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In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function.
Learn more at drknews.com
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Gradual use of HRT therapy based on age.
08:27 Customized hormone therapy starts with low doses.
13:03 Testosterone therapy aids weight loss in men.
20:15 Testosterone replacement therapy may benefit men with diabetes.
23:10 Testosterone replacement therapy in men is safe.
30:20 Men with low testosterone treated with injections.
35:05 Managing testosterone levels in men, potential issues.
38:09 Dietary and lifestyle strategies impact hormones clinically.
48:13 Music therapy, blood sugar, ketogenic diet, sleep issues.
52:33 Nutraceuticals impact insulin resistance; fasting benefits.
56:09 Women in menopause may experience gallbladder issues.
01:03:26 Nutraceutical protocols, insulin signaling, PCOS treatment options.
01:10:20 Evaluate hypoglycemia, insulin resistance, and dietary history.
01:16:18 Decide on hormone therapy based on risks.
01:17:43 Understanding aging and its impact on health.
01:22:32 Podcast content not a substitute for medical advice.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options available.
Learn more at drknews.com
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com
00:00 Female and male hormone transition patterns summarized.
08:51 BMI impacts endocrine system, genetic factors matter.
12:40 Excessive estrogen production causes gynecomastia in men.
18:51 Prostaglandins influence menstrual pain and discomfort.
26:21 Causes of heavy or light menstrual bleeding.
32:24 High DHE and testosterone levels suggest PCOS.
33:24 PCOS symptoms can normalize with metabolic control.
38:45 PCOS pathophysiology, treatment, and clinical manifestations.
45:19 Adrenal glands help manage perimenopausal symptoms.
49:33 Hormonal changes in perimenopause cause inflammatory response.
59:03 Inflammation and hormones affect women's health.
01:03:18 Menopause can worsen underlying health conditions.
01:06:44 Adulthood: decline in male function and symptoms.
01:13:49 LH levels range indicates potential hormone balance.
01:16:27 Free testosterone is crucial, especially as we age.
01:25:04 Normal range testosterone, relative hypogonad men, DHT.
01:27:26 Male and female hormone disorders patterns explained.
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Saknas det avsnitt?
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In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance and regulating testosterone.
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
00:00 Transitioning off HRT may benefit from modulators.
06:05 Flavonoids affect estrogen receptor, 4 key foods.
10:05 Healthy microbiome diversity enhances effectiveness of soy products.
11:16 Carbs impact conversion of phytoestrogens efficiently.
16:29 Gut health crucial for managing estrogen disorders.
18:57 Diet, lifestyle, supplements affect microbiome diversity.
20:53 Liver pathways detoxifying hormones, potential competition. Nutrients aid hepatic inflammation support.
26:51 Essential fatty acids are critical for health.
30:29 Prostate glands cause pelvic issues, need support.
34:19 Men's testosterone, estrogen testing, insulin resistance, obesity, blood sugar imbalances, hypoglycemia, insulin resistance, dietary guidelines.
36:02 Optimize diet to prevent blood sugar crashes.
39:41 Review found herbal medicines improve PCOS symptoms.
42:41 Aggressive protocol for PCOS using nutraceuticals.
47:19 Nutraceuticals may protect serotonin cells, boost testosterone.
50:44 Botanicals boost testosterone levels but may vary.
53:42 Glial cells switch to pro-inflammatory state. Hormone changes amplify neuroinflammation.
56:35 Peptides stimulate hormones, potential for endocrine treatment.
58:37 Dr. Kharrazian's podcast and blog information.
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In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian discusses blood glucose management, gut health, and the impact of hormone deficiencies on mitochondrial function and other aspects of physiology.
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
Learn more at drknews.com
Timestamps:
00:00 Hormones impact mitochondria, affecting cellular function.
09:31 Mitochondrial health affects recovery and signaling pathways.
12:00 Hormone replacement may fix mitochondrial dysfunction. Stress affects mitochondria.
16:22 Certain genetic factors can increase health risks.
25:26 Aromatization causes body fat increase, vicious cycle.
31:00 Estrogen drop in women leads to fat tissue.
32:52 Steroid use can disrupt endocrine system balance.
42:35 Healthy adrenal function is crucial in perimenopause.
48:03 Adrenal gland imbalances and stress responses summarized.
53:04 Insulin resistance causes blood sugar roller coaster.
57:10 Symptom patterns indicating early stages of insulin resistance.
01:02:30 Gut bacteria convert chemicals and hormones.
01:08:19 Hormone deficiency causes leaky gut, affecting health.
01:12:26 Inflammatory diets cause low testosterone levels.
01:20:18 Hormones critical for health and disease prevention.
01:23:28 Hormone imbalances affect brain recovery and health.
01:28:20 For more info visit drknews.com/podcast.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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In today's episode, we dive into the impact of hormone imbalance on overall health. From the critical role of adequate sleep in hormone regulation to the potential effects of environmental chemicals on endocrine function, Dr. Kharrazian shares valuable insights and evidence-based strategies for managing hormone imbalances.
For patient-oriented courses, visit https://drknews.com/online-courses/
For CE and CME practitioner courses, visit https://kharrazianinstitute.com/
Learn more at drknews.com
00:00 Toxic chemicals in everyday products, impacts on health.
09:13 Endocrine disrupting chemicals impact female reproductive function.
12:57 Endocrine disrupting chemicals impact PCOS in females.
18:47 Endocrine disrupting chemicals impact serious health conditions.
22:17 Inflammation impacts male testosterone and female infertility.
32:18 Aquifers impact water supply with hormones, pharmaceuticals.
34:54 Use multiple layers of water filtering systems.
43:10 Air pollution impacts cortisol and microbiome health.
48:26 Intense exercise is important for hormonal balance.
52:57 Low or high body mass affects hormones.
58:06 Injections are crucial for male obesity issues.
01:03:36 Muscle mass affects health risks in obesity.
01:08:32 Suppressed FSH, low TSH, hormone-related issues.
01:12:27 Hormones, sleep, and strategies for better rest.
01:19:50 Minimum needed protein is 1g/lb body weight.
01:24:18 Blood sugar: Hypoglycemia vs insulin resistance management.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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In this episode, we take a deep dive into the intricate world of hormone imbalances and hormone replacement therapy. Dr. Kharrazian discusses the latest research findings, revealing a clear linear dose-response relationship between oral contraceptive use and the risk of hypertension, as well as the links between hormone replacement therapy and various health concerns. We explore the complexities of hormone disorders and the need for a personalized approach to treatment, discussing the impact of hormones on clinical function, the liver, and the gut microbiome. Join us as we uncover the vital connection between hormones and overall health, as well as the challenges individuals face in receiving appropriate evaluation and treatment for hormone-related issues in the current healthcare system.
Learn more at drknews.com
00:00 Hormone disorders treated with diverse approaches.
08:13 Hormone replacement therapies and over-the-counter options.
14:10 Different types of hormonal contraceptives can cause weight gain and mood disorders.
18:50 Glial cells produce main hormone for synaptic activity.
25:45 Hormone replacement therapy not recommended for everyone.
30:43 Testosterone therapy shows health benefits with low risk.
37:49 Variety of lifestyle strategies for hormone balance.
39:54 Viral infection may require immediate symptom management.
48:43 Stimulating dysfunctional gland, hormones, pituitary issues, hormones.
53:18 Protein pathways impact hormone levels causing symptoms.
58:19 Androgel may not effectively metabolize into hormones.
01:02:16 Microbiome dysbiosis consequences, particularly linked to hormones.
01:08:23 Estradiol strongest, estrone not as strong.
01:11:19 Urinary labs may not accurately test hormones.
01:16:20 Maintain resiliency for hormone levels, health longevity.
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In this talk, Dr. Kharrazian reviews the many pathways through which inflammation impacts the body. In a nutshell, inflammation is like throwing fuel onto the fire. Wherever you already have issues with pain or inflammation, an inflammatory diet and other triggers will simply worsen those conditions. Aging is another consideration — as we age we naturally become more prone to inflammation due to the gradual decline of the body's antioxidant systems. You will learn about these mechanisms, how to find triggers of inflammation, and anti-inflammatory and antioxidant strategies to mitigate the damage.
Find out more on drknews.com.
[00:00:24] . So now, when you're looking at what causes inflammation, the first answer is an imbalance of free radicals and antioxidants. Inflammation can also be caused by an imbalance of our microbiome. Systemic inflammation caused by imbalance of free radicals/antioxidants and microbiome.
[00:23:37] Antioxidants and anti-inflammatories protect body from free radicals; various compounds have different mechanisms; common ones include vitamin E, fish oils, antihistamines, resveratrol, turmeric, vitamin A, vitamin C, and liposomal glutathione.
[00:26:06] C reactive protein is a blood biomarker used as a general marker for inflammation. High levels (over 3 or 5) can indicate disease, but not all inflammation increases production of CRP.
[00:30:21] Insulin resistance causes chronic inflammation, immune response, free radicals and oxidative stress, leading to tissue damage.
[00:32:30] Exercise can cause inflammation in those with chronic conditions, so they should work their way up, clean their diet, and take antioxidants.
[00:34:45] Neurogenic inflammation triggered by stress, lack of sleep and unhealthy relationships.
[00:37:52] Turmeric has active curcuminoids that have an anti-inflammatory effect; people have different cost-benefit ratios for using it; other anti-inflammatory compounds may be more effective for some people.
[00:43:36] Gut Puzzle program teaches diet, lifestyle, and understanding of gut dysfunctions to treat sibo and other conditions.
[00:46:41] Cortisol has a bi-directional effect on inflammation, health, and gut; acute stress is anti-inflammatory, chronic stress is catabolic and can create inflammatory responses.
[00:51:09] Gut motility problems, such as those caused by inflammation and neurodegenerative diseases, can lead to chronic constipation. Gut Health Puzzle program teaches how to address these issues.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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The concept of small intestinal bacterial overgrowth is one that is becoming very popular but also widely misunderstood and confusing. Compared to the large intestine, there are very few bacterial species in the small intestine. When SIBO happens, the bacteria in the large intestine translocate to the small intestine causing fermentation, bloating, and excessive distension. Foods that commonly trigger SIBO symptoms include fibrous foods, sugar, sweeteners, prebiotics, and fermented foods.
However, not all bloating and distension is SIBO. This is where confusion comes from. In this episode, I discuss how to tell it really is SIBO, SIBO tests, what causes it, and what to do about it.
Find out more on drknews.com.
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Chronic gut health problems some people face can stem from brain-related dysfunction. Key groups of brain-related problems can cause gut problems: neurodegeneration, traumatic brain injury, neurological autoimmunity, and neurodevelopment disorders.
In this episode, I discuss these key categories of brain-related problems and how they affect the gut through the vagus nerve as one of its functions is activating the gastrointestinal tract.
Find out more on our website at Drknews.com.
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Glutathione is the body’s master antioxidant, meaning it helps protect your cells from pathogens such as viruses. It also lowers the risk of developing food and chemical sensitivities, and is a powerful ally in managing autoimmunity and preventing tissue destruction.
Unfortunately, environmental toxins, chronic stress, unhealthy diets, inflammation, medications, alcohol, aging, and many other factors continually deplete glutathione. Making sure your glutathione status is strong and reducing glutathione depletion can play a profound role in immune resilience to viruses and in managing autoimmune disease, inflammation, chemical sensitivities, food sensitivities, and other chronic health issues.
In this podcast, Dr Kharrazian discusses what glutathione really is, and the supplements and precursors that come in many different forms. How do you know which one to take? How much should you take? How can you tell it's working?
Find out more on our website at Drknews.com
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A complete thyroid panel can tell you about thyroid function, feedback loops, and how thyroid hormones are converting. The main thyroid markers are TSH, the pituitary hormone-stimulating gland, and T4 and T3, which are produced by the thyroid gland. Thyroid hormones are bound to proteins called thyroid hormone-binding globulins. Those are total T4 and total T3. T4 is converted to T3, which also makes reverse T3. At some point, thyroid-binding globulin levels release the T3 and T4, which then become free T3 and free T4. You can have defects all along these pathways, which I discuss in this podcast.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
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If you have hypothyroidism, the first question you have to ask yourself is how long did it take to finally get diagnosed? Most people do not receive a diagnosis immediately after symptoms appear. What happens to most people instead is they struggle with symptoms for months or years: Hair loss, constipation, cold hands and feet, fatigue – symptoms get worse and worse and they keep developing new ones. Yet their doctor says their lab tests are normal until their thyroid function is bad enough to receive a diagnosis or they find a knowledgeable doctor. By then their body has been deprived of thyroid hormone for quite some time. One problem that can lead to is gallbladder sludge and gallstones. Gallbladder congestion in turns leads to poor absorption of fat-soluble vitamins such as vitamin D, which cascades into other health problems.
This is one reason gallbladder issues are so common among hypothyroid patients.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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If you have hypothyroidism, there is a greater than 90% chance that Hashimoto's, an autoimmune disease, is the cause of your hypothyroidism. If you have one autoimmune disease, then you probably have other autoimmune diseases.
Researchers once believed that autoimmunity was an isolated dysfunction of the gland from an autoimmune response that had no other systemic effects.
Current research shows autoimmunity stems from immune dysregulation and loss of immune tolerance – meaning the immune system loses tolerance to foods, chemicals, and its own body tissue.
This means that any tissue in the body is vulnerable to autoimmunity, and that the mechanisms that set into motion one autoimmune disease can lead to another.
The goal is to regulate immune function and drive autoimmune expression into remission, which will lower your risk of developing future autoimmune diseases.
You do this by identifying your triggers and following strategies that dampen inflammation and boost immune *regulation.* How you do this makes up the bulk of my content on my site (drknews.com) and in my books (on amazon).
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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The two main antibodies to screen for Hashimoto’s are thyroid peroxidase (TPO) antibodies and thyroglobulin (Tg) antibodies. It’s important to check both because either one can be elevated, although TPO is more commonly elevated. An important thing to understand about thyroid antibodies, which are used to screen for autoimmune Hashimoto’s hypothyroidism, is that the antibody itself isn't directly related to the severity of the disease. The T cell immune response, which attacks tissue tagged by antibodies, also plays a role.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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Why is it so difficult to get diagnosed with hypothyroidism and Hashimoto's in the current healthcare system? As a healthcare practitioner, it's pretty rare when a patient says, "Yeah, I had symptoms and right away they diagnosed me with hypothyroidism.” Several reasons go into why it’s hard to get a hypothyroidism diagnosis:
• The disease comes on slowly so it can go misdiagnosed for years.
• Doctors do not screen for thyroid antibodies that would catch early Hashimoto’s because it’s not covered by insurance or considered standard of care.
• Conventional lab ranges are too wide.
• TSH can fluctuate up and down and may be normal at the time of the test.
• HMO doctors are assessed based on how much each of their patients cost and avoid tests they feel are unnecessary.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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In this episode Dr. Kharrazian discusses the commonly asked question, which thyroid hormone replacement works best? The important thing to understand is there is not one optimal thyroid replacement. Issues exist with all types of replacement depending on the person and their unique situation and needs. Each person must figure out what their challenges and needs are and which thyroid hormone is most appropriate for them.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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Do you feel sleepy after you eat? Or do you feel energized after eating? Both responses indicate blood sugar instability. Chronically high blood sugar, low blood sugar, or swings between the two cause Hashimoto's flare ups and make the condition difficult to manage. At the same time, if you're in a low thyroid state from undiagnosed or poorly managed Hashimoto's, you're also susceptible to poor blood sugar handling. Low thyroid states both prevent uptake of glucose and promote insulin resistance.
Subscribe to be notified of the free Hashimoto's webinar at drknews.com.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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Today’s world is very toxic, and we all carry toxic chemicals and heavy metals in our bodies. Chelation is a popular therapy to lower heavy metal levels, however it’s important to be aware of the risks—chelation can significantly worsen health in vulnerable people. Factors to consider include your antioxidant status, blood-brain barrier permeability, immune tolerance, gut health, autoimmune status, microbiome, and more. In this talk, Dr. Kharrazian covers heavy metal and chemical toxicity, risk factors to consider before chelation, forms of heavy metal testing, and daily strategies to lower the burden of toxins on your body.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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Endotoxemia happens when toxic byproducts from harmful gut bacteria escape through a leaky gut wall into the bloodstream. Here, they trigger significant inflammation throughout the body. Endotoxemia is linked with major depressive disorder, autoimmunity, joint disease, skin problems, poor immune resilience, difficulty recovering, aging poorly, and more. In fact, one thing people who live to 100 have in common is low levels of endotoxemia. Research also shows people with endotoxemia have a lower chance of surviving a critical illness or sepsis. In this talk, Dr. Kharrazian talks about the factors that cause endotoxemia, why it is considered the most severe form of leaky gut, and strategies for recovery. A Q&A with viewers follow. (From his Facebook Live 12-17-2020). To learn more about improving gut health, visit the online course Gut Health: Solving the Puzzle.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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Contrary to popular belief, gluten intolerance is not a fad. Rates of gluten intolerance have risen dramatically due to many factors of industrialization. Unsurprisingly, significant links exist between gluten and autoimmunity, particularly Hashimoto's hypothyroidism. People with Hashimoto's low thyroid are more genetically prone to gluten sensitivity and celiac disease. Standard gluten sensitivity testing misses about 20% of positive cases because they only test for alpha gliadin. In truth, people can react to multiple compounds in wheat, which should be included in immune reactivity testing. Testing should also screen for the transglutaminase antibodies typically seen in celiac disease, a more destructive form of gluten sensitivity. Learn more in this podcast about how to correctly identify a gluten sensitivity and follow a gluten-free diet to better manage your Hashimoto's or other autoimmune disease.
To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.
Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.
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- Visa fler
