to supplier for some of the finest chefs and restaurants worldwide. 
    Join us as we dive deep into the differences between regenerative agriculture and traditional industrial farming, looking at the importance of flavor-focused cultivation, the limitations of USDA guidelines in determining mineral efficacy, how the pandemic affected the operations of the Chef's Garden, the rising trends of seasonal eating in the vegetable industry, and the differences between hybrid and GMO products. 
    Get ready for an enlightening conversation with Farmer Lee Jones, whose infectious enthusiasm for sustainable farming practices is bound to leave you inspired.

    IN THIS EPISODE YOU WILL LEARN:

    The differences between regenerative agriculture and traditional industrial farming

    Why traditional industrial farming is unsustainable, and how it negatively impacts soil and human health

    The benefits of regenerative agriculture

    Why Farmer Lee grows for flavor, not just for nutritional levels

    The importance of maintaining healthy soil 

    How Farmer Lee managed to keep his team together and maintain his farming operations during the pandemic

    Why it is essential to pay attention to the packaging and labeling when purchasing produce

    The nutritional benefits of microgreens

    Farmer Lee explains the difference between GMO and hybrid vegetables

    Why we need to tune into our bodies and understand what they need instead of relying on artificially available produce throughout the year


    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Farmer Lee Jones

    On Instagram   


    The Chef’s Garden on Instagram (For vegetable box subscriptions)

    The Culinary Vegetable Institute on Instagram

  • I am delighted to have Jessie Inchauspe, the Glucose Goddess, joining me on the podcast today!
    Metabolic health is my passion! It is a huge area of focus in my work, and Jessie is truly a gift in the space! She is a rising star author and biochemist with a clear and accessible way of explaining the science behind glucose metabolism. 
    Jessie joins me today to discuss the impact of glucose metabolism and spikes. We dive into her background and how an accident created her pain-to-purpose story. We discuss the role of continuous glucose monitors and how glucose spikes impact our mitochondria, inflammation, and oxidative stress. We get into glycation and aging, how weight gain is a protective aspect of glucose spikes- or hyperglycemia, and the role of vinegar, movement, and fiber. We also talk about Jessie’s new book, her opinions on fasting, and so much more. 
    I loved interviewing Jessie! Her enthusiasm is contagious, and it is easy to understand why she is such a beloved author in the health and wellness space!

    IN THIS EPISODE YOU WILL LEARN:

    Jessie shares how an accident led her to where she is today.

    How a continuous glucose monitor changed everything for Jessie.

    How Jessie came up with her simple principles to steady glucose levels.

    What is the purpose of glucose in the body?

    How do glucose spikes impact our mitochondria?

    Jessie shares a fascinating vinegar hack for reducing side effects and symptoms of glucose spikes.

    How being metabolically unhealthy impacts the aging process.

    The benefits of having savory breakfasts and eating vegetables first with every meal.

    Jessie talks about her new book, The Glucose Goddess Method.

    How gaining weight protects our bodies from the impact of glucose spikes.

    How walking or moving after meals balances blood sugar levels.

    Why is blood sugar so important?


    Connect with Cynthia Thurlow
    Follow on Twitter
    Instagram
    LinkedIn
    Check out Cynthia’s website

    Connect with Jessie Inchauspe
    On her website  
    On Instagram

    Jessie’s books
    The Glucose Goddess Method
    Glucose Revolution

  • I am thrilled to present the last class of our Lipid Masterclass series today with the esteemed Dr. Thomas Dayspring. Dr. Dayspring is board-certified in internal medicine and clinical lipidology and is a fellow of the American College of Physicians and the National Lipid Association. 
    Today, we round things out by diving into medications for lipid abnormalities and discussing lipid physiology, with Dr. Dayspring shedding light on insulin resistance and statins and cautioning against statin use for those predisposed to diabetes or insulin resistance. He also explains why LDL particle size is not worth testing and discusses ways to identify specific laboratory abnormalities. 
    Be sure to stay tuned for the AMA session to follow, where Dr. Dayspring will answer listeners’ questions. 
    It has been a privilege engaging with Dr. Dayspring throughout this masterclass series. I know you will have learned a lot from it!

    IN THIS EPISODE YOU WILL LEARN:
    · The lack of research and consistency in addressing the needs of women in various stages of life
    · Dr. Dayspring discusses the use of bile acid sequestrants for lowering LDL cholesterol
    · Dr. Dayspring discusses the history of bile acid sequestrant use, explaining why their use is limited
    · How bempedoic acid and statins lower LDL cholesterol
    · Potential contraindications for bempedoic acid
    · The benefits and risks of using fibrates to reduce heart attacks
    · Dr. Dayspring explains why fibrates work best for genetic hypertriglyceridemia
    · Why reducing ApoB is essential for atherosclerosis patients, especially for high-risk patients
    · Dr. Dayspring explains why small LDL particles are dangerous
    · The ideal ApoB level for those who have no heart disease and are not diabetic 

    Bio:
    Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular/lipidology educator. Career-wise, he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women’s cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He received the 2011 National Lipid Association’s Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association.

    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Thomas Dayspring

    On Twitter (@DrLipid)

    On LinkedIn

  • I am delighted to reconnect with Dr. Anurag Singh today, the Chief Medical Officer at Timeline Nutrition. He joined me once before on Episode 268. 
    I invited Dr. Singh back to discuss the latest research on GLP-1 agonists like Wegovy, Semaglutide, and Ozempic, which are gaining significant traction with projected sales exceeding $100 billion by 2030, potentially affecting 9% of the US population.
    In our conversation, we explore the contributors to our metabolic health crisis by looking at the research surrounding GLP-1 agonists, the physiology of GLP-1 peptides, and the influencing elements Dr. Singh refers to as the trifecta. We dive into the loss of muscle mass and strength, sarcopenia, and frailty associated with these drugs, and Dr. Singh shares his concerns about their impact on bone health, the gut microbiome, and their use in younger patients. We also get into lifestyle measures, mitochondrial health, hallmarks of aging, Akkermansia, and the importance of advocacy and patient empowerment. 
    Today’s compelling and invaluable discussion with Dr. Anurag Singh highlights crucial insights into GLP-1 agonists and their broader health implications. I know it will provide significant value for our listeners.

    IN THIS EPISODE YOU WILL LEARN:

    Dr. Singh breaks down what GLP-1 agonist drugs are and how they work.

    How our modern-day lifestyles contribute to poor metabolic health

    The benefits and side-effects of using GLP-1 agonist treatments for improving metabolic health

    Why strength training is essential for preventing muscle loss and frailty in middle-aged women

    What are the potential long-term effects of SARMs on muscle mass and health?

    Why dietary counseling is essential for those taking GLP-1 agonist drugs

    The benefits of supplements for boosting mitochondrial health 

    Dr. Singh discusses a research study on combining lithium with GLP-1 agonists to improve the muscle quality of those with muscle-wasting conditions.

    Why akkermansia is essential for GLP production

     
    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website 

    Submit your questions to [email protected]



    Connect with Dr. Anurag Singh

    Timeline

    Mitopure

    Email Dr. Singh: [email protected] 



    Previous Episode Mentioned
    Ep. 268: Understanding the Biology of Aging with Evolved Supplementation and Nutrition, featuring Dr. Anurag Singh

  • Today, I am delighted to reconnect with two previous guests, Dr. Darren Candow.
    Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity who joined me before on Episode 301, where we spoke about creatine. 
    We are doing an AMA session today, delving into various themes surrounding creatine, from debunking outdated RDA recommendations to exploring the synergies between strength training and creatine efficacy. We look into the cognitive benefits of creatine, exploring how it interacts with caffeine and its implications for bone health, hydration, anabolic resistance, and metabolic health. 
    I trust you will find today's AMA session as enlightening and enriching as I did while recording it.

    IN THIS EPISODE YOU WILL LEARN:

    The safety and efficacy of creatine as a supplement

    How creatine increases muscle mass and reduces protein catabolism

    The benefits of combining creatine with protein 

    Is it better to take creatine before or after a workout?

    How creatine supplementation may improve brain performance and mental clarity

    Why exercise is essential for those who want to experience the benefits of creatine for maintaining their bone health

    The benefits of resistance-band workouts for post-menopausal women

    Are there any age-related limits for creatine supplementation?


    Bio: Dr. Darren Candow
    Dr. Darren Candow, PhD, CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training), which have practical and clinical relevance for improving musculoskeletal aging and reducing the risk of falls and fractures. Dr. Candow has published over 120 peer-refereed journal manuscripts, supervised over 20 MSc and PhD students, and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institute of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients, and Frontiers.

    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Darren Candow
    On Instagram and Twitter (now X)

    Previous Episode Mentioned:
    Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Darren Candow, PhD, CSEP-CEP

  • I am honored to have Dr. Carolyn Dean joining me today.
    Dr. Dean is a medical doctor, naturopath, and best-selling author. She has dedicated more than 50 years to integrating the science of medicine with the gifts of nature to help her patients feel better, boost their energy, and take control of their health.
    Today, our conversation centers on The Flexner Report and its influence on modern medicine and the essential role of magnesium in over 80% of metabolic functions. We dive into why we are so magnesium-depleted and common disorders associated with low magnesium levels, and we explore the effects of magnesium on bone health and the microbiome and the synergistic properties of various forms of magnesium and other micronutrients. 
    I am confident you will find today’s discussion with Dr. Carolyn Dean as enjoyable as it is enlightening.

    IN THIS EPISODE YOU WILL LEARN:

    How the Flexner Report has impacted allopathic, functional, and integrative approaches to health and wellness

    Why is magnesium so poorly understood?

    How to get your magnesium accurately tested

    How our modern-day lifestyles are contributing to the current magnesium deficiency epidemic 

    Dr. Dean shares her formula for hydration 

    The potential side effects of allopathic medications and how they impact our health

    Why magnesium is essential for aging women

    The relationship between magnesium and bone health

    The benefits of magnesium supplementation

    The complex relationship between magnesium and other minerals

    Dr. Dean talks about Magnesium Threonate and explains how all magnesium compounds can ultimately reach the brain.


    Bio:
    Carolyn Dean, MD, ND, is a medical doctor, naturopath, and best-selling author. She has spent 50+ years committed to applying the science of medicine and the gifts of nature to help people feel better, find more energy, and take control of their personal health. Dr. Dean follows the 2017 revision of 2004's best-selling book The Magnesium Miracle® with her newest revision Magnesium: The Missing Link to Total Health®.

    Connect with Cynthia Thurlow   

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    Submit your questions to [email protected]



    Connect with Dr. Carolyn Dean

    On her website (For educational resources)

    RnA ReSet Store website


    Podcast 


    Magnesium: The Missing Link to Total Health by Dr. Carolyn Dean is available on Amazon 

    Recommended Publication
    Magnesium in the Central Nervous System

  • I am delighted to reconnect with Dr. Dave Rabin today. He last joined me for Episode 91 in April of 2020.
    Dr. Rabin is a board-certified psychiatrist and neuroscientist. He is the Co-founder and CMO at Apollo Neuroscience, the first scientifically validated wearable system to improve heart rate variability, focus, and relaxation, and helps attain meditative states. He is also Co-founder and Executive Director of the Board of Medicine and a psychedelic clinical researcher, currently evaluating the mechanism of psychedelic-assisted psychotherapy and treatment-resistant illness.
    Today, we examine the value of touch and sensory techniques, discussing the distinctions between sympathetic and parasympathetic vagal tone in the autonomic nervous system, changes in sex hormones during perimenopause and menopause, and how that impacts sympathetic dominance, the development of stress responses, and the concept of stress leading to personal growth. We explore the influence of the vagus nerve on systemic health, explaining what HRV is and how it can demonstrate bodily coherence, and we also dive into wearable technologies like Apollo, the disruption of psychedelic interventions, and the impact of trauma on physical and mental well-being. 
    I am confident that you will find today’s engaging discussion with Dr. Dave Rabin eye-opening and enlightening.
    IN THIS EPISODE YOU WILL LEARN:

    How touch helps us connect, bond, and support our autonomic nervous system

    How finding balance between the parasympathetic and sympathetic nervous systems can help us manage stress and anxiety

    Techniques for quickly restoring balance to the nervous system

    Why women experience more anxiety, depression, and heart arrhythmias during perimenopause

    How breathing techniques can improve heart rate variability 

    The significance of HRV metrics for understanding physical and mental health

    How the Apollo device activates a healing response within the body

    The potential of MDMA and other psychedelics hold for trauma healing


    Connect with Cynthia Thurlow

    Follow on Twitter


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    Submit your questions to [email protected]



    Connect with Dr. Dave Rabin

    On his website


    Apollo

    Instagram

    Twitter (X)

    The Psychedelic Report Podcast

    Your Brain Explained Podcast


    Previous Episode Mentioned
    Ep. 91 – How To Listen To Your Body and DE-STRESS During COVID-19 – with Dr. David Rabin

  • I am thrilled to connect with my friend and colleague, Dr. Tony Youn today. 
    Dr. Youn is a nationally recognized board-certified plastic surgeon and the author of many best-selling books. He has a massive social media presence and hosts the widely acclaimed podcast The Holistic Plastic Surgery Show.
    In our conversation today, we dive into Dr. Youn’s new book, Younger for Life, and he offers valuable insights on skin health and overall well-being. We explore the aging process and address oxidative-free radical damage, chronic inflammation, autophagy, and the impact of processed foods. We also get into helpful supplements for skin support, examine the concept of greenwashing, and discuss sunscreen, exfoliation, in-office treatments, breast implant illness, and the power of lifestyle choices.
    Stay tuned for more!

    IN THIS EPISODE YOU WILL LEARN:

    How to avoid aging too quickly through nutrition and lifestyle changes

    How sugar and seed oils impact skin aging

    The benefits of collagen supplements for healthier skin 

    Hormonal changes that affect the metabolism and skin health after menopause

    The importance of screening the ingredients in skincare products

    How chemical sunscreens differ from physical sunblocks

    Using Retinol for anti-aging and skin health

    Non-invasive fat reduction treatments and their potential risks

    Dr. Youn discusses breast implant illness

    What you need to look out for when using Botox


    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Anthony Youn

    On his website



    Youn Beauty  

    On Instagram, YouTube, TikTok, Facebook, and Twitter


    The Holistic Plastic Surgery Show

    Buy a copy of Younger for Life 

    Bookshop.Org

  • Today, I am thrilled to be connecting with Jillian Turecki, a renowned relationship coach, educator, author, and host of the Jillian on Love podcast. 
    Sought out for her empathetic approach, Jillian has guided 1000s of individuals over the past two decades, driven by an unquenchable curiosity about what makes a relationship thrive. Through her compassion, directness, and authenticity, she has helped them transform their relationships with themselves by focusing on self-growth. 
    In our conversation, we explore the societal expectations for women and how improving our relationships with ourselves allows us to become more authentic in our other relationships. We address loneliness and trauma, unlearning parental conditioning, and dealing with situationships, and get into the difference between sexual chemistry and a real connection, narcissism, and warning signs in relationships. Jillian also shares her perspective on marriage and the importance of self-reflection. 
    Join us for the invaluable insights Jillian has drawn from her extensive experience over the past twenty years. 

    IN THIS EPISODE YOU WILL LEARN:

    How women internalize narratives of weakness due to societal expectations

    How self-esteem impacts relationship choices

    What people can do to empower themselves and avoid feeling alone

    The benefits of self-validation

    What we can do to heal past wounds and foster healthy relationships

    The challenge of distinguishing lust from love

    Why self-awareness is essential within relationships

    Red flags to look out for in relationships

    How to deal with communication breakdowns in relationships

    Tips for moving on from a broken heart


    BIO:
    Jillian Turecki is a certified relationship coach, teacher, author, and host of the Podcast, Jillian On Love. Fueled by an insatiable curiosity about what makes a relationship thrive, Jillian has helped thousands over the last 20 years through her teachings, courses, and writing to revolutionize their relationship with themselves so that they transform their romantic relationships. Jillian is sought out for her compassionate, direct, and very authentic style of coaching, teaching, and writing.

    Connect with Cynthia Thurlow

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Jillian Turecki

    On her website


    On Instagram or Jillian On Love on Instagram


    Jillian On Love Podcast

  • I am honored to connect with Dr. Dave Diamond today.
    Dr. Diamond is a professor at the University of South Florida in their Department of Psychology, Molecular Pharmacology, and Physiology. He has a Ph.D. in biology, specializing in behavioral neuroscience.
    In our discussion today, Dr. Diamond talks about his journey as a neuroscientist and his interest in heart disease, and we discuss how Ancel Keys, the nutritional department at Harvard, and governmental dietary guidelines have significantly hindered our state of health. We explore the diet-heart hypothesis, the effects of seed oils and low-fat diets, the misconceptions surrounding cholesterol, metabolic errors, and the role of insulin resistance in coronary artery disease and metabolic health. We also scrutinize the implications of scientific misconduct, the effects of statins, and the role of nutrition in shaping lipid panels. 
    Join us for today’s valuable, insightful, and informative conversation with Dr. Dave Diamond. 

    IN THIS EPISODE YOU WILL LEARN:

    How Dr. Diamond became a leading voice in heart disease research

    The negative impact of a low-fat, high-carb diet 

    How the American Heart Association ignored the effects of sugar on heart disease

    How seed oils have contributed to the obesity epidemic 

    Why a low-carb diet could increase the risk of heart disease

    How the demonization of cholesterol deflects from nutritional factors exacerbating poor metabolic health

    How the benefits of statins get overstated 

    How statins can lead to strokes and heart attacks and contribute to metabolic damage

    The perils of scientific misconduct and the profit-driven pharmaceutical industry

    The benefits of a low-carb diet


    Connect with Cynthia Thurlow

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    Submit your questions to [email protected]



    Connect with Dr. David Diamond

    On X (Twitter)  

    Email Dr. Diamond: [email protected]

  • I am happy to connect with Coach Bronson Dant today. He has spent over a decade guiding and training people in health and fitness. He discovered the benefits of a whole food animal-based ketogenic diet for optimizing metabolic health and performance and wrote The Ultimate Ketogenic Fitness Book.
    In our discussion today, we dive into the powerful story of Coach Bronson’s pain-to-purpose journey. We explore the value of mindset and look at how age-related changes affect muscle, inflammation, and metabolic flexibility. He shares his three pillars of muscle health related to nutrient density, bioavailability, and satiety, and we examine the importance of sleep, the impact of extremes in exercise, and the value of stress management. We also unravel the complexities of weight loss resistance, and Coach Bronson discusses his research from the Journal of Nutrition Metabolism and Health Science, sharing his perspective on macros and functional movement in menopausal women.

    IN THIS EPISODE YOU WILL LEARN:

    Coach Bronson shares his three pillars for nutrition

    The limitations of basing nutrition on calories alone

    How the hormone piece impacts effective weight management

    How to avoid physical deterioration through fitness and nutrition

    Why Coach Bronson advocates for living life to the fullest and dying quickly

    How does muscle mass impact metabolic health?

    The importance of taking a balanced approach to weight loss

    How sleep aids muscle recovery and growth 

    Stress management, nutrition, and fitness for overall well-being

    How alcohol affects our health and fitness

    The benefits of combining functional movement training and proper nutrition for older adults 


    Connect with Cynthia Thurlow

    Follow on Twitter


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    Submit your questions to [email protected]



    Connect with Bronson Dant

    On his website 

    On YouTube and Instagram



    The Ultimate Ketogenic Fitness Bundle is available on Amazon

  • I am thrilled to connect with Dr. Suzanne Gilberg-Lenz today.
    Dr. Gilberg-Lenz is involved in women's empowerment and public education, appearing frequently to share her expertise in women's health and integrative medicine. She received her medical degree from the USC School of Medicine and did her residency training in obstetrics and gynecology at UCLA Cedars Sinai Medical Center. She is the author of The Menopause Bootcamp. 
    In our discussion, we dive into paradigm shifts and identity differentiation in middle age, debunking the common misconception that our worth ties into our physical attractiveness or the ability to have children. We talk about ageism and the impact of misogyny on sexual education and healthcare, exploring precursors to disease risk in menopause, pelvic floor advocacy, bone and muscle changes in menopause, and the effects of disordered eating on mental health. We also touch on brain remodeling, the three Ps, and how cycle changes can impact our ability to interact with our environment and affect our relationships. 
    I am excited for you to listen to this insightful conversation, which is the first of two discussions with Dr. Gilberg-Lenz.

    IN THIS EPISODE YOU WILL LEARN:

    How women get pressured to conform to societal standards 

    Sexual health education is so important

    Why we need policy changes to address gender-related health disparities

    How our past medical history is essential for predicting our future health outcomes

    The importance of pelvic floor health for women

    The benefits of vaginal estrogen and energy-based devices during menopause 

    Why annual pap smears are essential for sexually active women over 40

    The musculoskeletal changes that occur in menopause

    How disordered eating patterns often get hidden, and how they can worsen with hormonal changes and mood disorders

    How the brain chemistry brain of women gets remodeled with puberty, pregnancy, and menopause


    Bio: Dr. Suzanne Gilberg-Lenz
    A Diplomat of the American College of Obstetrics and Gynecology, Suzanne Gilberg-Lenz, MD, received her medical degree in 1996 from the USC School of Medicine and completed her residency in obstetrics and gynecology at UCLA/Cedars-Sinai Medical Center. Dr. Gilberg-Lenz is involved in women’s empowerment and public education. She appears frequently as an expert in women’s health and integrative medicine in print, online, and on TV, where she is the Chief Medical Correspondent for the Drew Barrymore Show. She is the author of MENOPAUSE BOOTCAMP: Optimize Your Health, Empower Your Self, and Flourish as You Age (Harper Wave; October 11th) 

    Connect with Cynthia Thurlow  

    Follow on Twitter


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    Check out Cynthia’s website


    Submit your questions to [email protected]



    Connect with Dr. Suzanne Gilberg-Lenz

    On her website


    Dr. Gilberg-Lenz on Instagram


    The Menopause Bootcamp on Instagram


    Dr. Gilberg-Lenz’s Menopause Bootcamp